Search by PDB author - Protein Data Bank Japan

English 日本語简体中文繁體中文 한국어

✖

Menu

RCSB PDB PDBe BMRB Adv. Search Search help

Search by PDB author

Visualize

BU of 7ovd by Molmil

Human soluble adenylyl cyclase in complex with the inhibitor TDI10229
Descriptor:	1,2-ETHANEDIOL, 4-chloranyl-6-[1,5-dimethyl-4-(phenylmethyl)pyrazol-3-yl]pyrimidin-2-amine, ACETATE ION, ...
Authors:	Steegborn, C, Quast, J.
Deposit date:	2021-06-14
Release date:	2021-10-06
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10). Acs Med.Chem.Lett., 12, 2021

Visualize

BU of 4d5c by Molmil

tetracycline repressor class J, apo form
Descriptor:	SULFATE ION, TETRACYCLINE REPRESSOR PROTEIN TETR
Authors:	Palm, G.J, Quast, J, Hinrichs, W.
Deposit date:	2014-11-03
Release date:	2016-01-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Domain Movement in Tetracycline Repressor Classes To be Published

Visualize

BU of 4d5f by Molmil

tetracycline repressor class H, apo form
Descriptor:	CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:	Palm, G.J, Quast, J, Hinrichs, W.
Deposit date:	2014-11-04
Release date:	2016-01-20
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Domain Movement in Tetracycline Repressor Classes To be Published

Visualize

BU of 8co7 by Molmil

Crystal structure of human soluble adenylyl cyclase (sAC) in complex with inhibitor TDI-09066
Descriptor:	1,2-ETHANEDIOL, 4-chloranyl-6-[1-methyl-4-(thiophen-2-ylmethyl)pyrazol-3-yl]pyrimidin-2-amine, ACETATE ION, ...
Authors:	Steegborn, C.
Deposit date:	2023-02-27
Release date:	2024-01-03
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. J.Chem.Inf.Model., 63, 2023

Visualize

BU of 8cot by Molmil

Complex of human soluble adenylyl cyclase 10 catalytic core with inhibitor TDI-10962
Descriptor:	1,2-ETHANEDIOL, 2-(dimethylamino)ethyl 5-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-2-methyl-4-(phenylmethyl)pyrazole-3-carboxylate, ACETATE ION, ...
Authors:	Steegborn, C, Fushimi, M.
Deposit date:	2023-02-28
Release date:	2023-04-26
Last modified:	2023-05-17
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. J.Chem.Inf.Model., 63, 2023

Visualize

BU of 8cnh by Molmil

Crystal structure of human soluble adenylyl cyclase (sAC) in complex with inhibitor TDI-10512
Descriptor:	1,2-ETHANEDIOL, ACETATE ION, Adenylate cyclase type 10, ...
Authors:	Steegborn, C.
Deposit date:	2023-02-23
Release date:	2023-04-26
Last modified:	2023-05-17
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. J.Chem.Inf.Model., 63, 2023

Visualize

BU of 8coj by Molmil

Crystal structure of human soluble adenylyl cyclase catalytic domain in complex with the inhibitor TDI-10228
Descriptor:	1,2-ETHANEDIOL, 4-chloranyl-6-[4-[(3-fluorophenyl)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-amine, ACETATE ION, ...
Authors:	Steegborn, C, Fushimi, M.
Deposit date:	2023-02-28
Release date:	2023-04-26
Last modified:	2023-05-17
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. J.Chem.Inf.Model., 63, 2023

218853

PDB entries from 2024-04-24

PDB statistics

PDBj update info

Contact PDBj

numon