3UCC | | ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-1-PGA/PEP | | Descriptor: | Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ... | | Authors: | Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L. | | Deposit date: | 2011-10-26 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UCD | | ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-2-PGA/PEP | | Descriptor: | Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ... | | Authors: | Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L. | | Deposit date: | 2011-10-26 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJE | | ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-3-PGA/PEP | | Descriptor: | Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ... | | Authors: | Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L. | | Deposit date: | 2011-11-07 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJF | | ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-4-PGA/PEP | | Descriptor: | Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ... | | Authors: | Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L. | | Deposit date: | 2011-11-07 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJR | | ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-5-PGA/PEP | | Descriptor: | Gamma-enolase, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID, ... | | Authors: | Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L. | | Deposit date: | 2011-11-08 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJS | | ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-6-PGA/PEP | | Descriptor: | Gamma-enolase, MAGNESIUM ION, (2R)-3-oxo-2-(phosphonooxy)propanoic acid, ... | | Authors: | Qin, J., Chai, G., Brewer, J., Lovelace, L., Lebioda, L. | | Deposit date: | 2011-11-08 | | Release date: | 2012-08-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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4E26 | | BRAF IN COMPLEX WITH AN ORGANIC INHIBITOR 7898734 | | Descriptor: | Serine/threonine-protein kinase B-raf, 5-chloro-7-[(R)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol | | Authors: | Qin, J., Xie, P., Ventocilla, C., Zhou, G., Vultur, A., Chen, Q., Herlyn, M., Winkler, J., Marmorstein, R. | | Deposit date: | 2012-03-07 | | Release date: | 2012-05-09 | | Last modified: | 2013-01-09 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Identification of a Novel Family of BRAF(V600E) Inhibitors.
J.Med.Chem., 55, 2012
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6MIF | | LIM5 DOMAIN OF PINCH1 PROTEIN | | Descriptor: | LIM and senescent cell antigen-like-containing domain protein 1, ZINC ION | | Authors: | Qin, J., Vaynberg, J. | | Deposit date: | 2018-09-19 | | Release date: | 2018-10-31 | | Method: | SOLUTION NMR | | Cite: | Lim5 domain of PINCH1 protein
To Be Published
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2AKM | | FLUORIDE INHIBITION OF ENOLASE: CRYSTAL STRUCTURE OF THE INHIBITORY COMPLEX | | Descriptor: | Gamma enolase, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Qin, J., Chai, G., Brewer, J.M., Lovelace, L.L. | | Deposit date: | 2005-08-03 | | Release date: | 2006-03-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
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2AKZ | | FLUORIDE INHIBITION OF ENOLASE: CRYSTAL STRUCTURE OF THE INHIBITORY COMPLEX | | Descriptor: | Gamma enolase, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Qin, J., Chai, G., Brewer, J.M., Lovelace, L.L. | | Deposit date: | 2005-08-04 | | Release date: | 2006-03-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
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2EVK | | THE STRUCTURES OF THIOLATE- AND CARBOXYLATE-LIGATED FERRIC H93G MYOGLOBIN: MODELS FOR CYTOCHROME P450 AND FOR OXYANION-BOUND HEME PROTEINS | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ACETIC ACID | | Authors: | Qin, J., Perera, R., Lovelace, L.L., Dawson, J.H., Lebioda, L. | | Deposit date: | 2005-10-31 | | Release date: | 2006-04-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of thiolate- and carboxylate-ligated ferric H93G myoglobin: models for cytochrome P450 and for oxyanion-bound heme proteins.
Biochemistry, 45, 2006
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2EVP | | THE STRUCTURES OF THIOLATE- AND CARBOXYLATE-LIGATED FERRIC H93G MYOGLOBIN: MODELS FOR CYTOCHROME P450 AND FOR OXYANION-BOUND HEME PROTEINS | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, BETA-MERCAPTOETHANOL | | Authors: | Qin, J., Perera, R., Lovelace, L.L., Dawson, J.H., Lebioda, L. | | Deposit date: | 2005-10-31 | | Release date: | 2006-03-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins(,).
Biochemistry, 45, 2006
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2KBX | | SOLUTION STRUCTURE OF ILK-PINCH COMPLEX | | Descriptor: | Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ZINC ION | | Authors: | Qin, J. | | Deposit date: | 2008-12-10 | | Release date: | 2008-12-30 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Cytosketal proteins
To be Published
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1CQG | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, 31 STRUCTURES | | Descriptor: | THIOREDOXIN, REF-1 PEPTIDE | | Authors: | Clore, G.M., Qin, J., Gronenborn, A.M. | | Deposit date: | 1996-04-02 | | Release date: | 1996-08-01 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
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1CQH | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | THIOREDOXIN, REF-1 PEPTIDE | | Authors: | Clore, G.M., Qin, J., Gronenborn, A.M. | | Deposit date: | 1996-04-02 | | Release date: | 1996-08-01 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
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4RLO | | HUMAN P70S6K1 WITH RUTHENIUM-BASED INHIBITOR EM5 | | Descriptor: | Ribosomal protein S6 kinase beta-1, [(amino-kappaN)methanethiolato](3-fluoro-9-hydroxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium, GLYCEROL, ... | | Authors: | Domsic, J.F., Barber-Rotenberg, J., Salami, J., Qin, J., Marmorstein, R. | | Deposit date: | 2014-10-17 | | Release date: | 2015-01-21 | | Method: | X-RAY DIFFRACTION (2.527 Å) | | Cite: | Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
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4RLP | | HUMAN P70S6K1 WITH RUTHENIUM-BASED INHIBITOR FL772 | | Descriptor: | p70S6K1, [(amino-kappaN)methanethiolato](3-fluoro-9-methoxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(N-methyl-1,4,7-trithiecan-9-amine-kappa~3~S~1~,S~4~,S~7~)ruthenium, CHLORIDE ION | | Authors: | Domsic, J.F., Barber-Rotenberg, J., Salami, J., Qin, J., Marmorstein, R. | | Deposit date: | 2014-10-17 | | Release date: | 2015-01-21 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
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1MDI | |
1MDJ | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB) | | Descriptor: | THIOREDOXIN, TARGET SITE IN HUMAN NFKB | | Authors: | Clore, G.M., Qin, J., Gronenborn, A.M. | | Deposit date: | 1995-02-27 | | Release date: | 1995-06-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
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1MDK | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB) | | Descriptor: | THIOREDOXIN, TARGET SITE IN HUMAN NFKB | | Authors: | Clore, G.M., Qin, J., Gronenborn, A.M. | | Deposit date: | 1995-02-27 | | Release date: | 1995-06-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
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1TRS | |
1TRU | |
1TRV | |
1TRW | |
5EJC | | CRYSTAL STRUCTURAL OF THE TSC1-TBC1D7 COMPLEX | | Descriptor: | TBC1 domain family member 7, Hamartin | | Authors: | Wang, Z., Qin, J., Gong, W., Xu, W. | | Deposit date: | 2015-11-01 | | Release date: | 2016-03-02 | | Last modified: | 2016-05-11 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
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