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1I17
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BU of 1i17 by Molmil
NMR STRUCTURE OF MOUSE DOPPEL 51-157
Descriptor: PRION-LIKE PROTEIN
Authors:Mo, H, Moore, R.C, Cohen, F.E, Westaway, D, Prusiner, S.B, Wright, P.E, Dyson, H.J.
Deposit date:2001-01-31
Release date:2001-03-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Two different neurodegenerative diseases caused by proteins with similar structures.
Proc.Natl.Acad.Sci.USA, 98, 2001
1CU4
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BU of 1cu4 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, RECOGNITION PEPTIDE
Authors:Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
Deposit date:1999-08-20
Release date:2000-04-17
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
1CR9
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BU of 1cr9 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4
Descriptor: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN
Authors:Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
Deposit date:1999-08-14
Release date:2000-04-17
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
2HH0
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BU of 2hh0 by Molmil
Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope.
Descriptor: Heavy Chain, P-Clone Fab, Chimera, ...
Authors:Kanyo, Z.K.
Deposit date:2006-06-27
Release date:2006-12-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation
J.Mol.Biol., 363, 2006
9BXI
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BU of 9bxi by Molmil
Paired Helical Filament of tau amyloids found in Down Syndrome individuals
Descriptor: Microtubule-associated protein tau
Authors:Tse, E, Ghosh, U, Condello, C, Southworth, D.
Deposit date:2024-05-22
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold.
Acta Neuropathol Commun, 12, 2024
1B10
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BU of 1b10 by Molmil
SOLUTION NMR STRUCTURE OF RECOMBINANT SYRIAN HAMSTER PRION PROTEIN RPRP(90-231) , 25 STRUCTURES
Descriptor: PROTEIN (PRION PROTEIN)
Authors:James, T.L, Liu, H, Ulyanov, N.B, Farr-Jones, S.
Deposit date:1998-11-25
Release date:1998-12-02
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform.
Proc.Natl.Acad.Sci.USA, 94, 1997
9BXO
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BU of 9bxo by Molmil
Straight Filament of tau amyloids found in Down Syndrome individuals
Descriptor: Microtubule-associated protein tau
Authors:Tse, E, Ghosh, U, Condello, C, Southworth, D.
Deposit date:2024-05-22
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold.
Acta Neuropathol Commun, 12, 2024
9BXR
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BU of 9bxr by Molmil
Straight Filaments purified from Down Syndrome individual brain tissue applied to graphene oxide antibody affinity grids
Descriptor: Microtubule-associated protein tau
Authors:Tse, E, Ghosh, U, Condello, C, Southworth, D.
Deposit date:2024-05-22
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold.
Acta Neuropathol Commun, 12, 2024
9BXQ
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BU of 9bxq by Molmil
Paired Helical Filaments purified from Down Syndrome individual brain tissue applied to graphene oxide antibody affinity grids
Descriptor: Microtubule-associated protein tau
Authors:Tse, E, Ghosh, U, Condello, C, Southworth, D.
Deposit date:2024-05-22
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold.
Acta Neuropathol Commun, 12, 2024
8FUG
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BU of 8fug by Molmil
Alzheimer's disease paired-helical filament in complex with PET tracer GTP-1
Descriptor: (5S)-2-[4-(2-fluoroethyl)piperidin-1-yl]pyrimido[1,2-a]benzimidazole, Microtubule-associated protein tau
Authors:Merz, G.E, Tse, E, Southworth, D.R.
Deposit date:2023-01-17
Release date:2023-06-07
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments.
Nat Commun, 14, 2023

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