Author results

6DRU
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XYLOSIDASE FROM ASPERGILLUS NIGER
Descriptor:Glycosyl hydrolases family 31 family protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Cao, H., Xu, W., Betancourt, M., Walton, J.D., Brumm, P., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2018-06-13
Release date:2018-08-22
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an alpha-xylosidase from Aspergillus niger in complex with xyloglucan fragment
To Be Published
6DA6
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CRYSTAL STRUCTURE OF THE TTND DECARBOXYLASE FROM THE TAUTOMYCETIN BIOSYNTHESIS PATHWAY OF STREPTOMYCES GRISEOCHROMOGENES, APO FORM AT 2.6 A RESOLUTION (P212121)
Descriptor:UbiD-like decarboxylase, MAGNESIUM ION, GLYCEROL, ...
Authors:Han, L., Rudolf, J.D., Chang, C.-Y., Miller, M.D., Soman, J., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2018-05-01
Release date:2018-10-03
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.
ACS Chem. Biol., 13, 2018
6DA7
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CRYSTAL STRUCTURE OF THE TTND DECARBOXYLASE FROM THE TAUTOMYCETIN BIOSYNTHESIS PATHWAY OF STREPTOMYCES GRISEOCHROMOGENES WITH APO FORM AT 1.83 A RESOLUTION (I222)
Descriptor:UbiD-like decarboxylase, SODIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Han, L., Rudolf, J.D., Chang, C.-Y., Miller, M.D., Soman, J., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2018-05-01
Release date:2018-10-03
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.
ACS Chem. Biol., 13, 2018
6DA9
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CRYSTAL STRUCTURE OF THE TTND DECARBOXYLASE FROM THE TAUTOMYCETIN BIOSYNTHESIS PATHWAY OF STREPTOMYCES GRISEOCHROMOGENES WITH FMN BOUND AT 2.05 A RESOLUTION
Descriptor:UbiD-like decarboxylase, FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, ...
Authors:Han, L., Rudolf, J.D., Chang, C.-Y., Miller, M.D., Soman, J., Xu, W., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2018-05-01
Release date:2018-10-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.
ACS Chem. Biol., 13, 2018
6D2V
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APO STRUCTURE OF TERB, AN NADP DEPENDENT OXIDOREDUCTASE IN THE TERFESTATIN BIOSYNTHESIS PATHWAY
Descriptor:TerB Oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOCYANATE ION, ...
Authors:Clinger, J.A., Elshahawi, S.I., Zhang, Y., Hall, R.P., Liu, Y., Thorson, J.S., Phillips Jr., G.N.
Deposit date:2018-04-14
Release date:2018-06-13
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published
6D34
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APO CRYSTAL STRUCTURE OF TERC, A TERFESTATIN BIOSYNTHESIS ENZYME
Descriptor:TerC, ISOPROPYL ALCOHOL
Authors:Clinger, J.A., Elshahawi, S.I., Zhang, Y., Hall, R.P., Liu, Y., Thorson, J.S., Phillips Jr., G.N.
Deposit date:2018-04-14
Release date:2018-06-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published
6CKY
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CRYSTAL STRUCTURE OF UCMS2
Descriptor:Glyoxalase
Authors:Chang, C.Y., Chang, C., Annaval, T., Babnigg, G., Phillips Jr., G.N., Joachimiak, A., Shen, B.
Deposit date:2018-03-01
Release date:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of UcmS2
To Be Published
6BMG
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STRUCTURE OF RECOMBINANT DWARF SPERM WHALE MYOGLOBIN (OXY)
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, OXYGEN MOLECULE, ...
Authors:Samuel, P.P., Miller, M.D., Xu, W., Alvarado, S., Phillips Jr., G.N., Olson, J.S.
Deposit date:2017-11-14
Release date:2017-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure of Recombinant Dwarf Sperm Whale Myoglobin (Oxy)
To Be Published
6BBX
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TNM C
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2R,3R)-2,3-dihydroxy-3-[(1aS,11S,11aR,14Z,18R)-3,7,8,18-tetrahydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]butanoate
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-10-19
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
6AX6
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THE CRYSTAL STRUCTURE OF A LYSYL HYDROXYLASE FROM ACANTHAMOEBA POLYPHAGA MIMIVIRUS
Descriptor:Procollagen lysyl hydroxylase and glycosyltransferase, IODIDE ION, FE (II) ION
Authors:Guo, H., Tsai, C., Miller, M.D., Alvarado, S., Tainer, J.A., Phillips Jr., G.N., Kurie, J.M.
Deposit date:2017-09-06
Release date:2018-02-21
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
Nat Commun, 9, 2018
6AX7
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THE CRYSTAL STRUCTURE OF A LYSYL HYDROXYLASE FROM ACANTHAMOEBA POLYPHAGA MIMIVIRUS
Descriptor:Procollagen lysyl hydroxylase and glycosyltransferase, FE (II) ION
Authors:Guo, H., Tsai, C., Miller, M.D., Alvarado, S., Tainer, J.A., Phillips Jr., G.N., Kurie, J.M.
Deposit date:2017-09-06
Release date:2018-02-21
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
Nat Commun, 9, 2018
5VPJ
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THE CRYSTAL STRUCTURE OF A THIOESTERAS FROM ACTINOMADURA VERRUCOSOSPORA.
Descriptor:Thioesterase, CHLORIDE ION, TETRAETHYLENE GLYCOL
Authors:Tan, K., Joachimiak, G., Endres, M., Phillips Jr., G.N., Joachmiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-05-05
Release date:2017-07-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The crystal structure of a thioesteras from Actinomadura verrucosospora.
To Be Published
5UQP
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THE CRYSTAL STRUCTURE OF CUPIN PROTEIN FROM RHODOCOCCUS JOSTII RHA1
Descriptor:Cupin, ZINC ION, CHLORIDE ION, ...
Authors:Tan, K., Li, H., Clancy, S., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-02-08
Release date:2017-02-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of cupin protein from Rhodococcus jostii RHA1
To Be Published
5UPQ
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ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP465 LIGAND
Descriptor:Acyl-CoA synthetase PtmA2, 5'-O-[(R)-{[(7beta,8alpha,9beta,10alpha,13alpha,16beta)-7,16-dihydroxy-18-oxokauran-18-yl]oxy}(hydroxy)phosphoryl]adenosine, SULFATE ION, ...
Authors:Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-02-03
Release date:2017-02-22
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018
5UPS
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ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP663 LIGAND
Descriptor:Acyl-CoA synthetase PtmA2, 5'-O-[(R)-hydroxy{[(7beta,8alpha,9beta,10alpha,11beta,13alpha)-7-hydroxy-19-oxo-11,16-epoxykauran-19-yl]oxy}phosphoryl]adenosine, SODIUM ION, ...
Authors:Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.-Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-02-03
Release date:2017-02-22
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018
5UPT
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ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP468 LIGAND
Descriptor:Acyl-CoA synthetase PtmA2, (7alpha,8alpha,10alpha,13alpha)-7,16-dihydroxykauran-18-oic acid, SULFATE ION, ...
Authors:Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-02-03
Release date:2017-02-22
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018
5UNC
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THE CRYSTAL STRUCTURE OF PHOSPHOENOLPYRUVATE PHOSPHOMUTASE FROM STREPTOMYCES PLATENSIS SUBSP. ROSACEUS
Descriptor:PHOSPHOENOLPYRUVATE PHOSPHOMUTASE, L(+)-TARTARIC ACID, XYLOPYRANOSE, ...
Authors:Tan, K., Hatzos-Skintges, C., Endres, M., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-01-30
Release date:2017-02-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:The crystal structure of PHOSPHOENOLPYRUVATE PHOSPHOMUTASE from Streptomyces platensis subsp. rosaceus
To Be Published
5UMP
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CRYSTAL STRUCTURE OF TNMS3, AN ANTIBIOTIC BINDING PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMQ
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CRYSTAL STRUCTURE OF TNMS1, AN ANTIBIOTIC BINDING PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMW
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CRYSTAL STRUCTURE OF TNMS2, AN ANTIBIOTIC BINDING PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMX
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH RIBOFLAVIN
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMY
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TIANCIMYCIN
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, (1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., SHen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UJP
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THE CRYSTAL STRUCTURE OF A GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Tan, K., Li, H., Endres, M., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-01-18
Release date:2017-02-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234
To Be Published
5UID
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THE CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE TLMJ FROM STREPTOALLOTEICHUS HINDUSTANUS
Descriptor:Aminotransferase TlmJ, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Tan, K., Bigelow, L., Bearden, J., Phillips Jr., G.N., Joachmiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2017-01-13
Release date:2017-02-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:The crystal structure of an aminotransferase TlmJ from Streptoalloteichus hindustanus.
To Be Published
5MG0
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STRUCTURE OF PAS-GAF FRAGMENT OF DEINOCOCCUS PHYTOCHROME BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, NICKEL (II) ION, ...
Authors:Burgie, E.S., Fuller, F.D., Gul, S., Miller, M.D., Young, I.D., Brewster, A.S., Clinger, J., Aller, P., Braeuer, P., Hutchison, C., Alonso-Mori, R., Kern, J., Yachandra, V.K., Yano, J., Sauter, N.K., Phillips Jr., G.N., Vierstra, R.D., Orville, A.M.
Deposit date:2016-11-20
Release date:2017-02-22
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers.
Nat. Methods, 14, 2017