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8TIM
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TRIOSE PHOSPHATE ISOMERASE
Descriptor:TRIOSE PHOSPHATE ISOMERASE, SULFATE ION
Authors:Artymiuk, P.J., Taylor, W.R., Phillips, D.C.
Deposit date:1998-08-25
Release date:1999-02-16
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Triose Phosphate Isomerase
To be Published
1LYZ
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REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Diamond, R., Phillips, D.C., Blake, C.C.F., North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
2LYZ
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REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Diamond, R., Phillips, D.C., Blake, C.C.F., North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
3LYZ
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REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Diamond, R., Phillips, D.C., Blake, C.C.F., North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
4LYZ
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REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Diamond, R., Phillips, D.C., Blake, C.C.F., North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
5LYZ
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REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Diamond, R., Phillips, D.C., Blake, C.C.F., North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
6LYZ
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REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Diamond, R., Phillips, D.C., Blake, C.C.F., North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
1TIM
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STRUCTURE OF TRIOSE PHOSPHATE ISOMERASE FROM CHICKEN MUSCLE
Descriptor:TRIOSEPHOSPHATE ISOMERASE
Authors:Banner, D.W., Bloomer, A.C., Petsko, G.A., Phillips, D.C., Wilson, I.A.
Deposit date:1976-09-01
Release date:1976-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomic coordinates for triose phosphate isomerase from chicken muscle.
Biochem.Biophys.Res.Commun., 72, 1976
1ALC
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REFINED STRUCTURE OF BABOON ALPHA-LACTALBUMIN AT 1.7 ANGSTROMS RESOLUTION. COMPARISON WITH C-TYPE LYSOZYME
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Acharya, K.R., Stuart, D.I., Phillips, D.C.
Deposit date:1989-08-14
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Refined structure of baboon alpha-lactalbumin at 1.7 A resolution. Comparison with C-type lysozyme.
J.Mol.Biol., 208, 1989
1HEW
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REFINEMENT OF AN ENZYME COMPLEX WITH INHIBITOR BOUND AT PARTIAL OCCUPANCY. HEN EGG-WHITE LYSOZYME AND TRI-N-ACETYLCHITOTRIOSE AT 1.75 ANGSTROMS RESOLUTION
Descriptor:HEN EGG WHITE LYSOZYME, N-ACETYL-D-GLUCOSAMINE
Authors:Cheetham, J.C., Artymiuk, P.J., Phillips, D.C.
Deposit date:1992-01-20
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Refinement of an enzyme complex with inhibitor bound at partial occupancy. Hen egg-white lysozyme and tri-N-acetylchitotriose at 1.75 A resolution.
J.Mol.Biol., 224, 1992
5LYT
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COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Dewan, J.C., Young, A.C.M., Tilton, R.F.
Deposit date:1992-03-20
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparison of Radiation-Induced Decay and Structure Refinement from X-Ray Data Collected from Lysozyme Crystals at Low and Ambient Temperatures
J.Appl.Crystallogr., 26, 1993
6LYT
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COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Dewan, J.C., Young, A.C.M., Tilton, R.F.
Deposit date:1992-03-20
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparison of Radiation-Induced Decay and Structure Refinement from X-Ray Data Collected from Lysozyme Crystals at Low and Ambient Temperatures
J.Appl.Crystallogr., 26, 1993
8LYZ
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AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Beddell, C.R., Blake, C.C.F., Oatley, S.J.
Deposit date:1977-09-16
Release date:1977-10-24
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An x-ray study of the structure and binding properties of iodine-inactivated lysozyme.
J.Mol.Biol., 97, 1975
1F6R
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CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN
Authors:Chrysina, E.D., Brew, K., Acharya, K.R.
Deposit date:2000-06-23
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions.
J.Biol.Chem., 275, 2000
1F6S
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CRYSTAL STRUCTURE OF BOVINE ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Chrysina, E.D., Brew, K., Acharya, K.R.
Deposit date:2000-06-23
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions.
J.Biol.Chem., 275, 2000
4LVT
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BCL_2-NAVITOCLAX (ABT-263) COMPLEX
Descriptor:Apoptosis regulator Bcl-2, 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide
Authors:Park, C.H.
Deposit date:2013-07-26
Release date:2013-08-14
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
NAT.MED. (N.Y.), 19, 2013
4LXD
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BCL_2-NAVITOCLAX ANALOG (WITHOUT THIOPHENYL) COMPLEX
Descriptor:Apoptosis regulator Bcl-2, 4-(4-{[4-(4-chlorophenyl)-5,6-dihydro-2H-pyran-3-yl]methyl}piperazin-1-yl)-N-{[3-nitro-4-(tetrahydro-2H-pyran-4-ylamino)phenyl]sulfonyl}benzamide
Authors:Park, C.H.
Deposit date:2013-07-29
Release date:2013-08-14
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
NAT.MED. (N.Y.), 19, 2013
4MAN
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BCL_2-NAVITOCLAX ANALOG (WITH INDOLE) COMPLEX
Descriptor:Apoptosis regulator Bcl-2, 4-[4-({4'-chloro-3-[2-(dimethylamino)ethoxy]biphenyl-2-yl}methyl)piperazin-1-yl]-2-(1H-indol-5-yloxy)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)benzamide
Authors:Park, C.H.
Deposit date:2013-08-16
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
NAT.MED. (N.Y.), 19, 2013
1HFX
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1HFY
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1HFZ
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1HML
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ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION, ZINC ION, ...
Authors:Ren, J., Stuart, D.I., Acharya, K.R.
Deposit date:1994-09-29
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Alpha-lactalbumin possesses a distinct zinc binding site.
J.Biol.Chem., 268, 1993
4QVX
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DISCOVERY OF A POTENT AND SELECTIVE BCL-XL INHIBITOR THAT DEMONSTRATES THROMBOCYTOPENIA AND INHIBITS TUMOR GROWTH IN VIVO
Descriptor:Bcl-2-like protein 1, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-(3-{4-[3-(dimethylamino)prop-1-yn-1-yl]-2-fluorophenoxy}propyl)-1,3-thiazole-4-carboxylic acid
Authors:Park, C.H.
Deposit date:2014-07-16
Release date:2015-07-22
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.
ACS MED.CHEM.LETT., 5, 2014
5VKC
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CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH A BIM COMPETITIVE INHIBITOR
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 7-(3-{[4-(4-acetylpiperazin-1-yl)phenoxy]methyl}-1,5-dimethyl-1H-pyrazol-4-yl)-3-{3-[(naphthalen-1-yl)oxy]propyl}-1-[(pyridin-3-yl)methyl]-1H-indole-2-carboxylic acid, ZINC ION
Authors:Judge, R.A., Souers, A.J.
Deposit date:2017-04-21
Release date:2017-05-03
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J. Med. Chem., 58, 2015
6B4L
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CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH A BIM COMPETITIVE INHIBITOR
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 3-{3-[(naphthalen-1-yl)oxy]propyl}-1H-indole-2-carboxylic acid
Authors:Judge, R.A., Souers, A.J.
Deposit date:2017-09-26
Release date:2017-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J. Med. Chem., 58, 2015
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