Author results

6BJQ
  • Download 6bjq
  • View 6bjq
Molmil generated image of 6bjq
EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO GLUCURONIC ACID
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase, BETA-D-GLUCOPYRANURONIC ACID
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-06
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BJW
  • Download 6bjw
  • View 6bjw
Molmil generated image of 6bjw
EUBACTERIUM ELIGENS BETA-GLUCURONIDASE
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-07
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BO6
  • Download 6bo6
  • View 6bo6
Molmil generated image of 6bo6
EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO UNC4917 GLUCURONIC ACID CONJUGATE
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase, 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-18
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6D4O
  • Download 6d4o
  • View 6d4o
Molmil generated image of 6d4o
EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO AN AMOXAPINE-GLUCURONIDE CONJUGATE
Descriptor:Beta-glucuronidase, (5aR,9aR)-2-chloro-11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5a,6,9,9a-tetrahydrodibenzo[b,f][1,4]oxazepine, CHLORIDE ION, ...
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2018-04-18
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6MVF
  • Download 6mvf
  • View 6mvf
Molmil generated image of 6mvf
CRYSTAL STRUCTURE OF FMN-BINDING BETA-GLUCURONIDASE FROM FACAELIBACTERIUM PRAUSNITZII L2-6
Descriptor:Beta-galactosidase/beta-glucuronidase, FLAVIN MONONUCLEOTIDE
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
6MVG
  • Download 6mvg
  • View 6mvg
Molmil generated image of 6mvg
CRYSTAL STRUCTURE OF FMN-BINDING BETA-GLUCURONIDASE FROM RUMINOCOCCUS GNAVUS
Descriptor:beta-glucuronidase, FLAVIN MONONUCLEOTIDE, CALCIUM ION
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
6MVH
  • Download 6mvh
  • View 6mvh
Molmil generated image of 6mvh
CRYSTAL STRUCTURE OF FMN-BINDING BETA-GLUCURONIDASE FROM ROSEBURIA HOMINIS
Descriptor:Beta-galactosidase, CALCIUM ION, FLAVIN MONONUCLEOTIDE
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
6AZ6
  • Download 6az6
  • View 6az6
Molmil generated image of 6az6
STREPTOCOCCUS AGALACTIAE GNTR
Descriptor:GntR family transcriptional regulator
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2017-09-10
Release date:2017-12-20
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D1N
  • Download 6d1n
  • View 6d1n
Molmil generated image of 6d1n
APO STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1
Descriptor:Beta-galactosidase/beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D1P
  • Download 6d1p
  • View 6d1p
Molmil generated image of 6d1p
APO STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 3
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D41
  • Download 6d41
  • View 6d41
Molmil generated image of 6d41
BACTERIODES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO D-GLUCARO-1,5-LACTONE
Descriptor:Beta-galactosidase/beta-glucuronidase, GLYCEROL, CHLORIDE ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-17
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D50
  • Download 6d50
  • View 6d50
Molmil generated image of 6d50
BACTEROIDES UNIFORMS BETA-GLUCURONIDASE 2 BOUND TO D-GLUCARO-1,5-LACTONE
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, CALCIUM ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-19
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D6W
  • Download 6d6w
  • View 6d6w
Molmil generated image of 6d6w
BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO GLUCURONATE
Descriptor:Beta-galactosidase/beta-glucuronidase, D-GLUCURONIC ACID, GLYCEROL, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-23
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D7F
  • Download 6d7f
  • View 6d7f
Molmil generated image of 6d7f
BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO THIOPHENYL-BETA-D-GLUCURONIDE
Descriptor:Beta-galactosidase/beta-glucuronidase, phenyl 1-thio-beta-D-glucopyranosiduronic acid, CHLORIDE ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-24
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D89
  • Download 6d89
  • View 6d89
Molmil generated image of 6d89
BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 WITH N-TERMINAL LOOP DELETION
Descriptor:Beta-galactosidase/beta-glucuronidase, CITRIC ACID, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8G
  • Download 6d8g
  • View 6d8g
Molmil generated image of 6d8g
D341A D367A CALCIUM BINDING MUTANT OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 2
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8K
  • Download 6d8k
  • View 6d8k
Molmil generated image of 6d8k
BACTEROIDES MULTIPLE SPECIES BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolase family 2, sugar binding domain protein
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6ED2
  • Download 6ed2
  • View 6ed2
Molmil generated image of 6ed2
FAECALIBACTERIUM PRAUSNITZII BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolase family 2, TIM barrel domain protein, GLYCEROL, ...
Authors:Pellock, S.J., Biernat, K.A., Redinbo, M.R.
Deposit date:2018-08-08
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6NCW
  • Download 6ncw
  • View 6ncw
Molmil generated image of 6ncw
CRYSTAL STRUCTURE OF A GH2 BETA-GALACTURONIDASE FROM EISENBERGIELLA TAYI BOUND TO GLYCEROL
Descriptor:Beta-galacturonidase, CHLORIDE ION, GLYCEROL
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCX
  • Download 6ncx
  • View 6ncx
Molmil generated image of 6ncx
CRYSTAL STRUCTURE OF GH2 BETA-GALACTURONIDASE FROM EISENBERGIELLA TAYI BOUND TO GALACTURONATE
Descriptor:Beta-galacturonidase, ALPHA-D-GALACTOPYRANURONIC ACID, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCY
  • Download 6ncy
  • View 6ncy
Molmil generated image of 6ncy
CRYSTAL STRUCTURE OF HYBRID BETA-GLUCURONIDASE/BETA-GALACTURONIDASE FROM FUSICATENIBACTER SACCHARIVORANS
Descriptor:Beta-glucuronidase, NICKEL (II) ION, GLYCEROL, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCZ
  • Download 6ncz
  • View 6ncz
Molmil generated image of 6ncz
CRYSTAL STRUCTURE OF HYBRID BETA-GLUCURONIDASE/BETA-GALACTURONIDASE FROM FUSICATENIBACTER SACCHARIVORANS BOUND TO PHENYL-THIO-BETA-D-GLUCURONIDE
Descriptor:Beta-glucuronidase, phenyl 1-thio-beta-D-glucopyranosiduronic acid, GLYCEROL
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6AYH
  • Download 6ayh
  • View 6ayh
Molmil generated image of 6ayh
SALMONELLA ENTERICA GUSR
Descriptor:TetR family transcriptional regulator, GLYCEROL, 4-nitrophenyl beta-D-glucopyranosiduronic acid
Authors:Little, M.S., Pellock, S.J.
Deposit date:2017-09-08
Release date:2017-12-20
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6AYI
  • Download 6ayi
  • View 6ayi
Molmil generated image of 6ayi
ESCHERICHIA COLI GUSR
Descriptor:HTH-type transcriptional regulator UidR, 4-nitrophenyl beta-D-glucopyranosiduronic acid
Authors:Little, M.S., Pellock, S.J.
Deposit date:2017-09-08
Release date:2017-12-20
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ECA
  • Download 6eca
  • View 6eca
Molmil generated image of 6eca
LACTOBACILLUS RHAMNOSUS BETA-GLUCURONIDASE
Descriptor:Beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Biernat, K.A., Pellock, S.J., Bhatt, A.P., Bivins, M.M., Walton, W.G., Tran, B.N.T., Wei, L., Snider, M.C., Cesmat, A.P., Tripathy, A., Erie, D.A., Redinbo, M.R.R.
Deposit date:2018-08-07
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.853 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
<12>