2FU4
| Crystal Structure of the DNA binding domain of E.coli FUR (Ferric Uptake Regulator) | Descriptor: | CADMIUM ION, CHLORIDE ION, Ferric uptake regulation protein, ... | Authors: | Pecqueur, L, D'Autreaux, B, Dupuy, J, Nicolet, Y, Jacquamet, L, Brutscher, B, Michaud-Soret, I, Bersch, B. | Deposit date: | 2006-01-26 | Release date: | 2006-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural changes of Escherichia coli ferric uptake regulator during metal-dependent dimerization and activation explored by NMR and X-ray crystallography J.Biol.Chem., 281, 2006
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4DRX
| GTP-Tubulin in complex with a DARPIN | Descriptor: | Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Pecqueur, L, Gigant, B, Knossow, M. | Deposit date: | 2012-02-17 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end. Proc.Natl.Acad.Sci.USA, 109, 2012
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4DUI
| DARPIN D1 binding to tubulin beta chain (not in complex) | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1 | Authors: | Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M. | Deposit date: | 2012-02-22 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | An Anti-Tubulin Darpin Caps the Microtubule Plus-End To be Published
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4K22
| Structure of the C-terminal truncated form of E.Coli C5-hydroxylase UBII involved in ubiquinone (Q8) biosynthesis | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Pecqueur, L, Lombard, M, Golinelli-pimpaneau, B, Fontecave, M. | Deposit date: | 2013-04-07 | Release date: | 2013-05-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | ubiI, a New Gene in Escherichia coli Coenzyme Q Biosynthesis, Is Involved in Aerobic C5-hydroxylation. J.Biol.Chem., 288, 2013
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8CNZ
| mmLarE-[4Fe-4S] phased by Fe-SAD | Descriptor: | CHLORIDE ION, IODIDE ION, IRON/SULFUR CLUSTER, ... | Authors: | Pecqueur, L, Zecchin, P, Golinelli-Pimpaneau, B. | Deposit date: | 2023-02-24 | Release date: | 2024-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024
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6QYH
| Structure of Apo HPAB from E.coli | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-hydroxyphenylacetate 3-monooxygenase oxygenase component, CALCIUM ION, ... | Authors: | Pecqueur, L, Lombard, M, Deng, Y, Fontecave, M. | Deposit date: | 2019-03-09 | Release date: | 2019-06-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural and Functional Characterization of 4-Hydroxyphenylacetate 3-Hydroxylase from Escherichia coli. Chembiochem, 21, 2020
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6QYI
| Structure of HPAB from E.coli in complex with FAD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-hydroxyphenylacetate 3-monooxygenase oxygenase component, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pecqueur, L, Lombard, M, Deng, Y, Fontecave, M. | Deposit date: | 2019-03-09 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Characterization of 4-Hydroxyphenylacetate 3-Hydroxylase from Escherichia coli. Chembiochem, 21, 2020
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8B02
| Crystal structure of the dsRBD domain of tRNA-dihydrouridine(20) synthase from Amphimedon queenslandica | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, DRBM domain-containing protein, ... | Authors: | Pecqueur, L, Faivre, B, Hamdane, D. | Deposit date: | 2022-09-07 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.676 Å) | Cite: | Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family. Biomolecules, 12, 2022
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6Z96
| [4Fe-4S]-dependent thiouracil desulfidase TudS (DUF523Vcz) soaked with 4-thiouracil (12.65 keV, 7.125 keV (Fe-SAD) and 6.5 keV (S-SAD) data) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, HYDROSULFURIC ACID, ... | Authors: | Pecqueur, L, Zhou, J, Fontecave, M, Golinelli-Pimpaneau, B. | Deposit date: | 2020-06-03 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.327 Å) | Cite: | Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil. Angew.Chem.Int.Ed.Engl., 60, 2021
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6Z92
| [4Fe-4S]-dependent thiouracil desulfidase TudS (DUF523Vcz) solved by Fe-SAD phasing | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DUF523 domain-containing protein, ... | Authors: | Pecqueur, L, Zhou, J, Fontecave, M, Golinelli-Pimpaneau, B. | Deposit date: | 2020-06-03 | Release date: | 2020-09-30 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.067 Å) | Cite: | Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil. Angew.Chem.Int.Ed.Engl., 60, 2021
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6Z93
| [4Fe-4S]-dependent thiouracil desulfidase TudS (DUF523Vcz) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | Authors: | Pecqueur, L, Zhou, J, Fontecave, M, Golinelli-Pimpaneau, B. | Deposit date: | 2020-06-03 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.505 Å) | Cite: | Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil. Angew.Chem.Int.Ed.Engl., 60, 2021
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6Z94
| [4Fe-4S]-dependent thiouracil desulfidase TudS (DUF523Vcz)(S-SAD data) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DUF523 domain-containing protein, ... | Authors: | Pecqueur, L, Zhou, J, Fontecave, M, Golinelli-Pimpaneau, B. | Deposit date: | 2020-06-03 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.759 Å) | Cite: | Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil. Angew.Chem.Int.Ed.Engl., 60, 2021
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6ZW9
| [4Fe-4S]-dependent thiouracil desulfidase TudS (DUF523Vcz) soaked with 4-thiouracil (S-SAD data) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DUF523 domain-containing protein, ... | Authors: | Pecqueur, L, Zhou, J, Fontecave, M, Golinelli-Pimpaneau, B. | Deposit date: | 2020-07-28 | Release date: | 2020-09-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.759 Å) | Cite: | Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil. Angew.Chem.Int.Ed.Engl., 60, 2021
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5FRH
| Solution structure of oxidised RsrA | Descriptor: | ANTI-SIGMA FACTOR RSRA | Authors: | Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C. | Deposit date: | 2015-12-17 | Release date: | 2016-08-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core. Nat.Commun., 7, 2016
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4WFS
| Crystal Structure of tRNA-dihydrouridine(20) synthase catalytic domain | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | Authors: | Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. | Deposit date: | 2014-09-17 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | An extended dsRBD is required for post-transcriptional modification in human tRNAs. Nucleic Acids Res., 43, 2015
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4WFT
| Crystal structure of tRNA-dihydrouridine(20) synthase dsRBD domain | Descriptor: | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | Authors: | Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. | Deposit date: | 2014-09-17 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An extended dsRBD is required for post-transcriptional modification in human tRNAs. Nucleic Acids Res., 43, 2015
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6EI8
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6EZA
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Bou-Nader, C, Bregeon, D, Pecqueur, L, Vincent, G, Fontecave, M, Hamdane, D. | Deposit date: | 2017-11-14 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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6EZB
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain Q305K mutant | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, SULFATE ION, ... | Authors: | Bou-Nader, C, Bregeon, D, Pecqueur, L, Fontecave, M, Hamdane, D. | Deposit date: | 2017-11-14 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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5KH0
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5LAD
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8CP3
| Apo-LarE in complex with AMP-PNP | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, NAD_synthase domain-containing protein, ... | Authors: | Zecchin, P, Pecqueur, L, Golinelli-Pimpaneau, B. | Deposit date: | 2023-03-01 | Release date: | 2024-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024
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8CP4
| [4Fe-4S] cluster containing LarE in complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | Authors: | Zecchin, P, Pecqueur, L, Golinelli-Pimpaneau, B. | Deposit date: | 2023-03-01 | Release date: | 2024-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024
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7NDZ
| ThyX reconstituted with N5-carbinolamine flavin | Descriptor: | DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ... | Authors: | Bou-Nader, C, Pecqueur, L, Hamdane, D. | Deposit date: | 2021-02-02 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An enzymatic activation of formaldehyde for nucleotide methylation. Nat Commun, 12, 2021
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7NDW
| ThyX-FADH2 soaked with 20 mM Formaldehyde | Descriptor: | DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ... | Authors: | Bou-Nader, C, Pecqueur, L, Hamdane, D. | Deposit date: | 2021-02-02 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An enzymatic activation of formaldehyde for nucleotide methylation. Nat Commun, 12, 2021
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