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1M9P
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CRYSTALLINE HUMAN CARBONMONOXY HEMOGLOBIN C EXHIBITS THE R2 QUATERNARY STATE AT NEUTRAL PH IN THE PRESENCE OF POLYETHYLENE GLYCOL: THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE
Descriptor:Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Patskovska, L.N., Patskovsky, Y.V., Almo, S.C., Hirsch, R.E.
Deposit date:2002-07-29
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000.
Acta Crystallogr.,Sect.D, 61, 2005
1NEJ
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CRYSTALLINE HUMAN CARBONMONOXY HEMOGLOBIN S (LIGANDED SICKLE CELL HEMOGLOBIN) EXHIBITS THE R2 QUATERNARY STATE AT NEUTRAL PH IN THE PRESENCE OF POLYETHYLENE GLYCOL: THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE
Descriptor:Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Patskovska, L.N., Patskovsky, Y.V., Almo, S.C., Hirsch, R.E.
Deposit date:2002-12-11
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000.
Acta Crystallogr.,Sect.D, 61, 2005
1XW5
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18)COMPLEXED WITH GLUTATHIONE, MONOCLINIC CRYSTAL FORM
Descriptor:Glutathione S-transferase Mu 2, GLUTATHIONE
Authors:Patskovska, L.N., Patskovsky, Y.V., Almo, S.C., Listowsky, I.
Deposit date:2004-10-29
Release date:2004-11-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Perturbation of the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
2GTU
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LIGAND-FREE HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18), MONOCLINIC CRYSTAL FORM
Descriptor:GLUTATHIONE S-TRANSFERASE
Authors:Patskovska, L.N., Fedorov, A.A., Patskovsky, Y.V., Almo, S.C., Listowsky, I.
Deposit date:1998-05-26
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The enhanced affinity for thiolate anion and activation of enzyme-bound glutathione is governed by an arginine residue of human Mu class glutathione S-transferases.
J.Biol.Chem., 275, 2000
1YJ6
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE M1A-1A COMPLEXED WITH GLUTATHIONYL-ZINC-TRIHYDROXIDE
Descriptor:Glutathione S-transferase Mu 1, ZINC ION, GLUTATHIONE
Authors:Patskovsky, Y.V., Patskovska, L.N., Listowsky, I., Almo, S.C.
Deposit date:2005-01-13
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human Glutathione S-Transferase M1A-1A Catalyzes Formation of Gsh-Metal Complexes
To be Published
1YKC
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) COMPLEXED WITH GLUTATHIONE-DISULFIDE
Descriptor:Glutathione S-transferase Mu 2, OXIDIZED GLUTATHIONE DISULFIDE
Authors:Patskovsky, Y.V., Patskovska, L.N., Listowsky, I., Almo, S.C.
Deposit date:2005-01-17
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective Inhibitors of Prostaglandin Synthase activity of human glutathione S-transferase M2-2
To be Published
1GTU
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LIGAND-FREE HUMAN GLUTATHIONE S-TRANSFERASE M1A-1A
Descriptor:GLUTATHIONE S-TRANSFERASE
Authors:Patskovsky, Y.V., Patskovska, L.N., Listowsky, I.
Deposit date:1998-06-11
Release date:1999-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Functions of His107 in the catalytic mechanism of human glutathione S-transferase hGSTM1a-1a.
Biochemistry, 38, 1999
3GTU
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LIGAND-FREE HETERODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M2-3 (EC 2.5.1.18), MONOCLINIC CRYSTAL FORM
Descriptor:GLUTATHIONE S-TRANSFERASE
Authors:Patskovsky, Y.V., Patskovska, L.N., Listowsky, I.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.
Biochemistry, 38, 1999
4GTU
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LIGAND-FREE HOMODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M4-4
Descriptor:GLUTATHIONE S-TRANSFERASE
Authors:Patskovsky, Y.V., Patskovska, L.N., Listowsky, I.
Deposit date:1999-05-12
Release date:2000-01-14
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.
Biochemistry, 38, 1999
1XW6
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1.9 ANGSTROM RESOLUTION STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE M1A-1A COMPLEXED WITH GLUTATHIONE
Descriptor:Glutathione S-transferase Mu 1, GLUTATHIONE
Authors:Patskovsky, Y., Patskovska, L., Almo, S.C., Listowsky, I.
Deposit date:2004-10-29
Release date:2004-12-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
1XWK
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2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE M1A-1A COMPLEXED WITH GLUTATHIONYL-S-DINITROBENZENE
Descriptor:Glutathione S-transferase Mu 1, GLUTATHIONE S-(2,4 DINITROBENZENE)
Authors:Patskovsky, Y., Patskovska, L., Almo, S.C., Listowsky, I.
Deposit date:2004-11-01
Release date:2004-12-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
2F3M
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STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE M1A-1A COMPLEXED WITH 1-(S-(GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXADIENATE ANION
Descriptor:Glutathione S-transferase Mu 1, 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE
Authors:Patskovsky, Y., Patskovska, L., Almo, S.C., Listowsky, I.
Deposit date:2005-11-21
Release date:2006-04-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
2AB6
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) COMPLEXED WITH S-METHYLGLUTATHIONE
Descriptor:Glutathione S-transferase Mu 2, L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE
Authors:Patskovsky, Y., Almo, S.C., Listowsky, I.
Deposit date:2005-07-14
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Perturbations in the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published