1NEJ

Crystalline Human Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Exhibits The R2 Quaternary State At Neutral pH In The Presence Of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure

Summary for 1NEJ

Entry DOI	10.2210/pdb1nej/pdb
Related	1BBB 1HHO 1K1K 1M9P 1RVW
Descriptor	Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	mutant human hemoglobin s[betae6v]; r2 quaternary state; human hemoglobin, oxygen storage-transport complex, oxygen storage/transport
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	64599.13
Authors	Patskovska, L.N.,Patskovsky, Y.V.,Almo, S.C.,Hirsch, R.E. (deposition date: 2002-12-11, release date: 2003-12-16, Last modification date: 2023-08-16)
Primary citation	Patskovska, L.N.,Patskovsky, Y.V.,Almo, S.C.,Hirsch, R.E. COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000. Acta Crystallogr.,Sect.D, 61:566-573, 2005 Cited by PubMed: 15858266 DOI: 10.1107/S0907444905004622 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation