2F3M
Structure of human GLUTATHIONE S-TRANSFERASE M1A-1A complexed with 1-(S-(GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXADIENATE ANION
Summary for 2F3M
| Entry DOI | 10.2210/pdb2f3m/pdb |
| Related | 1GTU 1XW6 1XWK |
| Descriptor | Glutathione S-transferase Mu 1, 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE (3 entities in total) |
| Functional Keywords | transferase, glutathione, conjugation, detoxification, cytosolic, dimer, active site, transition state analogue |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P09488 |
| Total number of polymer chains | 6 |
| Total formula weight | 157603.62 |
| Authors | Patskovsky, Y.,Patskovska, L.,Almo, S.C.,Listowsky, I. (deposition date: 2005-11-21, release date: 2006-04-25, Last modification date: 2023-08-23) |
| Primary citation | Patskovsky, Y.,Patskovska, L.,Almo, S.C.,Listowsky, I. Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a. Biochemistry, 45:3852-3862, 2006 Cited by PubMed: 16548513DOI: 10.1021/bi051823+ PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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