Author results

3JBL
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CRYO-EM STRUCTURE OF THE ACTIVATED NAIP2/NLRC4 INFLAMMASOME REVEALS NUCLEATED POLYMERIZATION
Descriptor:NLR family CARD domain-containing protein 4
Authors:Zhang, L., Chen, S., Ruan, J., Wu, J., Tong, A.B., Yin, Q., Li, Y., David, L., Lu, A., Wang, W.L., Marks, C., Ouyang, Q., Zhang, X., Mao, Y., Wu, H.
Deposit date:2015-09-05
Release date:2015-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
5T0C
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-15
Release date:2016-10-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0G
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0H
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S protease regulatory subunit 7, 26S protease regulatory subunit 4, 26S protease regulatory subunit 8, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0I
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S protease regulatory subunit 7, 26S protease regulatory subunit 4, 26S protease regulatory subunit 8, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0J
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STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME
Descriptor:26S proteasome non-ATPase regulatory subunit 2, Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, ...
Authors:Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VFO
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-08
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFP
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFQ
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFR
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFS
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:Proteasome subunit alpha type-6, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFT
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:13, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFU
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NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN THE ACTIVATED HUMAN 26S PROTEASOME
Descriptor:26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Zhu, Y., Wang, W.L., Yu, D., Ouyang, Q., Lu, Y., Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VGZ
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-12
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHF
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHH
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHI
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHJ
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHM
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHN
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHO
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHP
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHQ
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHR
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHS
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CONFORMATIONAL LANDSCAPE OF THE P28-BOUND HUMAN PROTEASOME REGULATORY PARTICLE
Descriptor:26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 8, ...
Authors:Lu, Y., Wu, J., Dong, Y., Chen, S., Sun, S., Ma, Y.B., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017