Author results

2KXX
  • Download 2kxx
  • View 2kxx
Molmil generated image of 2kxx
NMR STRUCTURE OF ESCHERICHIA COLI BAME, A LIPOPROTEIN COMPONENT OF THE BETA-BARREL ASSEMBLY MACHINERY COMPLEX
Descriptor:Small protein A
Authors:Kim, K., Okon, M., Escobar, E., Kang, H., McIntosh, L., Paetzel, M.
Deposit date:2010-05-13
Release date:2011-01-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of Escherichia coli BamE, a Lipoprotein Component of the beta-Barrel Assembly Machinery Complex.
Biochemistry, 50, 2011
2LQV
  • Download 2lqv
  • View 2lqv
Molmil generated image of 2lqv
YEBF
Descriptor:Protein yebF
Authors:Prehna, G., Zhang, G., Gong, X., Duszyk, M., Okon, M., Mcintosh, L.P., Weiner, J.H., Strynadka, N.C.J.
Deposit date:2012-03-16
Release date:2012-06-13
Last modified:2012-07-25
Method:SOLUTION NMR
Cite:A Protein Export Pathway Involving Escherichia coli Porins.
Structure, 20, 2012
2LV4
  • Download 2lv4
  • View 2lv4
Molmil generated image of 2lv4
ZIRS C-TERMINAL DOMAIN
Descriptor:Putative outer membrane or exported protein
Authors:Prehna, G., Li, Y., Stoynov, N., Okon, M., Vukovic, M., Mcintosh, L.P., Foster, L.J., Finlay, B., Strynadka, N.C.J.
Deposit date:2012-06-28
Release date:2012-08-22
Last modified:2012-10-10
Method:SOLUTION NMR
Cite:The zinc regulated antivirulence pathway of salmonella is a multiprotein immunoglobulin adhesion system.
J.Biol.Chem., 287, 2012
1T5M
  • Download 1t5m
  • View 1t5m
Molmil generated image of 1t5m
STRUCTURAL TRANSITIONS AS DETERMINANTS OF THE ACTION OF THE CALCIUM-DEPENDENT ANTIBIOTIC DAPTOMYCIN
Descriptor:DAPTOMYCIN, DECANOIC ACID
Authors:Jung, D., Rozek, A., Okon, M., Hancock, R.E.
Deposit date:2004-05-04
Release date:2004-08-31
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:Structural Transitions as Determinants of the Action of the Calcium-Dependent Antibiotic Daptomycin.
Chem.Biol., 11, 2004
1T5N
  • Download 1t5n
  • View 1t5n
Molmil generated image of 1t5n
STRUCTURAL TRANSITIONS AS DETERMINANTS OF CALCIUM-DEPENDENT ANTIBIOTIC DAPTOMYCIN
Descriptor:DAPTOMYCIN, DECANOIC ACID
Authors:Jung, D., Rozek, A., Okon, M., Hancock, R.E.
Deposit date:2004-05-04
Release date:2004-08-31
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:Structural Transitions as Determinants of the Action of the Calcium-Dependent Antibiotic Daptomycin.
Chem.Biol., 11, 2004
2MD5
  • Download 2md5
  • View 2md5
Molmil generated image of 2md5
STRUCTURE OF UNINHIBITED ETV6 ETS DOMAIN
Descriptor:Transcription factor ETV6
Authors:De, S., Mcintosh, L.P., Chan, A.C., Coyne, H.J., Okon, M., Graves, B.J., Murphy, M.E.
Deposit date:2013-08-29
Release date:2013-12-25
Last modified:2014-04-02
Method:SOLUTION NMR
Cite:Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
3VZJ
  • Download 3vzj
  • View 3vzj
Molmil generated image of 3vzj
CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) E172H MUTANT
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Ludwiczek, M.L., D'Angelo, I., Yalloway, G.N., Okon, M., Nielsen, J.E., Strynadka, N.C., Withers, S.G., McIntosh, L.P.
Deposit date:2012-10-14
Release date:2013-05-08
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZK
  • Download 3vzk
  • View 3vzk
Molmil generated image of 3vzk
CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) N35E MUTANT
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Ludwiczek, M.L., D'Angelo, I., Yalloway, G.N., Okon, M., Nielsen, J.E., Strynadka, N.C., Withers, S.G., McIntosh, L.P.
Deposit date:2012-10-14
Release date:2013-05-08
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZL
  • Download 3vzl
  • View 3vzl
Molmil generated image of 3vzl
CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) N35H MUTANT
Descriptor:Endo-1,4-beta-xylanase, SULFATE ION
Authors:Ludwiczek, M.L., D'Angelo, I., Yalloway, G.N., Okon, M., Nielsen, J.E., Strynadka, N.C., Withers, S.G., McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZM
  • Download 3vzm
  • View 3vzm
Molmil generated image of 3vzm
CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) E172H MUTANT WITH GLU78 COVALENTLY BONDED TO 2-DEOXY-2-FLUORO-XYLOBIOSE
Descriptor:Endo-1,4-beta-xylanase, 1,2-DEOXY-2-FLUORO-XYLOPYRANOSE, BETA-D-XYLOPYRANOSE
Authors:Ludwiczek, M.L., D'Angelo, I., Yalloway, G.N., Okon, M., Nielsen, J.E., Strynadka, N.C., Withers, S.G., McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZN
  • Download 3vzn
  • View 3vzn
Molmil generated image of 3vzn
CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) N35E MUTANT WITH GLU78 COVALENTLY BONDED TO 2-DEOXY-2-FLUORO-XYLOBIOSE
Descriptor:Endo-1,4-beta-xylanase, 1,2-DEOXY-2-FLUORO-XYLOPYRANOSE, BETA-D-XYLOPYRANOSE, ...
Authors:Ludwiczek, M.L., D'Angelo, I., Yalloway, G.N., Okon, M., Nielsen, J.E., Strynadka, N.C., Withers, S.G., McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZO
  • Download 3vzo
  • View 3vzo
Molmil generated image of 3vzo
CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) N35H MUTANT WITH GLU78 COVALENTLY BONDED TO 2-DEOXY-2-FLUORO-XYLOBIOSE
Descriptor:Endo-1,4-beta-xylanase, 1,2-DEOXY-2-FLUORO-XYLOPYRANOSE, BETA-D-XYLOPYRANOSE, ...
Authors:Ludwiczek, M.L., D'Angelo, I., Yalloway, G.N., Okon, M., Nielsen, J.E., Strynadka, N.C., Withers, S.G., McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
4MHG
  • Download 4mhg
  • View 4mhg
Molmil generated image of 4mhg
CRYSTAL STRUCTURE OF ETV6 BOUND TO A SPECIFIC DNA SEQUENCE
Descriptor:Specific 14 bp DNA, Complementary Specific 14 bp DNA, Transcription factor ETV6
Authors:Chan, A.C., De, S., Coyne III, H.J., Okon, M., Murphy, M.E., Graves, B.J., McIntosh, L.P.
Deposit date:2013-08-29
Release date:2014-01-08
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
6CAH
  • Download 6cah
  • View 6cah
Molmil generated image of 6cah
NMR-BASED STRUCTURE OF THE FHA-2 DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS ABC TRANSPORTER RV1747
Descriptor:ABC transporter ATP-binding/permease protein Rv1747
Authors:Heinkel, F., Okon, M., Gsponer, J., McIntosh, L.P.
Deposit date:2018-01-30
Release date:2018-06-20
Last modified:2018-07-18
Method:SOLUTION NMR
Cite:Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Structure, 26, 2018
6DA1
  • Download 6da1
  • View 6da1
Molmil generated image of 6da1
ETS1 IN COMPLEX WITH SYNTHETIC SRR MIMIC
Descriptor:Protein C-ets-1, serine-rich region (SRR) peptide, SULFATE ION
Authors:Perez-Borrajero, C., Okon, M., Lin, C.S., Scheu, K., Murphy, M.E.P., Graves, B.J., McIntosh, L.P.
Deposit date:2018-05-01
Release date:2019-01-16
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.000127 Å)
Cite:The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
J. Mol. Biol., 431, 2019
6DAT
  • Download 6dat
  • View 6dat
Molmil generated image of 6dat
ETS1 IN COMPLEX WITH SYNTHETIC SRR MIMIC
Descriptor:Protein C-ets-1, serine-rich region (SRR) peptide, SULFATE ION
Authors:Perez-Borrajero, C., Okon, M., Lin, C.S., Scheu, K., Murphy, M.E.P., Graves, B.J., McIntosh, L.P.
Deposit date:2018-05-02
Release date:2019-01-16
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.350026 Å)
Cite:The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
J. Mol. Biol., 431, 2019
2JW1
  • Download 2jw1
  • View 2jw1
Molmil generated image of 2jw1
STRUCTURAL CHARACTERIZATION OF THE TYPE III PILOTIN-SECRETIN INTERACTION IN SHIGELLA FLEXNERI BY NMR SPECTROSCOPY
Descriptor:Lipoprotein mxiM, Outer membrane protein mxiD
Authors:Okon, M.S., Lario, P.I., Creagh, L., Jung, Y.M.T., Maurelli, A.T., Strynadka, N.C.J., McIntosh, L.P.
Deposit date:2007-10-02
Release date:2008-09-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of the Type-III Pilot-Secretin Complex from Shigella flexneri
Structure, 16, 2008
3LB9
  • Download 3lb9
  • View 3lb9
Molmil generated image of 3lb9
CRYSTAL STRUCTURE OF THE B. CIRCULANS CPA123 CIRCULAR PERMUTANT
Descriptor:Endo-1,4-beta-xylanase
Authors:D'Angelo, I., Reitinger, S., Ludwiczek, M., Strynadka, N., Withers, S.G., Mcintosh, L.P.
Deposit date:2010-01-08
Release date:2010-03-23
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Circular permutation of Bacillus circulans xylanase: a kinetic and structural study.
Biochemistry, 49, 2010
6CCD
  • Download 6ccd
  • View 6ccd
Molmil generated image of 6ccd
THE CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS RV1747 FHA-1
Descriptor:ABC transporter ATP-binding/permease protein Rv1747, SULFATE ION
Authors:Gay, L.M., Gee, C.L., Alber, T.
Deposit date:2018-02-06
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Structure, 26, 2018
3IET
  • Download 3iet
  • View 3iet
Molmil generated image of 3iet
CRYSTAL STRUCTURE OF 237MAB WITH ANTIGEN
Descriptor:Immunoglobulin light chain (IgG2a), Immunoglobulin heavy chain (IgG2a), Podoplanin, ...
Authors:Brooks, C.L., Evans, S.V., Borisova, S.N.
Deposit date:2009-07-23
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody recognition of a unique tumor-specific glycopeptide antigen.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IF1
  • Download 3if1
  • View 3if1
Molmil generated image of 3if1
CRYSTAL STRUCTURE OF 237MAB IN COMPLEX WITH A GALNAC
Descriptor:Immunoglobulin light chain (IgG2a), Immunoglobulin heavy chain (IgG2a), ZINC ION, ...
Authors:Brooks, C.L., Evans, S.V., Borisova, S.N.
Deposit date:2009-07-23
Release date:2010-06-23
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Antibody recognition of a unique tumor-specific glycopeptide antigen.
Proc.Natl.Acad.Sci.USA, 107, 2010
2HF5
  • Download 2hf5
  • View 2hf5
Molmil generated image of 2hf5
THE STRUCTURE AND FUNCTION OF A NOVEL TWO-SITE CALCIUM-BINDING FRAGMENT OF CALMODULIN
Descriptor:Calmodulin, CALCIUM ION
Authors:Lakowski, T.M., Lee, G.M., Reid, R.E., McIntosh, L.P.
Deposit date:2006-06-23
Release date:2007-05-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3
Protein Sci., 16, 2007
2LF7
  • Download 2lf7
  • View 2lf7
Molmil generated image of 2lf7
INTRAMOLECULAR REGULATION OF THE ETS DOMAIN WITHIN ETV6 SEQUENCE R335 TO Q436
Descriptor:Transcription factor ETV6
Authors:Coyne III, H., Green, S.M., Graves, B.J., Mcintosh, L.P.
Deposit date:2011-06-28
Release date:2012-05-23
Last modified:2012-07-25
Method:SOLUTION NMR
Cite:Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
2LF8
  • Download 2lf8
  • View 2lf8
Molmil generated image of 2lf8
INTRAMOLECULAR REGULATION OF THE ETS DOMAIN WITHIN ETV6 SEQUENCE R335 TO R458
Descriptor:Transcription factor ETV6
Authors:Coyne III, H., Green, S.M., Graves, B.J., Mcintosh, L.P.
Deposit date:2011-06-28
Release date:2012-05-23
Last modified:2012-07-25
Method:SOLUTION NMR
Cite:Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
2MKY
  • Download 2mky
  • View 2mky
Molmil generated image of 2mky
STRUCTURE OF THE PRGK FIRST PERIPLASMIC DOMAIN
Descriptor:Pathogenicity 1 island effector protein
Authors:Bergeron, J., Mcintosh, L., Strynadka, N.
Deposit date:2014-02-14
Release date:2014-10-29
Last modified:2015-02-11
Method:SOLUTION NMR
Cite:The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body.
Structure, 23, 2015
<12>