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1VAS
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ATOMIC MODEL OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME COMPLEXED WITH A DNA SUBSTRATE: STRUCTURAL BASIS FOR DAMAGED DNA RECOGNITION
Descriptor:DNA (5'-D(*AP*TP*CP*GP*CP*GP*TP*TP*GP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*CP*AP*AP*CP*GP*CP*GP*A)-3'), PROTEIN (T4 ENDONUCLEASE V (E.C.3.1.25.1))
Authors:Vassylyev, D.G., Kashiwagi, T., Mikami, Y., Ariyoshi, M., Iwai, S., Ohtsuka, E., Morikawa, K.
Deposit date:1995-09-08
Release date:1996-01-31
Last modified:2013-05-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition.
Cell(Cambridge,Mass.), 83, 1995
1ENI
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CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS
Descriptor:ENDONUCLEASE V
Authors:Vassylyev, D.G., Ariyoshi, M., Matsumoto, O., Katayanagi, K., Ohtsuka, E., Morikawa, K.
Deposit date:1994-08-08
Release date:1994-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
1ENJ
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CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS
Descriptor:ENDONUCLEASE V
Authors:Vassylyev, D.G., Ariyoshi, M., Matsumoto, O., Katayanagi, K., Ohtsuka, E., Morikawa, K.
Deposit date:1994-08-08
Release date:1994-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
1ENK
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CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS
Descriptor:ENDONUCLEASE V
Authors:Vassylyev, D.G., Ariyoshi, M., Matsumoto, O., Katayanagi, K., Ohtsuka, E., Morikawa, K.
Deposit date:1994-08-08
Release date:1994-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
2END
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CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS
Descriptor:ENDONUCLEASE V
Authors:Vassylyev, D.G., Ariyoshi, M., Matsumoto, O., Katayanagi, K., Ohtsuka, E., Morikawa, K.
Deposit date:1994-08-08
Release date:1994-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
1EHL
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64M-2 ANTIBODY FAB COMPLEXED WITH D(5HT)(6-4)T
Descriptor:5'-(D(5HT)P*(6-4)T)-3', ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (LIGHT CHAIN), ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (HEAVY CHAIN)
Authors:Yokoyama, H., Mizutani, R., Satow, Y., Komatsu, Y., Ohtsuka, E., Nikaido, O.
Deposit date:2000-02-21
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation.
J.Mol.Biol., 299, 2000
1KEG
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ANTIBODY 64M-2 FAB COMPLEXED WITH DTT(6-4)TT
Descriptor:5'-D(*TP*(64T)P*TP*T)-3', Anti-(6-4) photoproduct antibody 64M-2 Fab (light chain), Anti-(6-4) photoproduct antibody 64M-2 Fab (heavy chain), ...
Authors:Yokoyama, H., Mizutani, R., Satow, Y., Sato, K., Komatsu, Y., Ohtsuka, E., Nikaido, O.
Deposit date:2001-11-15
Release date:2002-11-15
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the DNA (6-4) photoproduct dTT(6-4)TT in complex with the 64M-2 antibody Fab fragment implies increased antibody-binding affinity by the flanking nucleotides.
Acta Crystallogr.,Sect.D, 68, 2012
1DHH
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NMR SOLUTION STRUCTURE OF THE DNA DUPLEX CONTAINING DNA/RNA HYBRID REGION, D(GG)R(AGAU)D(GAC)/D(GTCATCTCC)
Descriptor:DNA/RNA (5'-D(*GP*G)-R(P*AP*GP*AP*U)-D(P*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*CP*TP*CP*C)-3')
Authors:Nishizaki, T., Iwai, S., Ohkubo, T., Kojima, C., Nakamura, H., Kyogoku, Y., Ohtsuka, E.
Deposit date:1995-10-18
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Strucutres of DNA duplexes containing a DNA x RNA hybrid region, d(GG)r(AGAU)d(GAC) x d(GTCATCTCC) and d(GGAGA)r(UGAC) x d(GTCATCTCC).
Biochemistry, 35, 1996
1DRN
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NMR SOLUTION STRUCTURE OF THE DNA DUPLEX CONTAINING DNA/RNA HYBRID REGION, D(GGAGA)R(UGAC)/D(GTCATCTCC)
Descriptor:DNA/RNA (5'-D(*GP*GP*AP*GP*A)-R(P*UP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*CP*TP*CP*C)-3')
Authors:Nishizaki, T., Iwai, S., Ohkubo, T., Kojima, C., Nakamura, H., Kyogoku, Y., Ohtsuka, E.
Deposit date:1995-11-15
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Strucutres of DNA duplexes containing a DNA x RNA hybrid region, d(GG)r(AGAU)d(GAC) x d(GTCATCTCC) and d(GGAGA)r(UGAC) x d(GTCATCTCC).
Biochemistry, 35, 1996
1NAO
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SOLUTION STRUCTURE OF AN RNA 2'-O-METHYLATED RNA DUPLEX CONTAINING AN RNA/DNA HYBRID SEGMENT AT THE CENTER, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:RNA (5'-R(*GP*GP*AP*GP*AP*UP*GP*AP*C)-3'), DNA/RNA (5'-R(*OMGP*OMUP*OMC)-D(P*AP*TP*CP*T)-R(P*OMCP*OMC)-3')
Authors:Nishizaki, T., Iwai, S., Ohtsuka, E., Nakamura, H.
Deposit date:1996-03-29
Release date:1997-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an RNA.2'-O-methylated RNA hybrid duplex containing an RNA.DNA hybrid segment at the center.
Biochemistry, 36, 1997
1UL1
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CRYSTAL STRUCTURE OF THE HUMAN FEN1-PCNA COMPLEX
Descriptor:Flap endonuclease-1, Proliferating cell nuclear antigen, MAGNESIUM ION
Authors:Sakurai, S., Kitano, K., Yamaguchi, H., Hamada, K., Okada, K., Fukuda, K., Uchida, M., Ohtsuka, E., Morioka, H., Hakoshima, T.
Deposit date:2003-09-05
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for recruitment of human flap endonuclease 1 to PCNA
EMBO J., 24, 2005
3VW3
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ANTIBODY 64M-5 FAB IN COMPLEX WITH A DOUBLE-STRANDED DNA (6-4) PHOTOPRODUCT
Descriptor:Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), DNA (5'-D(*GP*CP*GP*AP*GP*TP*GP*AP*(64T)P*(5PY)P*AP*TP*GP*GP*AP*CP*GP*G)-3'), ...
Authors:Yokoyama, H., Mizutani, R., Satow, Y.
Deposit date:2012-07-30
Release date:2013-03-27
Last modified:2014-04-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab
Acta Crystallogr.,Sect.D, 69, 2013
4Q21
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MOLECULAR SWITCH FOR SIGNAL TRANSDUCTION: STRUCTURAL DIFFERENCES BETWEEN ACTIVE AND INACTIVE FORMS OF PROTOONCOGENIC RAS PROTEINS
Descriptor:C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Kim, S.-H.
Deposit date:1991-09-25
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins.
Science, 247, 1990
6Q21
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MOLECULAR SWITCH FOR SIGNAL TRANSDUCTION: STRUCTURAL DIFFERENCES BETWEEN ACTIVE AND INACTIVE FORMS OF PROTOONCOGENIC RAS PROTEINS
Descriptor:C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Kim, S.-H.
Deposit date:1992-07-27
Release date:1992-07-28
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins.
Science, 247, 1990
1Q21
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CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
Descriptor:C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Kim, S.-H.
Deposit date:1991-09-25
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
J.Mol.Biol., 217, 1991
2Q21
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CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
Descriptor:C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Kim, S.-H.
Deposit date:1991-09-25
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
J.Mol.Biol., 217, 1991
6IDG
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ANTIBODY 64M-5 FAB IN COMPLEX WITH DT(6-4)T
Descriptor:Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), DNA (5'-D(*(64T)P*(5PY))-3')
Authors:Yokoyama, H., Mizutani, R., Noguchi, S., Hayashida, N.
Deposit date:2018-09-10
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the antibody 64M-5 Fab and its complex with dT(6-4)T indicate induced-fit and high-affinity mechanisms
Acta Crystallogr.,Sect.F, 75, 2019
6IDH
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ANTIBODY 64M-5 FAB IN LIGAND-FREE FORM
Descriptor:Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain)
Authors:Yokoyama, H., Mizutani, R., Noguchi, S., Hayashida, N.
Deposit date:2018-09-10
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the antibody 64M-5 Fab and its complex with dT(6-4)T indicate induced-fit and high-affinity mechanisms
Acta Crystallogr.,Sect.F, 75, 2019