Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5YFM
DownloadVisualize
BU of 5yfm by Molmil
Human isocitrate dehydrogenase 1 bound with NADP
Descriptor: Isocitrate dehydrogenase [NADP] cytoplasmic, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Nordlund, P, Chen, D, Jansson, A, Larsson, A.
Deposit date:2017-09-21
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human isocitrate dehydrogenase 1 bound with NADP
To Be Published
5YFN
DownloadVisualize
BU of 5yfn by Molmil
Human isocitrate dehydrogenase 1 bound with isocitrate
Descriptor: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, MAGNESIUM ION, ...
Authors:Nordlund, P, Chen, D, Jansson, A, Larsson, A.
Deposit date:2017-09-21
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human isocitrate dehydrogenase 1 bound with isocitrate
To Be Published
4LEP
DownloadVisualize
BU of 4lep by Molmil
Structural insights into substrate recognition in proton dependent oligopeptide transporters
Descriptor: N-[(1R)-1-phosphonoethyl]-L-alaninamide, Proton:oligopeptide symporter POT family, ZINC ION
Authors:Guettou, F, Quistgaard, E.M, Tresaugues, L, Moberg, P, Jegerschold, C, Zhu, L, Jong, A.J, Nordlund, P, Low, C.
Deposit date:2013-06-26
Release date:2013-07-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into substrate recognition in proton-dependent oligopeptide transporters.
Embo Rep., 14, 2013
2A98
DownloadVisualize
BU of 2a98 by Molmil
Crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate 3-kinase C
Authors:Hallberg, B.M, Ogg, D, Ehn, M, Graslund, S, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Persson, C, Sagemark, J, Schuler, H, Stenmark, P, Thorsell, A.-G, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Structural Genomics Consortium (SGC)
Deposit date:2005-07-11
Release date:2005-07-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C
To be Published
5WRN
DownloadVisualize
BU of 5wrn by Molmil
Human thymidylate synthase complexed with dCMP
Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Thymidylate synthase
Authors:Chen, D, Nordlund, P.
Deposit date:2016-12-02
Release date:2016-12-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Human thymidylate synthase complexed with dCMP
To Be Published
4CML
DownloadVisualize
BU of 4cml by Molmil
Crystal Structure of INPP5B in complex with Phosphatidylinositol 3,4- bisphosphate
Descriptor: 1,2-dioctanoyl phosphatidyl epi-inositol (3,4)-bisphosphate, CHLORIDE ION, GLYCEROL, ...
Authors:Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Ekblad, T, Flodin, S, Graslund, S, Karlberg, T, Moche, M, Nyman, T, Schuler, H, Silvander, C, Thorsell, A.G, Weigelt, J, Welin, M, Nordlund, P.
Deposit date:2014-01-16
Release date:2014-04-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases.
Structure, 22, 2014
4CMN
DownloadVisualize
BU of 4cmn by Molmil
Crystal structure of OCRL in complex with a phosphate ion
Descriptor: GLYCEROL, INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL-1, MAGNESIUM ION, ...
Authors:Tresaugues, L, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Ekblad, T, Flodin, S, Graslund, S, Karlberg, T, Nyman, T, Schuler, H, Silvander, C, Thorsell, A.G, Weigelt, J, Welin, M, Nordlund, P.
Deposit date:2014-01-16
Release date:2014-04-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases.
Structure, 22, 2014
4XAL
DownloadVisualize
BU of 4xal by Molmil
Crystal structure of the conserved core domain of VP22 from HSV-1
Descriptor: Tegument protein VP22, peptide SSGVDL
Authors:Hew, K, Dahlroth, S.L, Nordlund, P.
Deposit date:2014-12-15
Release date:2015-06-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.869 Å)
Cite:VP22 core domain from Herpes simplex virus 1 reveals a surprising structural conservation in both the Alpha- and Gammaherpesvirinae subfamilies.
J.Gen.Virol., 96, 2015
1H79
DownloadVisualize
BU of 1h79 by Molmil
STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DTTP
Descriptor: ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, FE (II) ION, MAGNESIUM ION, ...
Authors:Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T.
Deposit date:2001-07-04
Release date:2002-03-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
1H78
DownloadVisualize
BU of 1h78 by Molmil
STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DCTP.
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, MAGNESIUM ION
Authors:Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T.
Deposit date:2001-07-04
Release date:2002-07-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
1H7A
DownloadVisualize
BU of 1h7a by Molmil
Structural basis for allosteric substrate specificity regulation in class III ribonucleotide reductases: NRDD in complex with dATP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, FE (II) ION, ...
Authors:Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T.
Deposit date:2001-07-04
Release date:2002-03-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
5X5A
DownloadVisualize
BU of 5x5a by Molmil
Human thymidylate synthase bound with phosphate ion
Descriptor: PHOSPHATE ION, Thymidylate synthase
Authors:Chen, D, Jansson, A, Larsson, A, Nordlund, P.
Deposit date:2017-02-15
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
5X66
DownloadVisualize
BU of 5x66 by Molmil
Human thymidylate synthase in complex with dUMP and methotrexate
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, METHOTREXATE, Thymidylate synthase
Authors:Chen, D, Jansson, A, Larsson, A, Nordlund, P.
Deposit date:2017-02-21
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
2ACY
DownloadVisualize
BU of 2acy by Molmil
ACYL-PHOSPHATASE (COMMON TYPE) FROM BOVINE TESTIS
Descriptor: ACYLPHOSPHATASE, CHLORIDE ION, SULFATE ION
Authors:Thunnissen, M.M.G.M, Nordlund, P.
Deposit date:1996-11-08
Release date:1997-11-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of common type acylphosphatase from bovine testis.
Structure, 5, 1997
2XRF
DownloadVisualize
BU of 2xrf by Molmil
Crystal structure of human uridine phosphorylase 2
Descriptor: GLYCEROL, MAGNESIUM ION, URACIL, ...
Authors:Welin, M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P.
Deposit date:2010-09-14
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Uridine Phosphorylase 2
To be Published
2XRI
DownloadVisualize
BU of 2xri by Molmil
Crystal structure of human ERI1 exoribonuclease 3
Descriptor: ERI1 EXORIBONUCLEASE 3, GLYCEROL, MAGNESIUM ION
Authors:Welin, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P.
Deposit date:2010-09-15
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Human Eri1 Exoribonuclease 3
To be Published
1BIQ
DownloadVisualize
BU of 1biq by Molmil
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN MUTANT E238A
Descriptor: FE (II) ION, FE (III) ION, HYDROXIDE ION, ...
Authors:Logan, D.T, Demare, F, Persson, B.O, Slaby, A, Sjoberg, B.M, Nordlund, P.
Deposit date:1998-06-18
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants: structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins.
Biochemistry, 37, 1998
4DT4
DownloadVisualize
BU of 4dt4 by Molmil
Crystal structure of the PPIase-chaperone SlpA with the chaperone binding site occupied by the linker of the purification tag
Descriptor: FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase
Authors:Quistgaard, E.M, Nordlund, P, Loew, C.
Deposit date:2012-02-20
Release date:2012-07-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA.
Faseb J., 26, 2012
5HS3
DownloadVisualize
BU of 5hs3 by Molmil
Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol, Thymidylate synthase
Authors:Chen, D, Almqvist, H, Axelsson, H, Jafari, R, Mateus, A, Haraldsson, M, Larsson, A, Artursson, P, Molina, D.M, Lundback, T, Nordlund, P.
Deposit date:2016-01-25
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Nat Commun, 7, 2016
4TPH
DownloadVisualize
BU of 4tph by Molmil
Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2
Descriptor: 3,5 DIBROMOTYROSINE, ALANINE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P.
Deposit date:2014-06-07
Release date:2014-07-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.155 Å)
Cite:Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
Nat.Struct.Mol.Biol., 21, 2014
4TPG
DownloadVisualize
BU of 4tpg by Molmil
Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2
Descriptor: Ala-L-3-Br-Tyr-Ala, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ...
Authors:Guettou, F, Quistgaard, E.M, Raba, M, Moberg, P, Low, C, Nordlund, P.
Deposit date:2014-06-07
Release date:2014-07-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.91 Å)
Cite:Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
Nat.Struct.Mol.Biol., 21, 2014
4TPJ
DownloadVisualize
BU of 4tpj by Molmil
Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2
Descriptor: ALA-ALA-ALA, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ...
Authors:Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P.
Deposit date:2014-06-07
Release date:2014-07-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
Nat.Struct.Mol.Biol., 21, 2014
2XJF
DownloadVisualize
BU of 2xjf by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II with a covalently modified Asn52
Descriptor: (2R)-2,3-diphosphoglyceric acid, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL
Authors:Wallden, K, Nordlund, P.
Deposit date:2010-07-04
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
5IPX
DownloadVisualize
BU of 5ipx by Molmil
Structure of ORF49 from KSHV
Descriptor: ORF49 protein, SULFATE ION
Authors:Hew, K, Nordlund, P.
Deposit date:2016-03-10
Release date:2016-11-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Open Reading Frame 49 Protein Encoded by Kaposi's Sarcoma-Associated Herpesvirus.
J. Virol., 91, 2017
1H7B
DownloadVisualize
BU of 1h7b by Molmil
Structural basis for allosteric substrate specificity regulation in class III ribonucleotide reductases, native NRDD
Descriptor: ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, PHOSPHATE ION
Authors:Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T.
Deposit date:2001-07-04
Release date:2002-03-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon