Author results

4YCM
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CRYSTAL STRUCTURE OF THE CALCIUM PUMP WITH BOUND MARINE MACROLIDE BLS
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, SULFATE ION, ...
Authors:Morita, M., Ogawa, H., Ohno, O., Yamori, T., Suenaga, K., Toyoshima, C.
Deposit date:2015-02-20
Release date:2016-01-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
4YCN
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CRYSTAL STRUCTURE OF THE CALCIUM PUMP WITH BOUND MARINE MACROLIDE BLLB
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, SULFATE ION, ...
Authors:Morita, M., Ogawa, H., Ohno, O., Yamori, T., Suenaga, K., Toyoshima, C.
Deposit date:2015-02-20
Release date:2016-01-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
3DJN
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CRYSTAL STRUCTURE OF MOUSE TIS21
Descriptor:Protein BTG2
Authors:Yang, X., Morita, M., Wang, H., Suzuki, T., Bartlam, M., Yamamoto, T.
Deposit date:2008-06-24
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity
Nucleic Acids Res., 36, 2008
3DJU
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CRYSTAL STRUCTURE OF HUMAN BTG2
Descriptor:Protein BTG2
Authors:Yang, X., Morita, M., Wang, H., Suzuki, T., Bartlam, M., Yamamoto, T.
Deposit date:2008-06-24
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity
Nucleic Acids Res., 36, 2008
3NGN
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CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAIN IN COMPLEX WITH AMP
Descriptor:CCR4-NOT transcription complex subunit 6-like, ADENOSINE MONOPHOSPHATE
Authors:Wang, H., Morita, M., Yang, W., Bartlam, M., Yamamoto, T., Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGO
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CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAIN IN COMPLEX WITH POLY(A) DNA
Descriptor:CCR4-NOT transcription complex subunit 6-like, 5'-D(*AP*AP*AP*A)-3', MAGNESIUM ION
Authors:Wang, H., Morita, M., Yang, W., Bartlam, M., Yamamoto, T., Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGQ
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CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAIN
Descriptor:CCR4-NOT transcription complex subunit 6-like, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, MAGNESIUM ION
Authors:Wang, H., Morita, M., Yang, W., Bartlam, M., Yamamoto, T., Rao, Z.
Deposit date:2010-06-13
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3A5P
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CRYSTAL STRUCTURE OF HEMAGGLUTININ
Descriptor:Haemagglutinin I
Authors:Watanabe, N., Sakai, N., Nakamura, T., Nabeshima, Y., Kouno, T., Mizuguchi, M., Kawano, K.
Deposit date:2009-08-10
Release date:2010-08-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Structure of Physarum polycephalum hemagglutinin I suggests a minimal carbohydrate recognition domain of legume lectin fold
J.Mol.Biol., 405, 2011
5AON
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CRYSTAL STRUCTURE OF THE CONSERVED N-TERMINAL DOMAIN OF PEX14 FROM TRYPANOSOMA BRUCEI
Descriptor:PEROXIN 14, SULFATE ION
Authors:Obita, T., Sugawara, Y., Mizuguchi, M., Watanabe, Y., Kawaguchi, K., Imanaka, T.
Deposit date:2015-09-11
Release date:2015-12-23
Last modified:2016-02-10
Method:X-RAY DIFFRACTION (1.646 Å)
Cite:Characterization of the Interaction between Trypanosoma Brucei Pex5P and its Receptor Pex14P.
FEBS Lett., 590, 2016
6KDX
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CRYSTAL STRUCTURE OF PDE10A IN COMPLEX WITH A TRIAZOLOPYRIMIDINE INHIBITOR
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Amano, Y., Honbou, K.
Deposit date:2019-07-03
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors.
Bioorg.Med.Chem., 27, 2019
6KDZ
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CRYSTAL STRUCTURE OF PDE10A IN COMPLEX WITH A TRIAZOLOPYRIMIDINE INHIBITOR
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Amano, Y., Honbou, K.
Deposit date:2019-07-03
Release date:2019-08-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors.
Bioorg.Med.Chem., 27, 2019
6KE0
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CRYSTAL STRUCTURE OF PDE10A IN COMPLEX WITH A TRIAZOLOPYRIMIDINE INHIBITOR
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Amano, Y., Honbou, K.
Deposit date:2019-07-03
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors.
Bioorg.Med.Chem., 27, 2019
5TTY
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PAGF PRENYLTRANSFERASE
Descriptor:PagF prenyltransferase, DI(HYDROXYETHYL)ETHER
Authors:Hao, Y., Nair, S.K.
Deposit date:2016-11-04
Release date:2016-11-30
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis for the broad substrate selectivity of a peptide prenyltransferase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5TU4
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PAGF WITH BOC-TYR AND DMSPP
Descriptor:PagF prenyltransferase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, ...
Authors:Hao, Y., Nair, S.K.
Deposit date:2016-11-04
Release date:2016-11-30
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the broad substrate selectivity of a peptide prenyltransferase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5TU5
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PAGF PRENYLTRANSFERASE WITH TYR-TYR-TYR AND DMSPP
Descriptor:PagF prenyltransferase, TYR-TYR-TYR, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ...
Authors:Hao, Y., Nair, S.K.
Deposit date:2016-11-04
Release date:2016-11-30
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the broad substrate selectivity of a peptide prenyltransferase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5TU6
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PAGF PRENYLTRANSFERASE WITH CYCLIC[INPYLYP] AND DMSPP
Descriptor:PagF prenyltransferase, cyclic[INPYLYP] peptide, MAGNESIUM ION, ...
Authors:Hao, Y., Nair, S.K.
Deposit date:2016-11-04
Release date:2016-11-30
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Molecular basis for the broad substrate selectivity of a peptide prenyltransferase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6PGM
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PIRF GERANYLTRANSFERASE
Descriptor:PirF Geranyltransferase
Authors:Nair, S.K., Hao, Y., Estrada, P.
Deposit date:2019-06-24
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases.
J.Am.Chem.Soc., 140, 2018
6PGN
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PAGF SINGLE MUTANT WITH GPP
Descriptor:PagF, MAGNESIUM ION, GERANYL DIPHOSPHATE
Authors:Nair, S.K., Hao, Y., Estrada, P.
Deposit date:2019-06-24
Release date:2019-07-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases
J. Am. Chem. Soc., 140, 2018