Author results

4PBU
  • Download 4pbu
  • View 4pbu
Molmil generated image of 4pbu
SERIAL TIME-RESOLVED CRYSTALLOGRAPHY OF PHOTOSYSTEM II USING A FEMTOSECOND X-RAY LASER THE S1 STATE
Descriptor:Photosystem Q(B) protein 1, Photosystem II core light harvesting protein, Photosystem II CP43 protein, ...
Authors:Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K.N., Hunter, M., Shoeman, R.L., White, T.A., Wang, D., James, D., Yang, J.H., Cobb, D.E., Reeder, B., Sierra, R.G., Liu, H., Barty, A., Aquila, A., Deponte, D., Kirian, R.A., Bari, S., Bergkamp, J.J., Beyerlein, K., Bogan, M.J., Caleman, C., Chao, T.-C., Conrad, C.E., Davis, K.M., Fleckenstein, H., Galli, L., Hau-Riege, S.P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A.V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T.A., Moore, A.L., Pushkar, Y., Williams, G.J., Boutet, S., Doak, R.B., Weierstall, U., Frank, M., Chapman, H.N., Spence, J.C.H., Fromme, P.
Deposit date:2014-04-13
Release date:2014-07-16
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (5 Å)
Cite:Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Nature, 513, 2014
4RVY
  • Download 4rvy
  • View 4rvy
Molmil generated image of 4rvy
SERIAL TIME RESOLVED CRYSTALLOGRAPHY OF PHOTOSYSTEM II USING A FEMTOSECOND X-RAY LASER. THE S STATE AFTER TWO FLASHES (S3)
Descriptor:Photosystem II protein D1 1, Photosystem II CP47 reaction center protein, Photosystem II CP43 reaction center protein, ...
Authors:Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K.N., Hunter, M., Shoeman, R.L., White, T.A., Wang, D., James, D., Yang, J.-H., Cobb, D.E., Reeder, B., Sierra, R.G., Liu, H., Barty, A., Aquila, A., Deponte, D., Kirian, R., Bari, S., Bergkamp, J.J., Beyerlein, K., Bogan, M.J., Caleman, C., Chao, T.-C., Conrad, C.E., Davis, K.M., Fleckenstein, H., Galli, L., Hau-Riege, S.P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A.V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T.A., Moore, A.L., Pushkar, Y., Williams, G.J., Boutet, S., Doak, R.B., Weierstall, U., Frank, M., Chapman, H.N., Spence, J.C.H., Fromme, P.
Deposit date:2014-11-29
Release date:2015-11-04
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Nature, 513, 2014
3VV9
  • Download 3vv9
  • View 3vv9
Molmil generated image of 3vv9
CRYSTAL STRUCTURE OF CYANIDE-INSENSITIVE ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T., Kido, Y., Sakamoto, K., Inaoka, D.K., Tsuge, C., Tatsumi, R., Balogun, E.O., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Saimoto, H., Moore, A.L., Harada, S., Kita, K.
Deposit date:2012-07-17
Release date:2013-03-13
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
3VVA
  • Download 3vva
  • View 3vva
Molmil generated image of 3vva
CRYSTAL STRUCTURE OF CYANIDE-INSENSITIVE ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI WITH ASCOFURANONE DERIVATIVE
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T., Kido, Y., Sakamoto, K., Inaoka, D.K., Tsuge, C., Tatsumi, R., Balogun, E.O., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Saimoto, H., Moore, A.L., Harada, S., Kita, K.
Deposit date:2012-07-17
Release date:2013-03-13
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
3W54
  • Download 3w54
  • View 3w54
Molmil generated image of 3w54
CRYSTAL STRUCTURE OF CYANIDE-INSENSITIVE ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI WITH COLLETOCHLORIN B
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T., Kido, Y., Sakamoto, K., Inaoka, D.K., Tsuge, C., Tatsumi, R., Takahashi, G., Balogun, E.O., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Saimoto, H., Moore, A.L., Harada, S., Kita, K.
Deposit date:2013-01-21
Release date:2013-03-13
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
5GN5
  • Download 5gn5
  • View 5gn5
Molmil generated image of 5gn5
CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM TRYPANOSOMA BRUCEI GAMBIENSE COMPLEXED WITH CUMARIN DERIVATIVE-17
Descriptor:Glycerol kinase, 4-[[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-7,8-bis(oxidanyl)chromen-2-one, GLYCEROL
Authors:Balogun, E.O., Inaoka, D.K., Shiba, T., Tsuge, T., May, B., Sato, T., Kido, Y., Takeshi, N., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Watanabe, Y., Moore, A.L., Harada, S., Kita, K.
Deposit date:2016-07-19
Release date:2017-07-26
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Discovery of trypanocidal coumarins with dual-inhibition for African trypanosomes glycerol kinase and alternative oxidase
To Be Published
5GN6
  • Download 5gn6
  • View 5gn6
Molmil generated image of 5gn6
CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM TRYPANOSOMA BRUCEI GAMBIENSE COMPLEXED WITH CUMARIN DERIVATIVE-17B
Descriptor:Glycerol kinase, 4-butyl-7,8-bis(oxidanyl)chromen-2-one, GLYCEROL
Authors:Balogun, E.O., Inaoka, D.K., Shiba, T., Tsuge, T., May, B., Sato, T., Kido, Y., Takeshi, N., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Watanabe, Y., Moore, A.L., Harada, S., Kita, K.
Deposit date:2016-07-19
Release date:2017-07-26
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of trypanocidal coumarins with dual-inhibition for African trypanosomes glycerol kinase and alternative oxidase
To Be Published
5GN7
  • Download 5gn7
  • View 5gn7
Molmil generated image of 5gn7
CRYSTAL STRUCTURE OF ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI BRUCEI COMPLEXED WITH CUMARIN DERIVATIVE-17
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Balogun, E.O., Inaoka, D.K., Shiba, T., Tsuge, T., May, B., Sato, T., Kido, Y., Takeshi, N., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Watanabe, Y., Moore, A.L., Harada, S., Kita, K.
Deposit date:2016-07-19
Release date:2017-07-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Discovery of trypanocidal coumarins with dual-inhibition for African trypanosomes glycerol kinase and alternative oxidase
To Be Published
5GN9
  • Download 5gn9
  • View 5gn9
Molmil generated image of 5gn9
CRYSTAL STRUCTURE OF ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI BRUCEI COMPLEXED WITH CUMARIN DERIVATIVE-17B
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Balogun, E.O., Inaoka, D.K., Shiba, T., Tsuge, T., May, B., Sato, T., Kido, Y., Takeshi, N., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Watanabe, Y., Moore, A.L., Harada, S., Kita, K.
Deposit date:2016-07-19
Release date:2017-07-26
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Discovery of trypanocidal coumarins with dual-inhibition for African trypanosomes glycerol kinase and alternative oxidase
To Be Published
5ZDP
  • Download 5zdp
  • View 5zdp
Molmil generated image of 5zdp
CRYSTAL STRUCTURE OF CYANIDE-INSENSITIVE ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI WITH FERULENOL
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T., Inaoka, D.K., Takahashi, G., Tsuge, C., Kido, Y., Young, L., Ueda, S., Balogun, E.O., Nara, T., Honma, T., Tanaka, A., Inoue, M., Saimoto, H., Harada, S., Moore, A.L., Kita, K.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Biochim Biophys Acta Bioenerg, 1860, 2019
5ZDQ
  • Download 5zdq
  • View 5zdq
Molmil generated image of 5zdq
CRYSTAL STRUCTURE OF CYANIDE-INSENSITIVE ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI WITH COLLETOCHLORIN B
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T., Inaoka, D.K., Takahashi, G., Tsuge, C., Kido, Y., Young, L., Ueda, S., Balogun, E.O., Nara, T., Honma, T., Tanaka, A., Inoue, M., Saimoto, H., Harada, S., Moore, A.L., Kita, K.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Biochim Biophys Acta Bioenerg, 1860, 2019
5ZDR
  • Download 5zdr
  • View 5zdr
Molmil generated image of 5zdr
CRYSTAL STRUCTURE OF CYANIDE-INSENSITIVE ALTERNATIVE OXIDASE FROM TRYPANOSOMA BRUCEI WITH ASCOFURANONE DERIVATIVE
Descriptor:Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T., Inaoka, D.K., Takahashi, G., Tsuge, C., Kido, Y., Young, L., Ueda, S., Balogun, E.O., Nara, T., Honma, T., Tanaka, A., Inoue, M., Saimoto, H., Harada, S., Moore, A.L., Kita, K.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Biochim Biophys Acta Bioenerg, 1860, 2019
5ZF4
  • Download 5zf4
  • View 5zf4
Molmil generated image of 5zf4
STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH 275-10-COOME
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Miyazaki, Y., Inaoka, K.D., Shiba, T., Saimoto, H., Amalia, E., Kido, Y., Sakai, C., Nakamura, M., Moore, L.A., Harada, S., Kita, K.
Deposit date:2018-03-02
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
5ZF7
  • Download 5zf7
  • View 5zf7
Molmil generated image of 5zf7
STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH 277-9-OH
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Miyazaki, Y., Inaoka, K.D., Shiba, T., Saimoto, H., Amalia, E., Kido, Y., Sakai, C., Nakamura, M., Moore, L.A., Harada, S., Kita, K.
Deposit date:2018-03-02
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
5ZF8
  • Download 5zf8
  • View 5zf8
Molmil generated image of 5zf8
STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH 277-11-OAC
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Miyazaki, Y., Inaoka, K.D., Shiba, T., Saimoto, H., Amalia, E., Kido, Y., Sakai, C., Nakamura, M., Moore, L.A., Harada, S., Kita, K.
Deposit date:2018-03-02
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
5ZF9
  • Download 5zf9
  • View 5zf9
Molmil generated image of 5zf9
STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH 280-12
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Miyazaki, Y., Inaoka, K.D., Shiba, T., Saimoto, H., Amalia, E., Kido, Y., Sakai, C., Nakamura, M., Moore, L.A., Harada, S., Kita, K.
Deposit date:2018-03-02
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
5ZFA
  • Download 5zfa
  • View 5zfa
Molmil generated image of 5zfa
STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH 287-12-OCOIPR
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Miyazaki, Y., Inaoka, K.D., Shiba, T., Saimoto, H., Amalia, E., Kido, Y., Sakai, C., Nakamura, M., Moore, L.A., Harada, S., Kita, K.
Deposit date:2018-03-02
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
5ZFB
  • Download 5zfb
  • View 5zfb
Molmil generated image of 5zfb
STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH ASCOFURANONE (OPEN-FORM)
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Miyazaki, Y., Inaoka, K.D., Shiba, T., Saimoto, H., Amalia, E., Kido, Y., Sakai, C., Nakamura, M., Moore, L.A., Harada, S., Kita, K.
Deposit date:2018-03-02
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018