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1NAV
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THYROID RECEPTOR ALPHA IN COMPLEX WITH AN AGONIST SELECTIVE FOR THYROID RECEPTOR BETA1
Descriptor:hormone receptor alpha 1, THRA1, SULFATE ION, ...
Authors:Ye, L., Li, Y.L., Mellstrom, K., Mellin, C., Bladh, L.G., Koehler, K., Garg, N., Garcia Collazo, A.M., Litten, C., Husman, B., Persson, K., Ljunggren, J., Grover, G., Sleph, P.G., George, R., Malm, J.
Deposit date:2002-11-29
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
J.Med.Chem., 46, 2003
1NAX
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THYROID RECEPTOR BETA1 IN COMPLEX WITH A BETA-SELECTIVE LIGAND
Descriptor:Thyroid hormone receptor beta-1, {3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID
Authors:Ye, L., Li, Y.L., Mellstrom, K., Mellin, C., Bladh, L.G., Koehler, K., Garg, N., Garcia Collazo, A.M., Litten, C., Husman, B., Persson, K., Ljunggren, J., Grover, G., Sleph, P.G., George, R., Malm, J.
Deposit date:2002-11-29
Release date:2003-06-17
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
J.Med.Chem., 46, 2003
1R6G
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CRYSTAL STRUCTURE OF THE THYROID HORMONE RECEPTOR BETA LIGAND BINDING DOMAIN IN COMPLEX WITH A BETA SELECTIVE COMPOUND
Descriptor:Thyroid hormone receptor beta-1, 2-[3,5-DIBROMO-4-(4-HYDROXY-3-{HYDROXY[(2-PHENYLETHYL)AMINO]METHYL}PHENOXY)PHENYL]ETHANE-1,1-DIOL
Authors:Hangeland, J.J., Dejneka, T., Friends, T.J., Devasthale, P., Mellstrom, K., Sandberg, J., Grynfarb, M., Doweyko, A.M., Sack, J.S., Einspahr, H., Farnegardh, M., Husman, B., Ljunggren, J., Koehler, K., Sheppard, C., Malm, J., Ryono, D.E.
Deposit date:2003-10-15
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.
Bioorg.Med.Chem.Lett., 14, 2004