Author results

1NA6
  • Download 1na6
  • View 1na6
Molmil generated image of 1na6
CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE ECORII MUTANT R88A
Descriptor:Restriction endonuclease EcoRII
Authors:Zhou, X.E., Wang, Y., Reuter, M., Mucke, M., Kruger, D.H., Meehan, E.J., Chen, L.
Deposit date:2002-11-26
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding fold.
J.Mol.Biol., 335, 2004
1PN9
  • Download 1pn9
  • View 1pn9
Molmil generated image of 1pn9
CRYSTAL STRUCTURE OF AN INSECT DELTA-CLASS GLUTATHIONE S-TRANSFERASE FROM A DDT-RESISTANT STRAIN OF THE MALARIA VECTOR ANOPHELES GAMBIAE
Descriptor:Glutathione S-transferase 1-6, S-HEXYLGLUTATHIONE
Authors:Chen, L., Hall, P.R., Zhou, X.E., Ranson, H., Hemingway, J., Meehan, E.J.
Deposit date:2003-06-12
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae.
Acta Crystallogr.,Sect.D, 59, 2003
1QWK
  • Download 1qwk
  • View 1qwk
Molmil generated image of 1qwk
STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: HYPOTHETICAL 35.2 KDA PROTEIN (ALDOSE REDUCTASE FAMILY MEMBER)
Descriptor:aldo-keto reductase family 1 member C1
Authors:Chen, L., Zhou, X.E., Meehan, E.J., Symersky, J., Lu, S., Li, S., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-09-02
Release date:2003-09-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural genomics of Caenorhabditis Elegans: Hypothetical 35.2 kDa protein (aldose reductase family member)
To be published
1R7J
  • Download 1r7j
  • View 1r7j
Molmil generated image of 1r7j
CRYSTAL STRUCTURE OF THE DNA-BINDING PROTEIN SSO10A FROM SULFOLOBUS SOLFATARICUS
Descriptor:Conserved hypothetical protein Sso10a
Authors:Chen, L., Chen, L.R., Zhou, X.E., Wang, Y., Kahsai, M.A., Clark, A.T., Edmondson, S.P., Liu, Z.-J., Rose, J.P., Wang, B.C., Shriver, J.W., Meehan, E.J., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-10-21
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The hyperthermophile protein Sso10a is a dimer of winged helix DNA-binding domains linked by an antiparallel coiled coil rod.
J.Mol.Biol., 341, 2004
1RD6
  • Download 1rd6
  • View 1rd6
Molmil generated image of 1rd6
CRYSTAL STRUCTURE OF S. MARCESCENS CHITINASE A MUTANT W167A
Descriptor:Chitinase A
Authors:Aronson, N.N., Halloran, B.A., Alexyev, M.F., Zhou, X.E., Wang, Y., Meehan, E.J., Chen, L.
Deposit date:2003-11-05
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutation of a conserved tryptophan in the chitin-binding cleft of Serratia marcescens chitinase A enhances transglycosylation.
Biosci.Biotechnol.Biochem., 70, 2006
1S55
  • Download 1s55
  • View 1s55
Molmil generated image of 1s55
MOUSE RANKL STRUCTURE AT 1.9A RESOLUTION
Descriptor:Tumor necrosis factor ligand superfamily member 11, CHLORIDE ION
Authors:Teale, M.J., Feug, X., Chen, L., Bice, T., Meehan, E.J.
Deposit date:2004-01-19
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Murine RANKL Extra Cellular Domain Homotrimer Structure In Space Groups P212121 And H3 At 1.9 And 2.6 Respectively
To be Published
1WMS
  • Download 1wms
  • View 1wms
Molmil generated image of 1wms
HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN RAB9 GTPASE: A NOVEL ANTIVIRAL DRUG TARGET
Descriptor:Ras-related protein Rab-9A, GUANOSINE-5'-DIPHOSPHATE
Authors:Chen, L., DiGiammarino, E., Zhou, X.E., Wang, Y., Toh, D., Hodge, T.W., Meehan, E.J.
Deposit date:2004-07-16
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
1X6L
  • Download 1x6l
  • View 1x6l
Molmil generated image of 1x6l
CRYSTAL STRUCTURE OF S. MARCESCENS CHITINASE A MUTANT W167A
Descriptor:Chitinase A
Authors:Aronson Jr., N.N., Halloran, B.A., Alexyev, M.F., Zhou, X.E., Wang, Y., Meehan, E.J., Chen, L.
Deposit date:2004-08-11
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mutation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A caused enhanced transglycosylation
To be Published
1X6N
  • Download 1x6n
  • View 1x6n
Molmil generated image of 1x6n
CRYSTAL STRUCTURE OF S. MARCESCENS CHITINASE A MUTANT W167A IN COMPLEX WITH ALLOSAMIDIN
Descriptor:Chitinase A, ALLOSAMIDIN
Authors:Aronson Jr., N.N., Halloran, B.A., Alexyev, M.F., Zhou, X.E., Wang, Y., Meehan, E.J., Chen, L.
Deposit date:2004-08-11
Release date:2005-07-26
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Muation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A causes enhanced transglycosylation
To be Published
1ZLM
  • Download 1zlm
  • View 1zlm
Molmil generated image of 1zlm
CRYSTAL STRUCTURE OF THE SH3 DOMAIN OF HUMAN OSTEOCLAST STIMULATING FACTOR
Descriptor:Osteoclast stimulating factor 1
Authors:Chen, L., Wang, Y., Wells, D., Toh, D., Harold, H., Zhou, J., DiGiammarino, E., Meehan, E.J.
Deposit date:2005-05-06
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Structure of the SH3 domain of human osteoclast-stimulating factor at atomic resolution.
Acta Crystallogr.,Sect.F, 62, 2006
2IL3
  • Download 2il3
  • View 2il3
Molmil generated image of 2il3
STRUCTURES OF AN INSECT EPSILON-CLASS GLUTATHIONE S-TRANSFERASE FROM THE MALARIA VECTOR ANOPHELES GAMBIAE: EVIDENCE FOR HIGH DDT-DETOXIFYING ACTIVITY
Descriptor:Epsilon-class Glutathione S-transferase
Authors:Wang, Y., Hemingway, J., Ranson, H., Meehan, E.J., Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2IMI
  • Download 2imi
  • View 2imi
Molmil generated image of 2imi
STRUCTURES OF AN INSECT EPSILON-CLASS GLUTATHIONE S-TRANSFERASE FROM THE MALARIA VECTOR ANOPHELES GAMBIAE: EVIDENCE FOR HIGH DDT-DETOXIFYING ACTIVITY
Descriptor:Epsilon-class Glutathione S-transferase, GLUTATHIONE
Authors:Wang, Y., Hemingway, J., Ranson, H., Meehan, E.J., Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2IMK
  • Download 2imk
  • View 2imk
Molmil generated image of 2imk
STRUCTURES OF AN INSECT EPSILON-CLASS GLUTATHIONE S-TRANSFERASE FROM THE MALARIA VECTOR ANOPHELES GAMBIAE: EVIDENCE FOR HIGH DDT-DETOXIFYING ACTIVITY
Descriptor:Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE
Authors:Wang, Y., Hemingway, J., Ranson, H., Meehan, E.J., Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
3B9L
  • Download 3b9l
  • View 3b9l
Molmil generated image of 3b9l
HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTATE AND AZT
Descriptor:Serum albumin, MYRISTIC ACID, 3'-azido-3'-deoxythymidine
Authors:Zhu, L., Yang, F., Chen, L., Meehan, E.J., Huang, M.
Deposit date:2007-11-05
Release date:2008-05-27
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
3B9M
  • Download 3b9m
  • View 3b9m
Molmil generated image of 3b9m
HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTATE, 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT) AND SALICYLIC ACID
Descriptor:Serum albumin, MYRISTIC ACID, 3'-azido-3'-deoxythymidine, ...
Authors:Zhu, L., Yang, F., Chen, L., Meehan, E.J., Huang, M.
Deposit date:2007-11-05
Release date:2008-05-27
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
3E46
  • Download 3e46
  • View 3e46
Molmil generated image of 3e46
CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME E2-25KDA (HUNTINGTON INTERACTING PROTEIN 2) M172A MUTANT
Descriptor:Ubiquitin-conjugating enzyme E2-25 kDa, CALCIUM ION
Authors:Hughes, R.C., Wilson, R.C., Flatt, J.W., Meehan, E.J., Ng, J.D., Twigg, P.D.
Deposit date:2008-08-09
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2).
Acta Crystallogr.,Sect.F, 65, 2009
3F92
  • Download 3f92
  • View 3f92
Molmil generated image of 3f92
CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME E2-25KDA (HUNTINGTON INTERACTING PROTEIN 2) M172A MUTANT CRYSTALLIZED AT PH 8.5
Descriptor:Ubiquitin-conjugating enzyme E2 K, TETRAETHYLENE GLYCOL, BETA-MERCAPTOETHANOL, ...
Authors:Wilson, R.C., Hughes, R.C., Flatt, J.W., Meehan, E.J., Ng, J.D., Twigg, P.D.
Deposit date:2008-11-13
Release date:2008-11-25
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2).
Acta Crystallogr.,Sect.F, 65, 2009
3I98
  • Download 3i98
  • View 3i98
Molmil generated image of 3i98
X-RAY CRYSTALLOGRAPHIC STRUCTURE OF INORGANIC PYROPHOSPHATASE AT 298K FROM ARCHAEON THERMOCOCCUS THIOREDUCENS
Descriptor:Th-IPP, (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, ...
Authors:Hughes, R.C., Coates, L., Meehan, E.J., Ng, J.D.
Deposit date:2009-07-10
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray crystallographic structure of Inorganic Pyrophosphatase at 298K from archaeon Thermococcus thioreducens
To be Published
3KID
  • Download 3kid
  • View 3kid
Molmil generated image of 3kid
THE CRYSTAL STRUCTURES OF 2-AMINOBENZOTHIAZOLE-BASED INHIBITORS IN COMPLEXES WITH UROKINASE-TYPE PLASMINOGEN ACTIVATOR
Descriptor:Urokinase-type plasminogen activator, ethyl 2-amino-1,3-benzothiazole-6-carboxylate
Authors:Jiang, L.-G., Yu, H.Y., Yuan, C., Wang, J.D., Chen, L.Q., Meehan, E.J., Huang, Z.-X., Huang, M.-D.
Deposit date:2009-11-01
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
CHIN.J.STRUCT.CHEM., 28, 2009
3M61
  • Download 3m61
  • View 3m61
Molmil generated image of 3m61
CRYSTAL STRUCTURE OF COMPLEX OF UROKINASE AND A UPAIN-1 VARIANT(W3A) IN PH4.6 CONDITION
Descriptor:Urokinase-type plasminogen activator, upain-1 W3A
Authors:Jiang, L., Yuan, C., Wind, T., Andreasen, P.A., Chen, L., Meehan, E.J., Huang, M.
Deposit date:2010-03-15
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
TO BE PUBLISHED
3Q5V
  • Download 3q5v
  • View 3q5v
Molmil generated image of 3q5v
THE STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM THERMOCOCCUS THIOREDUCENS IN COMPLEX WITH MAGNESIUM AND SULFATE
Descriptor:Tt-IPPase, MAGNESIUM ION, SULFATE ION
Authors:Hughes, R.C., Coates, L., Meehan, E.J., Ng, J.D.
Deposit date:2010-12-29
Release date:2012-01-04
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:The structure of inorganic pyrophosphatase from Thermococcus Thioreducens in complex with magnesium and sulfate
To be Published
3R5U
  • Download 3r5u
  • View 3r5u
Molmil generated image of 3r5u
THE STRUCTURE OF MANGANESE BOUND THERMOCOCCUS THIOREDUCENS INORGANIC PYROPHOSPHATASE
Descriptor:Tt-IPPase, MANGANESE (II) ION
Authors:Hughes, R.C., Coates, L., Meehan, E.J., Garcia-Ruiz, J.M., Ng, J.D.
Deposit date:2011-03-19
Release date:2012-03-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The structure of manganese bound Thermococcus thioreducens Inorganic pyrophosphatase
To be Published
3R5V
  • Download 3r5v
  • View 3r5v
Molmil generated image of 3r5v
THE STRUCTURE OF CALCIUM BOUND THERMOCOCCUS THIOREDUCENS INORGANIC PYROPHOSPHATASE AT 298K
Descriptor:Tt-IPPase, CALCIUM ION, (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Hughes, R.C., Meehan, E.J., Coates, L., Ng, J.D.
Deposit date:2011-03-19
Release date:2012-03-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structure of calcium bound Thermococcus thioreducens inorganic pyrophosphatase at 298K
To be Published
3R6E
  • Download 3r6e
  • View 3r6e
Molmil generated image of 3r6e
THE STRUCTURE OF THERMOCOCCUS THIOREDUCENS' INORGANIC PYROPHOSPHATASE BOUND TO SULFATE
Descriptor:Tt-IPPase, SULFATE ION, AMMONIUM ION
Authors:Hughes, R.C., Meehan, E.J., Ng, J.D.
Deposit date:2011-03-21
Release date:2012-03-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:The structure of Thermococcus thioreducens' inorganic pyrophosphatase bound to sulfate
To be Published
5UCQ
  • Download 5ucq
  • View 5ucq
Molmil generated image of 5ucq
THE STRUCTURE OF ARCHAEAL INORGANIC PYROPHOSPHATASE IN COMPLEX WITH PYROPHOSPHATE
Descriptor:Inorganic pyrophosphatase, CALCIUM ION, 1,2-ETHANEDIOL, ...
Authors:Inoguchi, N., Hughes, R.C., Meehan, E.J., Ng, J.D.
Deposit date:2016-12-22
Release date:2017-02-08
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The structure of archaeal Inorganic Pyrophosphatase in complex with pyrophosphate
To Be Published
<12>