Author results

3JCF
  • Download 3jcf
  • View 3jcf
Molmil generated image of 3jcf
CRYO-EM STRUCTURE OF THE MAGNESIUM CHANNEL CORA IN THE CLOSED SYMMETRIC MAGNESIUM-BOUND STATE
Descriptor:Magnesium transport protein CorA, MAGNESIUM ION
Authors:Matthies, D., Perozo, E., Subramaniam, S.
Deposit date:2015-12-11
Release date:2016-02-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
3JCG
  • Download 3jcg
  • View 3jcg
Molmil generated image of 3jcg
CRYO-EM STRUCTURE OF THE MAGNESIUM CHANNEL CORA IN THE MAGNESIUM-FREE, ASYMMETRIC OPEN STATE I
Descriptor:Magnesium transport protein CorA
Authors:Matthies, D., Perozo, E., Subramaniam, S.
Deposit date:2015-12-11
Release date:2016-02-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.06 Å)
Cite:Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
3JCH
  • Download 3jch
  • View 3jch
Molmil generated image of 3jch
CRYO-EM STRUCTURE OF THE MAGNESIUM CHANNEL CORA IN THE MAGNESIUM-FREE, ASYMMETRIC OPEN STATE II
Descriptor:Magnesium transport protein CorA
Authors:Matthies, D., Perozo, E., Subramaniam, S.
Deposit date:2015-12-11
Release date:2016-02-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.06 Å)
Cite:Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
4BEM
  • Download 4bem
  • View 4bem
Molmil generated image of 4bem
CRYSTAL STRUCTURE OF THE F-TYPE ATP SYNTHASE C-RING FROM ACETOBACTERIUM WOODII.
Descriptor:F1FO ATPASE C2 SUBUNIT, F1FO ATPASE C1 SUBUNIT, SODIUM ION, ...
Authors:Matthies, D., Meier, T., Yildiz, O.
Deposit date:2013-03-11
Release date:2014-03-26
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-Resolution Structure and Mechanism of an F/V-Hybrid Rotor Ring in a Na+-Coupled ATP Synthase
Nat.Commun., 5, 2014
6EBK
  • Download 6ebk
  • View 6ebk
Molmil generated image of 6ebk
THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS
Descriptor:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBL
  • Download 6ebl
  • View 6ebl
Molmil generated image of 6ebl
THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS, CYTOSOLIC DOMAIN
Descriptor:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBM
  • Download 6ebm
  • View 6ebm
Molmil generated image of 6ebm
THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS, TRANSMEMBRANE DOMAIN OF SUBUNIT ALPHA
Descriptor:Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera
Authors:Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
3J7H
  • Download 3j7h
  • View 3j7h
Molmil generated image of 3j7h
STRUCTURE OF BETA-GALACTOSIDASE AT 3.2-A RESOLUTION OBTAINED BY CRYO-ELECTRON MICROSCOPY
Descriptor:Beta-galactosidase, MAGNESIUM ION
Authors:Bartesaghi, A., Matthies, D., Banerjee, S., Merk, A., Subramaniam, S.
Deposit date:2014-06-30
Release date:2014-07-30
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JCZ
  • Download 3jcz
  • View 3jcz
Molmil generated image of 3jcz
STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE IN THE UNLIGANDED STATE
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-27
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD0
  • Download 3jd0
  • View 3jd0
Molmil generated image of 3jd0
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH GTP
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD1
  • Download 3jd1
  • View 3jd1
Molmil generated image of 3jd1
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD2
  • Download 3jd2
  • View 3jd2
Molmil generated image of 3jd2
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD3
  • Download 3jd3
  • View 3jd3
Molmil generated image of 3jd3
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD4
  • Download 3jd4
  • View 3jd4
Molmil generated image of 3jd4
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
5A1A
  • Download 5a1a
  • View 5a1a
Molmil generated image of 5a1a
2.2 A RESOLUTION CRYO-EM STRUCTURE OF BETA-GALACTOSIDASE IN COMPLEX WITH A CELL-PERMEANT INHIBITOR
Descriptor:BETA-GALACTOSIDASE, 2-phenylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ...
Authors:Bartesaghi, A., Merk, A., Banerjee, S., Matthies, D., Wu, X., Milne, J., Subramaniam, S.
Deposit date:2015-04-29
Release date:2015-05-06
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor
Science, 348, 2015
3ZK1
  • Download 3zk1
  • View 3zk1
Molmil generated image of 3zk1
CRYSTAL STRUCTURE OF THE SODIUM BINDING ROTOR RING AT PH 5.3
Descriptor:ATP SYNTHASE SUBUNIT C, SODIUM ION, DECYL-BETA-D-MALTOPYRANOSIDE, ...
Authors:Schulz, S., Meier, T., Yildiz, O.
Deposit date:2013-01-21
Release date:2013-05-29
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A New Type of Na(+)-Driven ATP Synthase Membrane Rotor with a Two-Carboxylate Ion-Coupling Motif.
Plos Biol., 11, 2013
3ZK2
  • Download 3zk2
  • View 3zk2
Molmil generated image of 3zk2
CRYSTAL STRUCTURE OF THE SODIUM BINDING ROTOR RING AT PH 8.7
Descriptor:ATP SYNTHASE SUBUNIT C, SODIUM ION, DECYL-BETA-D-MALTOPYRANOSIDE
Authors:Schulz, S., Meier, T., Yildiz, O.
Deposit date:2013-01-21
Release date:2013-05-29
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:A new type of Na(+)-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif.
PLoS Biol., 11, 2013
4YE6
  • Download 4ye6
  • View 4ye6
Molmil generated image of 4ye6
THE CRYSTAL STRUCTURE OF THE INTACT HUMAN GLNRS
Descriptor:Glutamine--tRNA ligase
Authors:Ognjenovic, J., Wu, J., Ling, J., Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE8
  • Download 4ye8
  • View 4ye8
Molmil generated image of 4ye8
THE CRYSTAL STRUCTURE OF THE Y57H MUTANT OF HUMAN GLNRS
Descriptor:Glutamine--tRNA ligase
Authors:Ognjenovic, J., Wu, J., Ling, J., Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE9
  • Download 4ye9
  • View 4ye9
Molmil generated image of 4ye9
THE CRYSTAL STRUCTURE OF THE G45V MUTANT OF HUMAN GLNRS
Descriptor:Glutamine--tRNA ligase
Authors:Ognjenovic, J., Wu, J., Ling, J., Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4ZDL
  • Download 4zdl
  • View 4zdl
Molmil generated image of 4zdl
THE CRYSTAL STRUCTURE OF THE T325S MUTANT OF THE HUMAN HOLO SEPSECS
Descriptor:O-phosphoseryl-tRNA(Sec) selenium transferase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION
Authors:French, R.L., Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDO
  • Download 4zdo
  • View 4zdo
Molmil generated image of 4zdo
THE CRYSTAL STRUCTURE OF T325S MUTANT OF HUMAN SEPSECS IN COMPLEX WITH SELENOCYSTEINE TRNA (TRNASEC)
Descriptor:O-phosphoseryl-tRNA(Sec) selenium transferase, selenocysteine tRNA, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ...
Authors:French, R.L., Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDP
  • Download 4zdp
  • View 4zdp
Molmil generated image of 4zdp
THE CRYSTAL STRUCTURE OF Y334C MUTANT OF HUMAN SEPSECS IN COMPLEX WITH SELENOCYSTEINE TRNA (TRNASEC)
Descriptor:O-phosphoseryl-tRNA(Sec) selenium transferase, selenocysteine tRNA, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ...
Authors:French, R.L., Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016