Author results

1G5J
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COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD
分子名称:APOPTOSIS REGULATOR BCL-X, BAD PROTEIN
著者Petros, A.M., Nettesheim, D.G., Wang, Y., Olejniczak, E.T., Meadows, R.P., Mack, J., Swift, K., Matayoshi, E.D., Zhang, H., Thompson, C.B., Fesik, S.W.
登録日2000-11-01
公開日2001-02-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.
Protein Sci., 9, 2000
1G5M
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HUMAN BCL-2, ISOFORM 1
分子名称:PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN)
著者Petros, A.M., Medek, A., Nettesheim, D.G., Kim, D.H., Yoon, H.S., Swift, K., Matayoshi, E.D., Oltersdorf, T., Fesik, S.W.
登録日2000-11-01
公開日2001-03-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the antiapoptotic protein bcl-2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1GJH
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HUMAN BCL-2, ISOFORM 2
分子名称:PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN)
著者Petros, A.M., Medek, A., Nettesheim, D.G., Kim, D.H., Yoon, H.S., Swift, K., Matayoshi, E.D., Oltersdorf, T., Fesik, S.W.
登録日2001-05-31
公開日2001-06-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the antiapoptotic protein bcl-2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1M4M
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MOUSE SURVIVIN
分子名称:BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, ZINC ION
著者Muchmore, S.W., Chen, J., Jakob, C., Zakula, D., Matayoshi, E.D., Wu, W., Zhang, H., Li, F., Ng, S.C., Altieri, D.C.
登録日2002-07-03
公開日2002-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CRYSTAL STRUCTURE AND MUTAGENIC ANALYSIS OF THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN
MOL.CELL, 6, 2000
2E6W
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SOLUTION STRUCTURE AND CALCIUM BINDING PROPERTIES OF EF-HANDS 3 AND 4 OF CALSENILIN
分子名称:Calsenilin, CALCIUM ION
著者Yu, L., Sun, C., Mendoza, R., Hebert, E., Pereda-Lopez, A., Hajduk, P.J., Olejniczak, E.T.
登録日2007-01-05
公開日2007-11-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin.
Protein Sci., 16, 2007
2KP8
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LIGAND BOUND TO A MODEL PEPTIDE THAT MIMICS THE OPEN FUSOGENIC FORM
分子名称:Model peptide, 5-{[(4'-methoxybiphenyl-4-yl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid
著者Olejniczak, E.T.
登録日2009-10-09
公開日2010-01-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.
Bioorg.Med.Chem.Lett., 2009
2QF6
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HSP90 COMPLEXED WITH A56322
分子名称:Heat shock protein HSP 90-alpha, 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
著者Park, C.H.
登録日2007-06-26
公開日2008-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Chem.Biol.Drug Des., 70, 2007
2QFO
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HSP90 COMPLEXED WITH A143571 AND A516383
分子名称:Heat shock protein HSP 90-alpha, 4-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE, (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one
著者Park, C.H.
登録日2007-06-27
公開日2008-07-01
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
CHEM.BIOL.DRUG DES., 70, 2007
2QG0
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HSP90 COMPLEXED WITH A943037
分子名称:Heat shock protein HSP 90-alpha, N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE
著者Park, C.H.
登録日2007-06-28
公開日2008-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Chem.Biol.Drug Des., 70, 2007
2QG2
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HSP90 COMPLEXED WITH A917985
分子名称:Heat shock protein HSP 90-alpha, 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE
著者Park, C.H.
登録日2007-06-28
公開日2008-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Chem.Biol.Drug Des., 70, 2007