6DGV
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3OSR
| Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 311 | Descriptor: | Maltose-binding periplasmic protein,Green fluorescent protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Echevarria, I.M, Marvin, J.S, Looger, L.L, Schreiter, E.R. | Deposit date: | 2010-09-09 | Release date: | 2011-10-26 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A genetically encoded, high-signal-to-noise maltose sensor. Proteins, 79, 2011
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3OSQ
| Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 175 | Descriptor: | Maltose-binding periplasmic protein,Green fluorescent protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Echevarria, I.M, Marvin, J.S, Looger, L.L, Schreiter, E.R. | Deposit date: | 2010-09-09 | Release date: | 2011-10-26 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A genetically encoded, high-signal-to-noise maltose sensor. Proteins, 79, 2011
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6URU
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7S7U
| Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor with nicotine bound | Descriptor: | iNicSnFR 3.0 Fluorescent Nicotine Sensor | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
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7S7V
| Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor | Descriptor: | iNicSnFR 3.0 Fluorescent Nicotine Sensor | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
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7S7T
| iNicSnFR3a Nicotine Sensor comprising Periplasmic Binding sequence plus Fluorescent Sequence with varenicline bound | Descriptor: | IODIDE ION, VARENICLINE, iNicSnFR 3.0 Fluorescent Nicotine Sensor | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
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6PER
| Crystal Structure of Ligand-Free iSeroSnFR | Descriptor: | 1,2-ETHANEDIOL, iSeroSnFR, a soluble, ... | Authors: | Hartanto, S, Tian, L, Fisher, A.J. | Deposit date: | 2019-06-20 | Release date: | 2020-06-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning. Cell, 183, 2020
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6EFR
| Crystal Structure of iNicSnFR 1.0 | Descriptor: | iNicSnFR 1.0, a genetically encoded nicotine biosensor,Green fluorescent protein | Authors: | Shivange, A.V, Borden, P.M. | Deposit date: | 2018-08-17 | Release date: | 2019-01-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Nicotinic Drugs in the Endoplasmic Reticulum: Beginning the Inside-out Pathway of Addiction and Therapy J.Gen.Physiol., 2019
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3EK7
| Calcium-saturated GCaMP2 dimer | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | Deposit date: | 2008-09-18 | Release date: | 2008-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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3EK4
| Calcium-saturated GCaMP2 Monomer | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | Deposit date: | 2008-09-18 | Release date: | 2008-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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3EKH
| Calcium-saturated GCaMP2 T116V/K378W mutant monomer | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | Deposit date: | 2008-09-19 | Release date: | 2008-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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3EK8
| Calcium-saturated GCaMP2 T116V/G87R mutant monomer | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | Deposit date: | 2008-09-19 | Release date: | 2008-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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3EKJ
| Calcium-free GCaMP2 (calcium binding deficient mutant) | Descriptor: | Myosin light chain kinase, Green fluorescent protein, Calmodulin chimera | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | Deposit date: | 2008-09-19 | Release date: | 2008-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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4I2Y
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3P7I
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3QK6
| Crystal structure of Escherichia coli PhnD | Descriptor: | PhnD, subunit of alkylphosphonate ABC transporter, UNKNOWN LIGAND | Authors: | Alicea, I, Schreiter, E.R. | Deposit date: | 2011-01-31 | Release date: | 2011-10-12 | Last modified: | 2011-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the Escherichia coli Phosphonate Binding Protein PhnD and Rationally Optimized Phosphonate Biosensors. J.Mol.Biol., 414, 2011
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3QUJ
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3S4U
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3SG7
| Crystal Structure of GCaMP3-KF(linker 1) | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG5
| Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2) | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG3
| Crystal Structure of GCaMP3-D380Y | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG2
| Crystal Structure of GCaMP2-T116V,D381Y | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG6
| Crystal Structure of Dimeric GCaMP2-LIA(linker 1) | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG4
| Crystal Structure of GCaMP3-D380Y, LP(linker 2) | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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