Author results

2ASB
  • Download 2asb
  • View 2asb
Molmil generated image of 2asb
STRUCTURE OF A MYCOBACTERIUM TUBERCULOSIS NUSA-RNA COMPLEX
Descriptor:ribosomal RNA (5'- GAACUCAAUAG -3'), Transcription elongation protein nusA
Authors:Beuth, B., Pennell, S., Arnvig, K.B., Martin, S.R., Taylor, I.A.
Deposit date:2005-08-23
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
2BQZ
  • Download 2bqz
  • View 2bqz
Molmil generated image of 2bqz
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
Descriptor:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
Deposit date:2005-04-28
Release date:2005-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
1A54
  • Download 1a54
  • View 1a54
Molmil generated image of 1a54
PHOSPHATE-BINDING PROTEIN MUTANT A197C LABELLED WITH A COUMARIN FLUOROPHORE AND BOUND TO DIHYDROGENPHOSPHATE ION
Descriptor:PHOSPHATE-BINDING PROTEIN, DIHYDROGENPHOSPHATE ION, N-[2-(1-MALEIMIDYL)ETHYL]-7-DIETHYLAMINOCOUMARIN-3-CARBOXAMIDE
Authors:Hirshberg, M., Henrick, K., Lloyd-Haire, L., Vasisht, N., Brune, M., Corrie, J.E.T., Webb, M.R.
Deposit date:1998-02-19
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of phosphate binding protein labeled with a coumarin fluorophore, a probe for inorganic phosphate.
Biochemistry, 37, 1998
1MXE
  • Download 1mxe
  • View 1mxe
Molmil generated image of 1mxe
STRUCTURE OF THE COMPLEX OF CALMODULIN WITH THE TARGET SEQUENCE OF CAMKI
Descriptor:Calmodulin, Target Sequence of rat Calmodulin-Dependent Protein Kinase I, CALCIUM ION
Authors:Clapperton, J.A., Martin, S.R., Smerdon, S.J., Gamblin, S.J., Bayley, P.M.
Deposit date:2002-10-02
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the Complex of Calmodulin with the Target Sequence of Calmodulin-Dependent Protein Kinase I: Studies of the Kinase Activation Mechanism
Biochemistry, 41, 2002
2YP5
  • Download 2yp5
  • View 2yp5
Molmil generated image of 2yp5
HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP9
  • Download 2yp9
  • View 2yp9
Molmil generated image of 2yp9
HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP8
  • Download 2yp8
  • View 2yp8
Molmil generated image of 2yp8
HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3IIW
  • Download 3iiw
  • View 3iiw
Molmil generated image of 3iiw
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H3K27 PEPTIDE
Descriptor:Polycomb protein EED, Histone H3 peptide
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
2YP4
  • Download 2yp4
  • View 2yp4
Molmil generated image of 2yp4
HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP7
  • Download 2yp7
  • View 2yp7
Molmil generated image of 2yp7
HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP3
  • Download 2yp3
  • View 2yp3
Molmil generated image of 2yp3
HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP2
  • Download 2yp2
  • View 2yp2
Molmil generated image of 2yp2
HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CKZ
  • Download 3ckz
  • View 3ckz
Molmil generated image of 3ckz
N1 NEURAMINIDASE H274Y + ZANAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, ZANAMIVIR
Authors:Colllins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
4B7R
  • Download 4b7r
  • View 4b7r
Molmil generated image of 4b7r
H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, CALCIUM ION, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ...
Authors:Liu, J., van der Vries, E., Vachieri, S.G., Xiong, X., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4BH4
  • Download 4bh4
  • View 4bh4
Molmil generated image of 4bh4
HAEMAGGLUTININ FROM A TRANSMISSIBLE MUTANT H5 INFLUENZA VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3'-SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Xiong, X., Coombs, P.J., Martin, S.R., Liu, J., Xiao, H., McCauley, J.W., Locher, K., Walker, P.A., Collins, P.J., Kawaoka, Y., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-03-29
Release date:2013-04-24
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus
Nature, 497, 2013
4UO0
  • Download 4uo0
  • View 4uo0
Molmil generated image of 4uo0
STRUCTURE OF THE A_EQUINE_RICHMOND_07 H3 HAEMAGGLUTININ
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vachieri, S.G., Collins, P.J., Haire, L.F., Ogrodowicz, R.W., Martin, S.R., Walker, P.A., Xiong, X., Gamblin, S.J., Skehel, J.J.
Deposit date:2014-05-31
Release date:2014-07-23
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Recent Evolution of Equine Influenza and the Origin of Canine Influenza.
Proc.Natl.Acad.Sci.USA, 111, 2014
5JW5
  • Download 5jw5
  • View 5jw5
Molmil generated image of 5jw5
STRUCTURE OF MEDI8852 FAB FRAGMENT
Descriptor:MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION
Authors:Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
3IJC
  • Download 3ijc
  • View 3ijc
Molmil generated image of 3ijc
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH NDSB-195
Descriptor:Polycomb protein EED, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-04
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
4BH3
  • Download 4bh3
  • View 4bh3
Molmil generated image of 4bh3
HAEMAGGLUTININ FROM A TRANSMISSIBLE MUTANT H5 INFLUENZA VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6'-SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Xiong, X., Coombs, P.J., Martin, S.R., Liu, J., Xiao, H., McCauley, J.W., Locher, K., Walker, P.A., Collins, P.J., Kawaoka, Y., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-03-29
Release date:2013-04-24
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus
Nature, 497, 2013
6FLM
  • Download 6flm
  • View 6flm
Molmil generated image of 6flm
CRYSTAL STRUCTURE OF THE HUMAN TRIM25 PRYSPRY DOMAIN
Descriptor:E3 ubiquitin/ISG15 ligase TRIM25, SULFATE ION, CHLORIDE ION
Authors:Cusack, S., Kowalinski, E.
Deposit date:2018-01-26
Release date:2018-05-23
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
4CQY
  • Download 4cqy
  • View 4cqy
Molmil generated image of 4cqy
H5 (TYTY) DEL133/ILE155THR MUTANT HAEMAGGLUTININ IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE LSTA
Descriptor:HAEMAGGLUTININ HA1, HAEMAGGLUTININ HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xiong, X., Xiao, H., Martin, S.R., Coombs, P.J., Liu, J., Collins, P.J., Vachieri, S.G., Walker, P.A., Lin, Y.P., McCauley, J.W., Gamblin, S.J., Skehel, J.J.
Deposit date:2014-02-21
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enhanced Human Receptor Binding by H5 Haemagglutinins.
Virology, 456, 2014
1H3I
  • Download 1h3i
  • View 1h3i
Molmil generated image of 1h3i
CRYSTAL STRUCTURE OF THE HISTONE METHYLTRANSFERASE SET7/9
Descriptor:HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE, MAGNESIUM ION
Authors:Wilson, J.R., Jing, C., Walker, P.A., Martin, S.R., Howell, S.A., Blackburn, G.M., Gamblin, S.J., Xiao, B.
Deposit date:2002-09-04
Release date:2002-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
Cell(Cambridge,Mass.), 111, 2002
2V8Q
  • Download 2v8q
  • View 2v8q
Molmil generated image of 2v8q
CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-13
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
3IJ1
  • Download 3ij1
  • View 3ij1
Molmil generated image of 3ij1
CRYSTAL STRUCTURE OF EED IN COMPLEX WITH A TRIMETHYLATED HISTONE H4K20 PEPTIDE
Descriptor:Polycomb protein EED, Histone H4K20 peptide
Authors:Justin, N., Sharpe, M.L., Martin, S., Taylor, W.R., De Marco, V., Gamblin, S.J.
Deposit date:2009-08-03
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
4BSG
  • Download 4bsg
  • View 4bsg
Molmil generated image of 4bsg
CRYSTAL STRUCTURE OF AN H7N3 AVIAN INFLUENZA VIRUS HAEMAGGLUTININ
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013