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2LQH
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BU of 2lqh by Molmil
NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation)
Descriptor: CREB-binding protein, Forkhead box O3
Authors:Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M.
Deposit date:2012-03-06
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
2LQI
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BU of 2lqi by Molmil
NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation)
Descriptor: CREB-binding protein, Forkhead box O3
Authors:Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M.
Deposit date:2012-03-06
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
6I1S
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BU of 6i1s by Molmil
Crystal structure of the ACVR1 (ALK2) kinase in complex with FKBP12 and the inhibitor E6201
Descriptor: (4~{S},5~{R},6~{Z},9~{S},10~{S},12~{E})-16-(ethylamino)-4,5-dimethyl-9,10,18-tris(oxidanyl)-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione, 1,2-ETHANEDIOL, Activin receptor type-1, ...
Authors:Williams, E.P, Pinkas, D.M, Fortin, J, Newman, J.A, Bradshaw, W.J, Mahajan, P, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2018-10-30
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Cancer Cell, 37, 2020
2K86
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BU of 2k86 by Molmil
Solution Structure of FOXO3a Forkhead domain
Descriptor: Forkhead box protein O3
Authors:Wang, F, Marshall, C.B, Li, G, Plevin, M.J, Ikura, M.
Deposit date:2008-09-02
Release date:2008-10-14
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53.
J.Mol.Biol., 384, 2008
4CAY
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BU of 4cay by Molmil
Crystal structure of a human Anp32e-H2A.Z-H2B complex
Descriptor: ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E, HISTONE H2A.Z, HISTONE H2B TYPE 1-J
Authors:Obri, A, Ouararhni, K, Papin, C, Diebold, M.-L, Padmanabhan, K, Marek, M, Stoll, I, Roy, L, Reilly, P.T, Mak, T.W, Dimitrov, S, Romier, C, Hamiche, A.
Deposit date:2013-10-09
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Anp32E is a Histone Chaperone that Removes H2A.Z from Chromatin
Nature, 648, 2014

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