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4V2V
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JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H3K27ME3 PEPTIDE (25-29) ARK(ME3)SA
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4A, HISTONE H3.1T, N-OXALYLGLYCINE, ...
Authors:Chowdhury, R., Madden, S.K., Schofield, C.J.
Deposit date:2014-10-15
Release date:2014-11-05
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies on the Catalytic Domains of Multiple Jmjc Oxygenases Using Peptide Substrates.
Epigenetics, 9, 2014
5LY2
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JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND MACROCYCLIC PEPTIDE INHIBITOR CP2_R6KME3 (13-MER)
Descriptor:Lysine-specific demethylase 4A, CP2_R6Kme3, NICKEL (II) ION, ...
Authors:CHOWDHURY, R., Madden, S.K., Hopkinson, R., SCHOFIELD, C.J.
Deposit date:2016-09-23
Release date:2017-04-12
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Nat Commun, 8, 2017
3ZLI
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CRYSTAL STRUCTURE OF JMJC DOMAIN OF HUMAN HISTONE DEMETHYLASE UTY
Descriptor:HISTONE DEMETHYLASE UTY, 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, ...
Authors:Vollmar, M., Gileadi, C., Shrestha, L., Goubin, S., Johansson, C., Krojer, T., Raynor, J.W., Bradley, A., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
Deposit date:2013-01-31
Release date:2013-02-27
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human Uty(Kdm6C) is a Male-Specific Nepsilon-Methyl Lysyl Demethylase.
J.Biol.Chem., 289, 2014
3ZPO
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CRYSTAL STRUCTURE OF JMJC DOMAIN OF HUMAN HISTONE DEMETHYLASE UTY WITH BOUND GSK J1
Descriptor:HISTONE DEMETHYLASE UTY, 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, ZINC ION, ...
Authors:Vollmar, M., Gileadi, C., Shrestha, L., Goubin, S., Johansson, C., Krojer, T., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human Uty(Kdm6C) is a Male-Specific Nepislon-Methyl Lysyl Demethylase.
J.Biol.Chem., 289, 2014
4V2W
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JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H3K27ME3 PEPTIDE (16-35)
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4A, HISTONE H3.1T, NICKEL (II) ION, ...
Authors:Chowdhury, R., Zafred, D., Schofield, C.J.
Deposit date:2014-10-15
Release date:2014-11-26
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Studies on the Catalytic Domains of Multiple Jmjc Oxygenases Using Peptide Substrates.
Epigenetics, 9, 2014