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5DRB
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CRYSTAL STRUCTURE OF WNK1 IN COMPLEX WITH WNK463
分子名称:Serine/threonine-protein kinase WNK1, N-tert-butyl-1-(1-{5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-yl}piperidin-4-yl)-1H-imidazole-5-carboxamide
著者Kohls, D., Xie, X.
登録日2015-09-15
公開日2016-09-07
最終更新日2016-11-02
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Small-molecule WNK inhibition regulates cardiovascular and renal function.
Nat.Chem.Biol., 12, 2016
4JBJ
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STRUCTURAL MIMICRY FOR FUNCTIONAL ANTAGONISM
分子名称:Interferon-activable protein 202
著者Ru, H., Ni, X., Ma, F., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4QGU
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PROTEIN DOMAIN COMPLEX WITH SSDNA
分子名称:Gamma-interferon-inducible protein 16, DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3')
著者Ni, X., Ru, H., Zhao, L., Shaw, N., Ding, W., Songying, O., Liu, Z.-J.
登録日2014-05-25
公開日2015-06-17
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
J Mol Cell Biol, 8, 2016
5Z12
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A STRUCTURE OF FXR/RXR
分子名称:Bile acid receptor, Retinoic acid receptor RXR-alpha, Peptide from Nuclear receptor coactivator 2, ...
著者Lu, Y., Li, Y.
登録日2017-12-23
公開日2018-07-04
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural insights into the heterodimeric complex of the nuclear receptors FXR and RXR
J. Biol. Chem., 293, 2018