6E1L
| GRN3Ala | Descriptor: | Granulin | Authors: | Dastpeyman, M, Bansal, P, Wilson, D, Sotillo, J, Brindley, P, Loukas, A, Smout, M, Daly, N. | Deposit date: | 2018-07-10 | Release date: | 2019-02-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Variants of a Liver Fluke Derived Granulin Peptide Potently Stimulate Wound Healing. J. Med. Chem., 61, 2018
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6NUG
| hGRNA4-28_3s | Descriptor: | Granulin-4 | Authors: | Dastpeyman, M, Bansal, P, Wilson, D, Loukas, A, Smout, M, Daly, N. | Deposit date: | 2019-02-01 | Release date: | 2020-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | hGRN4-28_3s to be published
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1U53
| Novel X-Ray Structure of Na-ASP-2, a PR-1 protein from the nematode parasite Necator americanus and a vaccine antigen for human hookworm infection | Descriptor: | secreted protein ASP-2 | Authors: | Asojo, O.A, Goud, G, Dhar, K, Loukas, A, Zhan, B, Deumic, V, Liu, S, Borgstahl, G.E.O, Hotez, P.J. | Deposit date: | 2004-07-26 | Release date: | 2005-02-01 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J.Mol.Biol., 346, 2005
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3S63
| Saposin-like protein Na-SLP-1 | Descriptor: | Saposin-like protein | Authors: | Willis, C, Wang, C.K, Osman, A, Simon, A, Mulvenna, J, Pickering, D, Riboldi-Tunicliffe, A, Jones, M.K, Loukas, A, Hofmann, A. | Deposit date: | 2011-05-24 | Release date: | 2012-01-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm. Plos One, 6, 2011
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3S64
| Saposin-like protein Ac-SLP-1 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, Saposin-like protein 1 | Authors: | Willis, C, Wang, C.K, Osman, A, Simon, A, Mulvenna, J, Pickering, D, Riboldi-Tunicliffe, A, Jones, M.K, Loukas, A, Hofmann, A. | Deposit date: | 2011-05-25 | Release date: | 2012-01-18 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm. Plos One, 6, 2011
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3S6U
| Caclcium-bound Ac-ASP-7 | Descriptor: | Ac-ASP-7, CALCIUM ION | Authors: | Osman, A, Wang, C.K, Winter, A, Loukas, A, Tribolet, L, Gasser, R, Hofmann, A. | Deposit date: | 2011-05-26 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions. Biotechnol Adv, 30
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3S6S
| Ancylostoma-secreted protein Ac-ASP-7 | Descriptor: | Ac-ASP-7 | Authors: | Osman, A, Wang, C.K, Winter, A, Loukas, A, Tribolet, L, Gasser, R, Hofmann, A. | Deposit date: | 2011-05-26 | Release date: | 2012-04-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions. Biotechnol Adv, 30
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3S6V
| Manganese-bound Ac-ASP-7 | Descriptor: | Ac-ASP-7, MANGANESE (II) ION | Authors: | Osman, A, Wang, C.K, Winter, A, Loukas, A, Tribolet, L, Gasser, R, Hofmann, A. | Deposit date: | 2011-05-26 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions. Biotechnol Adv, 30
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5UJH
| ov-GRN12-34 | Descriptor: | Granulin | Authors: | Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N. | Deposit date: | 2017-01-18 | Release date: | 2018-01-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold. J. Med. Chem., 60, 2017
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5UJG
| ovGRN12-35_3s | Descriptor: | Granulin | Authors: | Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N. | Deposit date: | 2017-01-17 | Release date: | 2018-01-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold. J. Med. Chem., 60, 2017
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8UXR
| TxVIIB,U-superfamily conotoxin | Descriptor: | Conotoxin Tx6.5 | Authors: | Raffaelli, T, Daly, N. | Deposit date: | 2023-11-09 | Release date: | 2024-03-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural analysis of a U-superfamily conotoxin containing a mini-granulin fold: Insights into key features that distinguish between the ICK and granulin folds. J.Biol.Chem., 300, 2024
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2M7Z
| Structure of SmTSP2EC2 | Descriptor: | CD63-like protein Sm-TSP-2 | Authors: | Mulvenna, J, Jia, X. | Deposit date: | 2013-05-02 | Release date: | 2014-01-22 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure, membrane interactions, and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni J.Biol.Chem., 289, 2014
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8FA3
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7T6G
| Truncated Ac-AIP-2 | Descriptor: | Truncated Ac-AIP-2 | Authors: | Daly, N.L, Cobos, C. | Deposit date: | 2021-12-13 | Release date: | 2022-10-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells. Front Med (Lausanne), 9, 2022
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6PPC
| Solution structure of conotoxin MiXXVIIA | Descriptor: | Conopeptide phi-MiXXVIIA | Authors: | Daly, N.L, Dekan, Z, Jin, A.H, Alewood, P.F. | Deposit date: | 2019-07-06 | Release date: | 2019-08-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conotoxin phi-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity. Angew. Chem. Int. Ed. Engl., 56, 2017
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7L2G
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7K1M
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4NUK
| Crystal structure of nickel-bound Na-ASP-2 | Descriptor: | Ancylostoma secreted protein 2, NICKEL (II) ION | Authors: | Hofmann, A. | Deposit date: | 2013-12-03 | Release date: | 2014-05-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2. Int.J.Biochem.Cell Biol., 50, 2014
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4NUN
| Crystal structure of copper-bound Na-ASP-2 | Descriptor: | Ancylostoma secreted protein 2, COPPER (II) ION | Authors: | Hofmann, A. | Deposit date: | 2013-12-03 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2. Int.J.Biochem.Cell Biol., 50, 2014
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4NUO
| Crystal structure of zinc-bound Na-ASP-2 | Descriptor: | Ancylostoma secreted protein 2, ZINC ION | Authors: | Hofmann, A. | Deposit date: | 2013-12-03 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2. Int.J.Biochem.Cell Biol., 50, 2014
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4NUI
| Crystal structure of cobalt-bound Na-ASP-2 | Descriptor: | Ancylostoma secreted protein 2, COBALT (II) ION | Authors: | Hofmann, A. | Deposit date: | 2013-12-03 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2. Int.J.Biochem.Cell Biol., 50, 2014
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7JIA
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7JIY
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5VFW
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5VAV
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