Author results

1INN
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CRYSTAL STRUCTURE OF D. RADIODURANS LUXS, P21
Descriptor:AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION, METHIONINE
Authors:Lewis, H.A., Furlong, E.B., Bergseid, M.G., Sanderson, W.E., Buchanan, S.G.
Deposit date:2001-05-14
Release date:2001-06-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs.
Structure, 9, 2001
1J6V
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CRYSTAL STRUCTURE OF D. RADIODURANS LUXS, C2
Descriptor:AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION
Authors:Lewis, H.A., Furlong, E.B., Bergseid, M.G., Sanderson, W.E., Buchanan, S.G.
Deposit date:2001-05-14
Release date:2001-06-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs.
Structure, 9, 2001
1J6W
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CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE LUXS
Descriptor:AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION, METHIONINE
Authors:Lewis, H.A., Furlong, E.B., Bergseid, M.G., Sanderson, W.E., Buchanan, S.G.
Deposit date:2001-05-14
Release date:2001-06-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs.
Structure, 9, 2001
1J6X
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CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS
Descriptor:AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION, METHIONINE
Authors:Lewis, H.A., Furlong, E.B., Bergseid, M.G., Sanderson, W.E., Buchanan, S.G.
Deposit date:2001-05-14
Release date:2001-06-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs.
Structure, 9, 2001
1DT4
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CRYSTAL STRUCTURE OF NOVA-1 KH3 K-HOMOLOGY RNA-BINDING DOMAIN
Descriptor:NEURO-ONCOLOGICAL VENTRAL ANTIGEN 1
Authors:Lewis, H.A., Chen, H., Edo, C., Buckanovich, R.J., Yang, Y.Y.L.
Deposit date:2000-01-11
Release date:2000-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.
Structure Fold.Des., 7, 1999
1DTJ
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CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN
Descriptor:RNA-BINDING NEUROONCOLOGICAL VENTRAL ANTIGEN 2
Authors:Lewis, H.A., Chen, H., Edo, C., Buckanovich, R.J., Yang, Y.Y.L., Musunuru, K., Zhong, R., Darnell, R.B., Burley, S.K.
Deposit date:2000-01-12
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.
Structure Fold.Des., 7, 1999
1EC6
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CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN
Descriptor:20-MER RNA HAIRPIN, RNA-BINDING PROTEIN NOVA-2
Authors:Lewis, H.A., Musunuru, K., Jensen, K.B., Edo, C., Chen, H.
Deposit date:2000-01-25
Release date:2000-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
Cell(Cambridge,Mass.), 100, 2000
1Q3H
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MOUSE CFTR NBD1 WITH AMP.PNP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Lewis, H.A., Buchanan, S.G., Burley, S.K., Conners, K., Dickey, M., Dorwart, M., Fowler, R., Gao, X., Guggino, W.B., Hendrickson, W.A.
Deposit date:2003-07-29
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Embo J., 23, 2004
1R0W
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) NUCLEOTIDE-BINDING DOMAIN ONE (NBD1) APO
Descriptor:Cystic fibrosis transmembrane conductance regulator, ACETIC ACID
Authors:Lewis, H.A., Buchanan, S.G., Burley, S.K., Conners, K., Dickey, M., Dorwart, M., Fowler, R., Gao, X., Guggino, W.B., Hendrickson, W.A.
Deposit date:2003-09-23
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Embo J., 23, 2004
1R0X
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) NUCLEOTIDE-BINDING DOMAIN ONE (NBD1) WITH ATP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Lewis, H.A., Buchanan, S.G., Burley, S.K., Conners, K., Dickey, M., Dorwart, M., Fowler, R., Gao, X., Guggino, W.B., Hendrickson, W.A.
Deposit date:2003-09-23
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Embo J., 23, 2004
1R0Y
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) NUCLEOTIDE-BINDING DOMAIN ONE (NBD1) WITH ADP
Descriptor:Cystic fibrosis transmembrane conductance regulator, ADENOSINE-5'-DIPHOSPHATE, ACETIC ACID
Authors:Lewis, H.A., Buchanan, S.G., Burley, S.K., Conners, K., Dickey, M., Dorwart, M., Fowler, R., Gao, X., Guggino, W.B., Hendrickson, W.A.
Deposit date:2003-09-23
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Embo J., 23, 2004
1R0Z
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PHOSPHORYLATED CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) NUCLEOTIDE-BINDING DOMAIN ONE (NBD1) WITH ATP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Lewis, H.A., Buchanan, S.G., Burley, S.K., Conners, K., Dickey, M., Dorwart, M., Fowler, R., Gao, X., Guggino, W.B., Hendrickson, W.A.
Deposit date:2003-09-23
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Embo J., 23, 2004
1R10
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) NUCLEOTIDE-BINDING DOMAIN ONE (NBD1) WITH ATP, I4122 SPACE GROUP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Lewis, H.A., Buchanan, S.G., Burley, S.K., Conners, K., Dickey, M., Dorwart, M., Fowler, R., Gao, X., Guggino, W.B., Hendrickson, W.A.
Deposit date:2003-09-23
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Embo J., 23, 2004
1XMI
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CRYSTAL STRUCTURE OF HUMAN F508A NBD1 DOMAIN WITH ATP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Zhao, X., Wang, C., Sauder, J.M., Rooney, I., Noland, B.W., Lorimer, D., Kearins, M.C., Conners, K., Condon, B., Maloney, P.C., Guggino, W.B., Hunt, J.F., Emtage, S., Structural GenomiX
Deposit date:2004-10-02
Release date:2004-11-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J.Biol.Chem., 280, 2005
1XMJ
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CRYSTAL STRUCTURE OF HUMAN DELTAF508 HUMAN NBD1 DOMAIN WITH ATP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Zhao, X., Wang, C., Sauder, J.M., Rooney, I., Noland, B.W., Lorimer, D., Kearins, M.C., Conners, K., Condon, B., Maloney, P.C., Guggino, W.B., Hunt, J.F., Emtage, S., Structural GenomiX
Deposit date:2004-10-02
Release date:2004-11-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J.Biol.Chem., 280, 2005
2BBO
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HUMAN NBD1 WITH PHE508
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Kearins, M.C., Conners, K., Zhao, X., Lu, F., Sauder, J.M., Emtage, S.
Deposit date:2005-10-17
Release date:2005-11-01
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
2BBS
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HUMAN DELTAF508 NBD1 WITH THREE SOLUBILIZING MUTATIONS
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Kearins, M.C., Conners, K., Zhao, X., Lu, F., Sauder, J.M., Emtage, S.
Deposit date:2005-10-17
Release date:2005-11-01
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
2BBT
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HUMAN DELTAF508 NBD1 WITH TWO SOLUBLIZING MUTATIONS.
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Kearins, M.C., Conners, K., Zhao, X., Lu, F., Sauder, J.M., Emtage, S.
Deposit date:2005-10-17
Release date:2005-11-01
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
4DYA
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-885986 LIGAND BOUND
Descriptor:Nucleocapsid protein, N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]furan-2-carboxamide
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-28
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:To be determined
To be Published
4DYB
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-883559 LIGAND BOUND
Descriptor:Nucleocapsid protein, N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]thiophene-2-carboxamide
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-28
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:To be determined
To be Published
4DYN
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-885838 LIGAND BOUND
Descriptor:Nucleocapsid protein, N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]pyridine-2-carboxamide
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:To be determined
To be Published
4DYP
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-831780 LIGAND BOUND
Descriptor:Nucleocapsid protein, [4-(5-bromanyl-3-methyl-pyridin-2-yl)piperazin-1-yl]-[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:To be determined
To be Published
4DYS
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CRYSTAL STRUCTURE OF APO SWINE FLU INFLUENZA NUCLEOPROTEIN
Descriptor:Nucleocapsid protein
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:To be determined
To be Published
4DYT
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH THREE MUTATIONS (E53D, Y289H, Y313V)
Descriptor:Nucleocapsid protein
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:To be determined
To be Published
3DK3
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CRYSTAL STRUCTURE OF MUTANT ABL KINASE DOMAIN IN COMPLEX WITH SMALL MOLECULE FRAGMENT
Descriptor:Proto-oncogene tyrosine-protein kinase ABL1, 2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide, SULFATE ION
Authors:Lewis, H.A.
Deposit date:2008-06-24
Release date:2008-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of mutant ABL kinase domain in complex with small molecule fragment
To be Published