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8PRK
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THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS
Descriptor:PROTEIN (INORGANIC PYROPHOSPHATASE), MANGANESE (II) ION, PHOSPHATE ION
Authors:Tuominen, V., Heikinheimo, P., Kajander, T., Torkkel, T., Hyytia, T., Kapyla, J., Lahti, R., Cooperman, B.S., Goldman, A.
Deposit date:1998-09-16
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
J.Mol.Biol., 284, 1998
117E
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THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS
Descriptor:PROTEIN (INORGANIC PYROPHOSPHATASE), MANGANESE (II) ION, PHOSPHATE ION
Authors:Tuominen, V., Heikinheimo, P., Kajander, T., Torkkel, T., Hyytia, T., Kapyla, J., Lahti, R., Cooperman, B.S., Goldman, A.
Deposit date:1998-09-15
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
J.Mol.Biol., 284, 1998
1E6A
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FLUORIDE-INHIBITED SUBSTRATE COMPLEX OF SACCHAROMYCES CEREVISIAE INORGANIC PYROPHOSPHATASE
Descriptor:INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PYROPHOSPHATE 2-, ...
Authors:Heikinheimo, P., Tuominen, V., Ahonen, A.-K., Teplyakov, A., Cooperman, B.S., Baykov, A.A., Lahti, R., Goldman, A.
Deposit date:2000-08-09
Release date:2001-03-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase.
Proc. Natl. Acad. Sci. U.S.A., 98, 2001
1E9G
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STRUCTURE OF INORGANIC PYROPHOSPHATASE
Descriptor:INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION
Authors:Heikinheimo, P., Tuominen, V., Ahonen, A.-K., Teplyakov, A., Cooperman, B.S., Baykov, A.A., Lahti, R., Goldman, A.
Deposit date:2000-10-12
Release date:2001-03-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase
Proc.Natl.Acad.Sci.USA, 98, 2001
1HUJ
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REFINED STRUCTURE OF YEAST INORGANIC PYROPHOSPHATASE AND ITS K61R MUTANT
Descriptor:INORGANIC PYROPHOSPHATASE, MAGNESIUM ION
Authors:Swaminathan, K., Cooperman, B.S., Lahti, R., Voet, D.
Deposit date:1997-12-26
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined Structure of Yeast Inorganic Pyrophosphatase and its K61R Mutant
To be Published
1HUK
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REFINED STRUCTURE OF YEAST INORGANIC PYROPHOSPHATASE AND ITS K61R MUTANT
Descriptor:INORGANIC PYROPHOSPHATASE, MAGNESIUM ION
Authors:Swaminathan, K., Cooperman, B.S., Lahti, R., Voet, D.
Deposit date:1997-12-26
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined Structure of Yeast Inorganic Pyrophosphatase and its K61R Mutant
To be Published
1I74
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STREPTOCOCCUS MUTANS INORGANIC PYROPHOSPHATASE
Descriptor:PROBABLE MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, MAGNESIUM ION, ...
Authors:Merckel, M.C., Fabrichniy, I.P., Goldman, A., Lahti, R., Salminen, A.
Deposit date:2001-03-07
Release date:2001-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Streptococcus mutans pyrophosphatase: a new fold for an old mechanism.
Structure, 9, 2001
1QEZ
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SULFOLOBUS ACIDOCALDARIUS INORGANIC PYROPHOSPHATASE: AN ARCHAEL PYROPHOSPHATASE.
Descriptor:PROTEIN (INORGANIC PYROPHOSPHATASE), MAGNESIUM ION
Authors:Leppanen, V.-M., Nummelin, H., Hansen, T., Lahti, R., Schafer, G., Goldman, A.
Deposit date:1999-04-06
Release date:1999-04-14
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Sulfolobus acidocaldarius inorganic pyrophosphatase: structure, thermostability, and effect of metal ion in an archael pyrophosphatase.
Protein Sci., 8, 1999
1WPM
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STRUCTURE OF BACILLUS SUBTILIS INORGANIC PYROPHOSPHATASE
Descriptor:Manganese-dependent inorganic pyrophosphatase, SULFATE ION, TETRAETHYLENE GLYCOL
Authors:Fabrichniy, I.P., Lehtio, L., Salminen, A., Baykov, A.A., Lahti, R., Goldman, A.
Deposit date:2004-09-09
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion
Biochemistry, 43, 2004
1WPN
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CRYSTAL STRUCTURE OF THE N-TERMINAL CORE OF BACILLUS SUBTILIS INORGANIC PYROPHOSPHATASE
Descriptor:Manganese-dependent inorganic pyrophosphatase, MANGANESE (II) ION, SULFATE ION
Authors:Fabrichniy, I.P., Lehtio, L., Salminen, A., Baykov, A.A., Lahti, R., Goldman, A.
Deposit date:2004-09-09
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion
Biochemistry, 43, 2004
1WPP
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STRUCTURE OF STREPTOCOCCUS GORDONII INORGANIC PYROPHOSPHATASE
Descriptor:Probable manganese-dependent inorganic pyrophosphatase, ZINC ION, SULFATE ION, ...
Authors:Fabrichniy, I.P., Lehtio, L., Salminen, A., Baykov, A.A., Lahti, R., Goldman, A.
Deposit date:2004-09-09
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion
Biochemistry, 43, 2004
2IHP
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YEAST INORGANIC PYROPHOSPHATASE WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-09-27
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK0
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YEAST INORGANIC PYROPHOSPHATASE VARIANT E48D WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK1
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YEAST INORGANIC PYROPHOSPHATASE VARIANT Y93F WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK2
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YEAST INORGANIC PYROPHOSPHATASE VARIANT D115E WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK4
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YEAST INORGANIC PYROPHOSPHATASE VARIANT D117E WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK6
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YEAST INORGANIC PYROPHOSPHATASE VARIANT D120E WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK7
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YEAST INORGANIC PYROPHOSPHATASE VARIANT D120N WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
2IK9
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YEAST INORGANIC PYROPHOSPHATASE VARIANT D152E WITH MAGNESIUM AND PHOSPHATE
Descriptor:Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Oksanen, E., Ahonen, A.K., Tuominen, H., Tuominen, V., Lahti, R., Goldman, A., Heikinheimo, P.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
3L2B
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CRYSTAL STRUCTURE OF THE CBS AND DRTGG DOMAINS OF THE REGULATORY REGION OF CLOSTRIDIUM PERFRINGENS PYROPHOSPHATASE COMPLEXED WITH ACTIVATOR, DIADENOSINE TETRAPHOSPHATE
Descriptor:Probable manganase-dependent inorganic pyrophosphatase, BIS(ADENOSINE)-5'-TETRAPHOSPHATE
Authors:Tuominen, H., Salminen, A., Oksanen, E., Jamsen, J., Heikkila, O., Lehtio, L., Magretova, N.N., Goldman, A., Baykov, A.A., Lahti, R.
Deposit date:2009-12-15
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate.
J.Mol.Biol., 2010
3L31
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CRYSTAL STRUCTURE OF THE CBS AND DRTGG DOMAINS OF THE REGULATORY REGION OF CLOSTRIDIUM PERFRINGENS PYROPHOSPHATASE COMPLEXED WITH THE INHIBITOR, AMP
Descriptor:Probable manganase-dependent inorganic pyrophosphatase, ADENOSINE MONOPHOSPHATE
Authors:Tuominen, H., Salminen, A., Oksanen, E., Jamsen, J., Heikkila, O., Lehtio, L., Magretova, N.N., Goldman, A., Baykov, A.A., Lahti, R.
Deposit date:2009-12-16
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate.
J.Mol.Biol., 2010
1IPW
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INORGANIC PYROPHOSPHATASE FROM ESCHERICHIA COLI WITH THREE MAGNESIUM IONS
Descriptor:SOLUBLE INORGANIC PYROPHOSPHATASE, MAGNESIUM ION
Authors:Kankare, J.A., Goldman, A.
Deposit date:1996-03-04
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic identification of metal-binding sites in Escherichia coli inorganic pyrophosphatase.
Biochemistry, 35, 1996
1FAJ
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INORGANIC PYROPHOSPHATASE
Descriptor:SOLUBLE INORGANIC PYROPHOSPHATASE
Authors:Kankare, J.A., Salminen, T., Goldman, A.
Deposit date:1996-01-10
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of Escherichia coli inorganic pyrophosphatase at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
2EIP
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INORGANIC PYROPHOSPHATASE
Descriptor:SOLUBLE INORGANIC PYROPHOSPHATASE
Authors:Kankare, J.A., Salminen, T., Goldman, A.
Deposit date:1996-01-10
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Escherichia coli inorganic pyrophosphatase at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
1WGI
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STRUCTURE OF INORGANIC PYROPHOSPHATASE
Descriptor:INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION
Authors:Heikinheimo, P., Goldman, A.
Deposit date:1996-10-24
Release date:1997-11-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structural basis for pyrophosphatase catalysis.
Structure, 4, 1996
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