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1O8N
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THE ACTIVE SITE OF THE MOLYBDENUM COFACTOR BIOSYNTHETIC PROTEIN DOMAIN CNX1G
Descriptor:MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN
Authors:Kuper, J., Winking, J., Hecht, H.J., Schwarz, G., Mendel, R.R.
Deposit date:2002-11-28
Release date:2003-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Active Site of the Molybdenum Cofactor Biosynthetic Protein Domain Cnx1G
Arch.Biochem.Biophys., 411, 2003
1O8O
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THE ACTIVE SITE OF THE MOLYBDENUM COFACTOR BIOSYNTHETIC PROTEIN DOMAIN CNX1G
Descriptor:MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN
Authors:Kuper, J., Winking, J., Hecht, H.J., Schwarz, G., Mendel, R.R.
Deposit date:2002-11-28
Release date:2003-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Active Site of the Molybdenum Cofactor Biosynthetic Protein Domain Cnx1G
Arch.Biochem.Biophys., 411, 2003
1O8Q
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THE ACTIVE SITE OF THE MOLYBDENUM COFACTOR BIOSENTHETIC PROTEIN DOMAIN CNX1G
Descriptor:MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN
Authors:Kuper, J., Winking, J., Hecht, H.J., Schwarz, G., Mendel, R.R.
Deposit date:2002-11-28
Release date:2003-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Active Site of the Molybdenum Cofactor Biosynthetic Protein Domain Cnx1G
Arch.Biochem.Biophys., 411, 2003
4A15
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CRYSTAL STRUCTURE OF AN XPD DNA COMPLEX
Descriptor:ATP-DEPENDENT DNA HELICASE TA0057, 5'-D(*DTP*AP*CP*GP)-3', IRON/SULFUR CLUSTER, ...
Authors:Kuper, J., Wolski, S.C., Michels, G., Kisker, C.
Deposit date:2011-09-14
Release date:2012-02-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional and Structural Studies of the Nucleotide Excision Repair Helicase Xpd Suggest a Polarity for DNA Translocation.
Embo J., 31, 2011
1UUX
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STRUCTURE OF A MOLYBDOPTERIN-BOUND CNX1G DOMAIN LINKS MOLYBDENUM AND COPPER METABOLISM
Descriptor:MOLYBDOPTERIN BIOSYNTHESIS CNX1, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, PROPANOIC ACID, ...
Authors:Kuper, J., Llamas, A., Hecht, H.J., Mendel, R.R., Schwarz, G.
Deposit date:2004-01-12
Release date:2004-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a Molybdopterin-Bound Cnx1G Domain Links Molybdenum and Copper Metabolism
Nature, 430, 2004
1UUY
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STRUCTURE OF A MOLYBDOPTERIN-BOUND CNX1G DOMAIN LINKS MOLYBDENUM AND COPPER METABOLISM
Descriptor:MOLYBDOPTERIN BIOSYNTHESIS CNX1, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ADENOSINE MONOPHOSPHATE, ...
Authors:Kuper, J., Llamas, A., Hecht, H.J., Mendel, R.R., Schwarz, G.
Deposit date:2004-01-12
Release date:2004-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of a Molybdopterin-Bound Cnx1G Domain Links Molybdenum and Copper Metabolism
Nature, 430, 2004
1VZW
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CRYSTAL STRUCTURE OF THE BIFUNCTIONAL PROTEIN PRIA
Descriptor:PHOSPHORIBOSYL ISOMERASE A, SULFATE ION, GLYCEROL
Authors:Kuper, J., Wilmanns, M.
Deposit date:2004-05-27
Release date:2005-01-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two-Fold Repeated (Beta-Alpha)(4) Half-Barrels May Provide a Molecular Tool for Dual Substrate Specificity
Embo Rep., 6, 2005
2J1M
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P450 BM3 HEME DOMAIN IN COMPLEX WITH DMSO
Descriptor:CYTOCHROME P450 102, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ...
Authors:Kuper, J., Tuck-Seng, W., Roccatano, D., Wilmanns, M., Schwaneberg, U.
Deposit date:2006-08-14
Release date:2007-05-15
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Understanding a Mechanism of Organic Cosolvent Inactivation in Heme Monooxygenase P450 Bm-3.
J.Am.Chem.Soc., 129, 2007
2J4S
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P450 BM3 HEME DOMAIN IN COMPLEX WITH DMSO
Descriptor:BIFUNCTIONAL P-450\:NADPH-P450 REDUCTASE, PROTOPORPHYRIN IX CONTAINING FE, DI(HYDROXYETHYL)ETHER, ...
Authors:Kuper, J., Tuck-Seng, W., Roccatano, D., Wilmanns, M., Schwaneberg, U.
Deposit date:2006-09-05
Release date:2007-05-15
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Understanding a Mechanism of Organic Cosolvent Inactivation in Heme Monooxygenase P450 Bm-3.
J.Am.Chem.Soc., 129, 2007
2X7Y
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P450 BM3 F87A IN COMPLEX WITH DMSO
Descriptor:BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ...
Authors:Kuper, J., Wong, T.S., Roccatano, D., Wilmanns, M., Schwaneberg, U.
Deposit date:2010-03-04
Release date:2011-03-23
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Role of Active-Site Phe87 in Modulating the Organic Co-Solvent Tolerance of Cytochrome P450 Bm3 Monooxygenase.
Acta Crystallogr.,Sect.F, 68, 2012
2X80
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P450 BM3 F87A IN COMPLEX WITH DMSO
Descriptor:BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ...
Authors:Kuper, J., Wong, T.S., Roccatano, D., Wilmanns, M., Schwaneberg, U.
Deposit date:2010-03-05
Release date:2011-03-23
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Role of Active-Site Phe87 in Modulating the Organic Co-Solvent Tolerance of Cytochrome P450 Bm3 Monooxygenase.
Acta Crystallogr.,Sect.F, 68, 2012
2VSF
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STRUCTURE OF XPD FROM THERMOPLASMA ACIDOPHILUM
Descriptor:DNA REPAIR HELICASE RAD3 RELATED PROTEIN, IRON/SULFUR CLUSTER, CALCIUM ION
Authors:Kuper, J., Wolski, S.C., Truglio, J.J., Kisker, C.
Deposit date:2008-04-23
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Fes Cluster-Containing Nucleotide Excision Repair Helicase Xpd.
Plos Biol., 6, 2008
2X0G
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X-RAY STRUCTURE OF A DAP-KINASE CALMODULIN COMPLEX
Descriptor:DEATH-ASSOCIATED PROTEIN KINASE 1, CALMODULIN, SULFATE ION, ...
Authors:Kuper, J., De Diego, I., Lehmann, F., Wilmanns, M.
Deposit date:2009-12-08
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis of the Death-Associated Protein Kinase-Calcium/Calmodulin Regulator Complex.
Sci.Signal, 3, 2010
2Y85
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE WITH BOUND RCDRP
Descriptor:PHOSPHORIBOSYL ISOMERASE A, SODIUM ION, CHLORIDE ION, ...
Authors:Kuper, J., Geerlof, A., Wilmanns, M.
Deposit date:2011-02-03
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Bisubstrate Specificity in Histidine/Tryptophan Biosynthesis Isomerase from Mycobacterium Tuberculosis by Active Site Metamorphosis.
Proc.Natl.Acad.Sci.USA, 108, 2011
2Y88
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE (VARIANT D11N) WITH BOUND PRFAR
Descriptor:PHOSPHORIBOSYL ISOMERASE A, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE
Authors:Kuper, J., Due, A.V., Geerlof, A., Wilmanns, M.
Deposit date:2011-02-03
Release date:2011-03-02
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Bisubstrate Specificity in Histidine/Tryptophan Biosynthesis Isomerase from Mycobacterium Tuberculosis by Active Site Metamorphosis.
Proc.Natl.Acad.Sci.USA, 108, 2011
5A3D
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STRUCTURAL INSIGHTS INTO THE RECOGNITION OF CISPLATIN AND AAF-DG LESIONS BY RAD14 (XPA)
Descriptor:DNA REPAIR PROTEIN RAD14, 5'-D(*DTP*CP*TP*CP*TP*AP*C 8FGP*TP*CP*AP*TP*CP*DAP*CP)-3', 5'-D(*DG 5IUP*GP*A 5IUP*GP*AP*CP*G 5IUP*AP*GP*AP*DGP*AP)-3', ...
Authors:Kuper, J., Koch, S.C., Gasteiger, K.L., Wichlein, N., Schneider, S., Kisker, C., Carell, T.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesion by Rad14 (Xpa).
Proc.Natl.Acad.Sci.USA, 112, 2015
4F9Z
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CRYSTAL STRUCTURE OF HUMAN ERP27
Descriptor:Endoplasmic reticulum resident protein 27, ACETATE ION, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
Authors:Kober, F.X., Koelmel, W., Kuper, J., Schindelin, H.
Deposit date:2012-05-21
Release date:2012-12-05
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Protein-Disulfide Isomerase Family Member ERp27 Provides Insights into Its Substrate Binding Capabilities.
J.Biol.Chem., 288, 2013
5G2O
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YERSINIA PESTIS FABV VARIANT T276A
Descriptor:ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-11
Release date:2016-05-25
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
5JAI
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YERSINIA PESTIS FABV VARIANT T276G
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, ...
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-12
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JAM
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YERSINIA PESTIS FABV VARIANT T276V
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-12
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JAQ
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YERSINIA PESTIS FABV VARIANT T276C
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-12
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5NUS
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STRUCTURE OF A MINIMAL COMPLEX BETWEEN P44 AND P34 FROM CHAETOMIUM THERMOPHILUM
Descriptor:p34, p44, ZINC ION
Authors:Koelmel, W., Schoenwetter, E., Kuper, J., Schmitt, D.R., Kisker, C.
Deposit date:2017-05-02
Release date:2017-10-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Nucleic Acids Res., 45, 2017
5OBZ
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LOW RESOLUTION STRUCTURE OF THE P34CT/P44CT MINIMAL COMPLEX
Descriptor:Putative transcription factor, ZINC ION
Authors:Schoenwetter, E., Koelmel, W., Schmitt, D.R., Kuper, J., Kisker, C.
Deposit date:2017-06-29
Release date:2017-10-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Nucleic Acids Res., 45, 2017
1H4C
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BIOCHEMICAL AND STRUCTURAL ANALYSIS OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOBA
Descriptor:MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A, LITHIUM ION, CITRIC ACID
Authors:Guse, A., Stevenson, C.E.M., Kuper, J., Buchanan, G., Schwarz, G., Mendel, R.R., Lawson, D.M., Palmer, T.
Deposit date:2003-02-26
Release date:2003-05-08
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba
J.Biol.Chem., 278, 2003
1H4D
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BIOCHEMICAL AND STRUCTURAL ANALYSIS OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOBA
Descriptor:MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A, LITHIUM ION, CITRIC ACID
Authors:Guse, A., Stevenson, C.E.M., Kuper, J., Buchanan, G., Schwarz, G., Mendel, R.R., Lawson, D.M., Palmer, T.
Deposit date:2003-02-26
Release date:2003-05-08
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba
J.Biol.Chem., 278, 2003