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1DMJ
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 5,6-CYCLIC-TETRAHYDROPTERIDINE
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
Authors:Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
1DMK
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 4-AMINO-6-PHENYL-TETRAHYDROPTERIDINE
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
Authors:Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
1DMI
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 6S-H4B
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Kotsonis, P., Pfleiderer, W., Schmidt, H.H.H.W., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with the Pterin Analogues
To be Published
1ZVI
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H.
Deposit date:2005-06-02
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
1ZVL
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN COMPLEXED WITH NATURAL SUBSTRATE L-ARG.
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H.
Deposit date:2005-06-02
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005