3OLM
| Structure and Function of a Ubiquitin Binding Site within the Catalytic Domain of a HECT Ubiquitin Ligase | Descriptor: | E3 ubiquitin-protein ligase RSP5, Ubiquitin | Authors: | Kim, H.C, Steffen, A, Chen, J, Huibregtse, J.M. | Deposit date: | 2010-08-26 | Release date: | 2011-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Structure and function of a HECT domain ubiquitin-binding site. Embo Rep., 12, 2011
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4M6R
| Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme | Descriptor: | Methylthioribulose-1-phosphate dehydratase, ZINC ION | Authors: | Kang, W, Hong, S.H, Lee, H.M, Kim, N.Y, Lim, Y.C, Le, L.T.M, Lim, B, Kim, H.C, Kim, T.Y, Ashida, H, Yokota, A, Hah, S.S, Chun, K.H, Jung, Y.K, Yang, J.K. | Deposit date: | 2013-08-10 | Release date: | 2014-01-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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7QI8
| CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE AND INHIBITOR | Descriptor: | 2-azanyl-6-[(1~{S},7~{S})-2,2-bis(fluoranyl)-7-oxidanyl-cycloheptyl]-4-methoxy-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one, LYSINE, Lysine--tRNA ligase 1 | Authors: | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | Deposit date: | 2021-12-14 | Release date: | 2022-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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7QHN
| CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE and an inhibitor | Descriptor: | 6-azanyl-2-cyclohexyl-4-fluoranyl-1~{H}-pyrrolo[3,4-c]pyridin-3-one, LYSINE, Lysine--tRNA ligase 1 | Authors: | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | Deposit date: | 2021-12-13 | Release date: | 2022-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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7QH8
| CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE | Descriptor: | GLYCEROL, LYSINE, Lysine--tRNA ligase 1 | Authors: | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | Deposit date: | 2021-12-10 | Release date: | 2022-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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5DMS
| Mouse Polo-box domain and Emi2 (169-177) | Descriptor: | F-box only protein 43, Serine/threonine-protein kinase PLK1 | Authors: | Namgoong, S. | Deposit date: | 2015-09-09 | Release date: | 2015-10-28 | Method: | X-RAY DIFFRACTION (1.89999 Å) | Cite: | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization. Sci Rep, 5, 2015
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5DNJ
| Mouse Polo-box domain and Peptide analog 702 | Descriptor: | Serine/threonine-protein kinase PLK1, peptide 707-56A-SER-TPO-NH2 | Authors: | Namgoong, S, Han, Y.H. | Deposit date: | 2015-09-10 | Release date: | 2016-02-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization. Sci Rep, 5, 2015
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5DMV
| Polo-box domain of Mouse Polo-like kinase 1 complexed with Emi2 (146-177) | Descriptor: | F-box only protein 43, NICKEL (II) ION, Serine/threonine-protein kinase PLK1 | Authors: | Namgoong, S. | Deposit date: | 2015-09-09 | Release date: | 2015-10-28 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization. Sci Rep, 5, 2015
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1L9M
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1L9N
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1NUF
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1M2K
| Sir2 homologue F159A mutant-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1NUG
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1NUD
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1M2G
| Sir2 homologue-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2J
| Sir2 homologue H80N mutant-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2N
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1M2H
| Sir2 homologue S24A mutant-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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