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5AXC
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BU of 5axc by Molmil
Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin
Descriptor: (2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentanone, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Kusakabe, Y, Ishihara, M, Tanaka, N.
Deposit date:2015-07-24
Release date:2016-07-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin
To Be Published
5AXD
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BU of 5axd by Molmil
Crystal structure of mouse SAHH complexed with ribavirin
Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kusakabe, Y, Ishihara, M, Tanaka, N.
Deposit date:2015-07-24
Release date:2016-07-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of mouse SAHH complexed with ribavirin
To Be Published
5AXB
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BU of 5axb by Molmil
Crystal structure of mouse SAHH complexed with noraristeromycin
Descriptor: (1S,2R,3S,4R)-4-(6-aminopurin-9-yl)cyclopentane-1,2,3-triol, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Kusakabe, Y, Ishihara, M, Tanaka, N.
Deposit date:2015-07-24
Release date:2016-07-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of mouse SAHH complexed with noraristeromycin
To Be Published
5AXA
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BU of 5axa by Molmil
Crystal structure of mouse SAHH complexed with adenosine
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Kusakabe, Y, Ishihara, M, Tanaka, N.
Deposit date:2015-07-24
Release date:2016-07-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of mouse SAHH complexed with adenosine
To Be Published
4X8Y
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BU of 4x8y by Molmil
Crystal structure of human PGRMC1 cytochrome b5-like domain
Descriptor: Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nakane, T, Yamamoto, T, Shimamura, T, Kobayashi, T, Kabe, Y, Suematsu, M.
Deposit date:2014-12-11
Release date:2016-03-23
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nat Commun, 7, 2016
6ILI
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BU of 6ili by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 6.5
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2018-10-18
Release date:2018-11-07
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
4WCO
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BU of 4wco by Molmil
Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A
Descriptor: ACETATE ION, C-type lectin domain family 2 member D, SULFATE ION, ...
Authors:Kita, S, Matsubara, H, Kasai, Y, Tamaoki, T, Okabe, Y, Fukuhara, H, Kamishikiryo, J, Ose, T, Kuroki, K, Maenaka, K.
Deposit date:2014-09-05
Release date:2015-06-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A
Eur.J.Immunol., 45, 2015
5WS7
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BU of 5ws7 by Molmil
Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-12-05
Release date:2017-01-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
6IMF
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BU of 6imf by Molmil
Crystal structure of TOXIN/ANTITOXIN complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cysteine-rich venom protein triflin, GLYCEROL, ...
Authors:Shioi, N, Tadokoro, T, Shioi, S, Hu, Y, Kurahara, L.H, Okabe, Y, Matsubara, H, Kita, S, Ose, T, Kuroki, K, Maenaka, K, Terada, S.
Deposit date:2018-10-22
Release date:2018-12-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the complex between venom toxin and serum inhibitor from Viperidae snake.
J. Biol. Chem., 294, 2019
5GHI
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BU of 5ghi by Molmil
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.211 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHO
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BU of 5gho by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 8-oxo-dGTP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.191 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHN
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BU of 5ghn by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.391 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHM
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BU of 5ghm by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHQ
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BU of 5ghq by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.181 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHJ
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BU of 5ghj by Molmil
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHP
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BU of 5ghp by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP
Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION
Authors:Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.192 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
1WDY
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BU of 1wdy by Molmil
Crystal structure of ribonuclease
Descriptor: 2-5A-dependent ribonuclease, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE
Authors:Tanaka, N, Nakanishi, M, Kusakabe, Y, Goto, Y, Kitade, Y, Nakamura, K.T.
Deposit date:2004-05-19
Release date:2004-10-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L
Embo J., 23, 2004
5JR8
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BU of 5jr8 by Molmil
Disposal of Iron by a Mutant form of Siderocalin NGAL
Descriptor: GLYCEROL, Neutrophil gelatinase-associated lipocalin, PHOSPHATE ION
Authors:Rupert, P.B, Strong, R.K, Barasch, J, Hollman, M, Deng, R, Hod, E.A, Abergel, R, Allred, B, Xu, K, Darrah, S, Tekabe, Y, Perlstein, A, Bruck, E, Stauber, J, Corbin, K, Buchen, C, Slavkovich, V, Graziano, J, Spitalnik, S, Qiu, A.
Deposit date:2016-05-05
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Disposal of iron by a mutant form of lipocalin 2.
Nat Commun, 7, 2016
1IRY
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BU of 1iry by Molmil
Solution structure of the hMTH1, a nucleotide pool sanitization enzyme
Descriptor: hMTH1
Authors:Mishima, M, Itoh, N, Sakai, Y, Kamiya, H, Nakabeppu, Y, Shirakawa, M.
Deposit date:2001-10-25
Release date:2003-12-23
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates
J.Biol.Chem., 279, 2004
1V8B
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BU of 1v8b by Molmil
Crystal structure of a hydrolase
Descriptor: ADENOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, adenosylhomocysteinase
Authors:Tanaka, N, Nakanishi, M, Kusakabe, Y, Shiraiwa, K, Kitade, Y, Nakamura, K.T.
Deposit date:2004-01-03
Release date:2004-10-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of S-Adenosyl-l-Homocysteine Hydrolase from the Human Malaria Parasite Plasmodium falciparum
J.Mol.Biol., 343, 2004
1J2F
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BU of 1j2f by Molmil
X-ray crystal structure of IRF-3 and its functional implications
Descriptor: Interferon regulatory factor 3
Authors:Takahasi, K, Noda, N, Horiuchi, M, Mori, M, Okabe, Y, Fukuhara, Y, Terasawa, H, Fujita, T, Inagaki, F.
Deposit date:2003-01-04
Release date:2003-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of IRF-3 and its functional implications.
Nat.Struct.Biol., 10, 2003
3WH3
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BU of 3wh3 by Molmil
human Mincle, ligand free form
Descriptor: C-type lectin domain family 4 member E, CALCIUM ION
Authors:Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K.
Deposit date:2013-08-21
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
3WH2
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BU of 3wh2 by Molmil
Human Mincle in complex with citrate
Descriptor: C-type lectin domain family 4 member E, CALCIUM ION, CITRATE ANION
Authors:Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K.
Deposit date:2013-08-21
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
3WHD
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BU of 3whd by Molmil
C-type lectin, human MCL
Descriptor: C-type lectin domain family 4 member D, CALCIUM ION
Authors:Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K.
Deposit date:2013-08-24
Release date:2013-10-23
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
1KOL
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BU of 1kol by Molmil
Crystal structure of formaldehyde dehydrogenase
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ZINC ION, ...
Authors:Tanaka, N, Kusakabe, Y, Ito, K, Yoshimoto, T, Nakamura, K.T.
Deposit date:2001-12-21
Release date:2002-12-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of Formaldehyde Dehydrogenase from Pseudomonas putida: the Structural Origin of the Tightly Bound Cofactor in Nicotinoprotein Dehydrogenases
J.mol.biol., 324, 2002

 

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