8Q40
| Crystal structure of cA4 activated Can2 in complex with a cleaved DNA substrate | Descriptor: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*CP*A)-3'), DUF1887 family protein, ... | Authors: | Jungfer, K, Sigg, A, Jinek, M. | Deposit date: | 2023-08-04 | Release date: | 2023-11-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
|
|
8Q42
| Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-A DNA | Descriptor: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*AP*AP*AP*A)-3'), DUF1887 family protein, ... | Authors: | Jungfer, K, Sigg, A, Jinek, M. | Deposit date: | 2023-08-04 | Release date: | 2023-11-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
|
|
8Q41
| Crystal structure of Can2 (E341A) bound to cA4 and TTTAAA ssDNA | Descriptor: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*AP*AP*A)-3'), DUF1887 family protein, ... | Authors: | Jungfer, K, Sigg, A, Jinek, M. | Deposit date: | 2023-08-04 | Release date: | 2023-11-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
|
|
8Q43
| Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-C DNA | Descriptor: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*CP*CP*CP*CP*C)-3'), DUF1887 family protein, ... | Authors: | Jungfer, K, Sigg, A, Jinek, M. | Deposit date: | 2023-08-04 | Release date: | 2023-11-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
|
|
8Q44
| Crystal structure of cA4-bound Can2 (E364R) in complex with oligo-T DNA | Descriptor: | Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*T)-3'), DUF1887 family protein, ... | Authors: | Jungfer, K, Sigg, A, Jinek, M. | Deposit date: | 2023-08-04 | Release date: | 2023-11-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res., 52, 2024
|
|
8Q3Z
| |
8Q3Y
| |
2IXZ
| Solution structure of the apical stem-loop of the human hepatitis B virus encapsidation signal | Descriptor: | 5'-R(*GP*CP*UP*GP*UP*GP*CP*CP)-3' | Authors: | Flodell, S, Petersen, M, Girard, F, Zdunek, J, Kidd-Ljunggren, K, Schleucher, J, Wijmenga, S.S. | Deposit date: | 2006-07-11 | Release date: | 2006-09-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the apical stem-loop of the human hepatitis B virus encapsidation signal. Nucleic Acids Res., 34, 2006
|
|
2IXY
| Solution structure of the apical stem-loop of the human hepatitis B virus encapsidation signal | Descriptor: | 5'-R(*GP*GP*CP*CP*UP*CP*CP*AP*AP*GP *CP*UP*GP*UP*GP*CP*CP*UP*UP*GP*GP*GP*UP*GP*GP*CP*C)-3' | Authors: | Flodell, S, Petersen, M, Girard, F, Zdunek, J, Kidd-Ljunggren, K, Schleucher, J, Wijmenga, S.S. | Deposit date: | 2006-07-11 | Release date: | 2006-09-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the apical stem-loop of the human hepatitis B virus encapsidation signal. Nucleic Acids Res., 34, 2006
|
|
6ILQ
| Crystal structure of PPARgamma with compound BR101549 | Descriptor: | Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma, ethyl [2-butyl-6-oxo-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}-4-(propan-2-yl)-1,6-dihydropyrimidin-5-yl]acetate | Authors: | Hong, E, Jang, T.H, Chin, J, Kim, K.H, Jung, W, Kim, S.H. | Deposit date: | 2018-10-19 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.408 Å) | Cite: | Identification of BR101549 as a lead candidate of non-TZD PPAR gamma agonist for the treatment of type 2 diabetes: Proof-of-concept evaluation and SAR. Bioorg.Med.Chem.Lett., 29, 2019
|
|
7S4U
| Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, Target strand, ... | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | Deposit date: | 2021-09-09 | Release date: | 2022-03-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
|
|
7S4V
| Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | Deposit date: | 2021-09-09 | Release date: | 2022-03-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
|
|
7S4X
| Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | Deposit date: | 2021-09-09 | Release date: | 2022-03-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
|
|
5NV8
| Structural basis for EarP-mediated arginine glycosylation of translation elongation factor EF-P | Descriptor: | 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, EF-P arginine 32 rhamnosyl-transferase | Authors: | Macosek, J, Krafczyk, R, Jagtap, P.K.A, Lassaka, J, Hennig, J. | Deposit date: | 2017-05-03 | Release date: | 2017-10-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.294 Å) | Cite: | Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P. MBio, 8, 2017
|
|
2M3G
| Structure of Anabaena Sensory Rhodopsin Determined by Solid State NMR Spectroscopy | Descriptor: | Anabaena Sensory Rhodopsin, RETINAL | Authors: | Wang, S, Munro, R.A, Shi, L, Kawamura, I, Okitsu, T, Wada, A, Kim, S, Jung, K, Brown, L.S, Ladizhansky, V. | Deposit date: | 2013-01-17 | Release date: | 2013-08-21 | Last modified: | 2023-06-14 | Method: | SOLID-STATE NMR | Cite: | Solid-state NMR spectroscopy structure determination of a lipid-embedded heptahelical membrane protein. Nat.Methods, 10, 2013
|
|
5JU7
| DNA BINDING DOMAIN OF E.COLI CADC | Descriptor: | Transcriptional activator CadC, ZINC ION | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | Deposit date: | 2016-05-10 | Release date: | 2017-04-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator. Sci Rep, 7, 2017
|
|
3LY8
| |
3LYA
| |
3LY9
| |
3LY7
| |
5B7U
| |
5B89
| |
5B7S
| |
5B87
| |
6Q3Q
| Arabidopsis OM64 TPR domain | Descriptor: | GLY-SER-LYS-MET-GLU-GLU-VAL-ASP, GLYCEROL, Outer envelope protein 64, ... | Authors: | Schwenkert, S. | Deposit date: | 2018-12-04 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation of the outer membrane mitochondrial protein OM64 influences protein import into mitochondria. Mitochondrion, 44, 2019
|
|