Author results

2J0N
  • Download 2j0n
  • View 2j0n
Molmil generated image of 2j0n
A PROTEOLYTICALLY TRUNCATED FORM OF SHIGELLA FLEXNERI IPAD
Descriptor:INVASIN IPAD
Authors:Johnson, S., Roversi, P., Lea, S.M.
Deposit date:2006-08-03
Release date:2006-11-02
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.
J. Biol. Chem., 282, 2007
2J0O
  • Download 2j0o
  • View 2j0o
Molmil generated image of 2j0o
SHIGELLA FLEXNERI IPAD
Descriptor:INVASIN IPAD, GLYCEROL
Authors:Johnson, S., Roversi, P., Lea, S.M.
Deposit date:2006-08-04
Release date:2006-11-02
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.
J. Biol. Chem., 282, 2007
2J9T
  • Download 2j9t
  • View 2j9t
Molmil generated image of 2j9t
BIPD OF BURKHOLDERIA PSEUDOMALLEI
Descriptor:MEMBRANE ANTIGEN, BORIC ACID, CITRATE ANION
Authors:Johnson, S., Roversi, P., Field, T., Deane, J.E., Galyov, E., Lea, S.M.
Deposit date:2006-11-16
Release date:2006-11-20
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
6R69
  • Download 6r69
  • View 6r69
Molmil generated image of 6r69
IMPROVED MAP OF THE FLIPQR COMPLEX THAT FORMS THE CORE OF THE SALMONELLA TYPE III SECRETION SYSTEM EXPORT APPARATUS.
Descriptor:Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliR, Flagellar biosynthetic protein FliQ
Authors:Johnson, S., Kuhlen, L., Abrusci, P., Lea, S.M.
Deposit date:2019-03-26
Release date:2019-05-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems.
Mbio, 10, 2019
6R6B
  • Download 6r6b
  • View 6r6b
Molmil generated image of 6r6b
STRUCTURE OF THE CORE SHIGELLA FLEXNERI TYPE III SECRETION SYSTEM EXPORT GATE COMPLEX SCTRST (SPA24/SPA9/SPA29).
Descriptor:Surface presentation of antigens protein SpaP, Surface presentation of antigens protein SpaR, Surface presentation of antigens protein SpaQ
Authors:Johnson, S., Kuhlen, L., Deme, J.C., Abrusci, P., Lea, S.M.
Deposit date:2019-03-26
Release date:2019-05-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems.
Mbio, 10, 2019
2JAA
  • Download 2jaa
  • View 2jaa
Molmil generated image of 2jaa
SEMET SUBSTITUTED SHIGELLA FLEXNERI IPAD
Descriptor:INVASIN IPAD
Authors:Johnson, S., Roversi, P., Espina, M., Olive, A., Deane, J.E., Birket, S., Field, T., Picking, W.D., Blocker, A.J., Galyov, E.E., Picking, W.L., Lea, S.M.
Deposit date:2006-11-24
Release date:2006-11-30
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
4AYD
  • Download 4ayd
  • View 4ayd
Molmil generated image of 4ayd
STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 1 R106A MUTANT
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN, 1,2-ETHANEDIOL
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-20
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules
Plos Pathog., 8, 2012
4AYE
  • Download 4aye
  • View 4aye
Molmil generated image of 4aye
STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 1 E283AE304A MUTANT
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN, 1,2-ETHANEDIOL
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-20
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4AYI
  • Download 4ayi
  • View 4ayi
Molmil generated image of 4ayi
STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 3 WILD TYPE
Descriptor:COMPLEMENT FACTOR H, LIPOPROTEIN GNA1870 CCOMPND 7, 1,2-ETHANEDIOL
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-21
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4AYM
  • Download 4aym
  • View 4aym
Molmil generated image of 4aym
STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 3 P106A MUTANT
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-21
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4AYN
  • Download 4ayn
  • View 4ayn
Molmil generated image of 4ayn
STRUCTURE OF THE C-TERMINAL BARREL OF NEISSERIA MENINGITIDIS FHBP VARIANT 2
Descriptor:FACTOR H-BINDING PROTEIN, SULFATE ION
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-21
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4BIK
  • Download 4bik
  • View 4bik
Molmil generated image of 4bik
STRUCTURE OF A DISULFIDE LOCKED MUTANT OF INTERMEDILYSIN WITH HUMAN CD59
Descriptor:INTERMEDILYSIN, CD59 GLYCOPROTEIN
Authors:Johnson, S., Brooks, N.J., Smith, R.A.G., Lea, S.M., Bubeck, D.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.494 Å)
Cite:Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59
Cell Rep., 3, 2013
6SCN
  • Download 6scn
  • View 6scn
Molmil generated image of 6scn
33MER STRUCTURE OF THE SALMONELLA FLAGELLA MS-RING PROTEIN FLIF
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-07-24
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system
To Be Published
6SD1
  • Download 6sd1
  • View 6sd1
Molmil generated image of 6sd1
STRUCTURE OF THE RBM3/COLLAR REGION OF THE SALMONELLA FLAGELLA MS-RING PROTEIN FLIF WITH 33-FOLD SYMMETRY APPLIED
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-07-26
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system.
To Be Published
6SD2
  • Download 6sd2
  • View 6sd2
Molmil generated image of 6sd2
STRUCTURE OF THE RBM2INNER REGION OF THE SALMONELLA FLAGELLA MS-RING PROTEIN FLIF WITH 21-FOLD SYMMETRY APPLIED.
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-07-26
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system
To Be Published
6SD3
  • Download 6sd3
  • View 6sd3
Molmil generated image of 6sd3
34MER STRUCTURE OF THE SALMONELLA FLAGELLA MS-RING PROTEIN FLIF
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-07-26
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system
To Be Published
6SD4
  • Download 6sd4
  • View 6sd4
Molmil generated image of 6sd4
STRUCTURE OF THE RBM3/COLLAR REGION OF THE SALMONELLA FLAGELLA MS-RING PROTEIN FLIF WITH 34-FOLD SYMMETRY APPLIED
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-07-26
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system
To Be Published
6SD5
  • Download 6sd5
  • View 6sd5
Molmil generated image of 6sd5
STRUCTURE OF THE RBM2 INNER RING OF SALMONELLA FLAGELLA MS-RING PROTEIN FLIF WITH 22-FOLD SYMMETRY APPLIED
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-07-26
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system
To Be Published
6TRE
  • Download 6tre
  • View 6tre
Molmil generated image of 6tre
STRUCTURE OF THE RBM3/COLLAR REGION OF THE SALMONELLA FLAGELLA MS-RING PROTEIN FLIF WITH 32-FOLD SYMMETRY APPLIED
Descriptor:Flagellar M-ring protein
Authors:Johnson, S., Fong, Y.H., Deme, J.C., Furlong, E.J., Kuhlen, L., Lea, S.M.
Deposit date:2019-12-18
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system.
To Be Published
2IXR
  • Download 2ixr
  • View 2ixr
Molmil generated image of 2ixr
BIPD OF BURKHOLDERIA PSEUDOMALLEI
Descriptor:MEMBRANE ANTIGEN
Authors:Roversi, P., Johnson, S., Field, T., Deane, J.E., Galyov, E.E., Lea, S.M.
Deposit date:2006-07-10
Release date:2006-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
5NQP
  • Download 5nqp
  • View 5nqp
Molmil generated image of 5nqp
STRUCTURE OF A FHBP(V1.4):PORA(P1.16) CHIMERA. FUSION AT FHBP POSITION 151.
Descriptor:Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Johnson, S., Hollingshead, S., Lea, S.M., Tang, C.M.
Deposit date:2017-04-20
Release date:2018-02-28
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
5NQY
  • Download 5nqy
  • View 5nqy
Molmil generated image of 5nqy
STRUCTURE OF A FHBP(V1.4):PORA(P1.16) CHIMERA. FUSION AT FHBP POSITION 309.
Descriptor:Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001
Authors:Johnson, S., Hollingshead, S., Lea, S.M., Tang, C.M.
Deposit date:2017-04-21
Release date:2018-02-28
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
5NQZ
  • Download 5nqz
  • View 5nqz
Molmil generated image of 5nqz
STRUCTURE OF A FHBP(V1.1):PORA(P1.16) CHIMERA. FUSION AT FHBP POSITION 309.
Descriptor:Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein, ZINC ION, ACETATE ION, ...
Authors:Johnson, S., Hollingshead, S., Lea, S.M., Tang, C.M.
Deposit date:2017-04-21
Release date:2018-02-28
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
2VJ2
  • Download 2vj2
  • View 2vj2
Molmil generated image of 2vj2
HUMAN JAGGED-1, DOMAINS DSL AND EGFS1-3
Descriptor:JAGGED-1, D-MALATE
Authors:Johnson, S., Cordle, J., Tay, J.Z., Roversi, P., Handford, P.A., Lea, S.M.
Deposit date:2007-12-06
Release date:2008-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
2VJ3
  • Download 2vj3
  • View 2vj3
Molmil generated image of 2vj3
HUMAN NOTCH-1 EGFS 11-13
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, SODIUM ION, ...
Authors:Johnson, S., Cordle, J., Tay, J.Z., Roversi, P., Lea, S.M.
Deposit date:2007-12-06
Release date:2008-07-29
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008