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4AEL
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PDE10A IN COMPLEX WITH THE INHIBITOR AZ5
Descriptor:CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ZINC ION, ...
Authors:Bauer, U., Giordanetto, F., Bauer, M., OMahony, G., Johansson, K.E., Knecht, W., Hartleib-Geschwindner, J., Toppner Carlsson, E., Enroth, C., Sjogren, T.
Deposit date:2012-01-11
Release date:2012-01-25
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of 4-Hydroxy-1,6-Naphthyridine-3-Carbonitrile Derivatives as Novel Pde10A Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
5J7D
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COMPUTATIONALLY DESIGNED THIOREDOXIN DF106
Descriptor:Designed Thioredoxin dF106, COPPER (II) ION
Authors:Horowitz, S., Johansen, N., Olsen, J.G., Winther, J.R.
Deposit date:2016-04-06
Release date:2016-10-05
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template.
J.Mol.Biol., 428, 2016