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5DDT
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CRYSTAL STRUCTURE OF ISPD FROM BACILLUS SUBTILIS AT 1.80 ANGSTROMS RESOLUTION, CRYSTAL FORM I
Descriptor:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Authors:Jin, Y., Liu, Z.C., Wang, G.G.
Deposit date:2015-08-25
Release date:2016-08-31
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Sci Rep, 6, 2016
5DDV
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CRYSTAL STRUCTURE OF ISPD FROM BACILLUS SUBTILIS AT 2.30 ANGSTROMS RESOLUTION, CRYSTAL FORM II
Descriptor:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Authors:Jin, Y., Liu, Z.C., Wang, G.G.
Deposit date:2015-08-25
Release date:2016-08-31
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Sci Rep, 6, 2016
5HS2
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CRYSTAL STRUCTURE OF ISPD COMPLEXED WITH CTP AND MG2+ FROM BACILLUS SUBTILIS AT 1.90 ANGSTROMS RESOLUTION
Descriptor:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Jin, Y., Liu, Z.C., Wang, G.G.
Deposit date:2016-01-24
Release date:2016-11-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Sci Rep, 6, 2016
1IHI
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CRYSTAL STRUCTURE OF HUMAN TYPE III 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE/BILE ACID BINDING PROTEIN (AKR1C2) COMPLEXED WITH NADP+ AND URSODEOXYCHOLATE
Descriptor:3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISO-URSODEOXYCHOLIC ACID
Authors:Jin, Y., Stayrook, S.E., Albert, R.H., Palackal, N.T., Penning, T.M., Lewis, M.
Deposit date:2001-04-19
Release date:2001-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.
Biochemistry, 40, 2001
5G0M
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BETA-GLUCURONIDASE WITH AN ACTIVITY-BASED PROBE (N-ACYL CYCLOPHELLITOL AZIRIDINE) BOUND
Descriptor:BETA-GLUCURONIDASE, PHOSPHATE ION, (1S,2R,3R,4S,6S)-6-[(8-azidooctanoyl)amino]-2,3,4-trihydroxycyclohexane-1-carboxylate
Authors:Jin, Y., Wu, L., Jiang, J.B., Overkleeft, H.S., Davies, G.J.
Deposit date:2016-03-21
Release date:2017-04-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of a Bacteria Beta-Glucuronidase in Gh79 Family
To be Published
5JTS
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STRUCTURE OF A BETA-1,4-MANNANASE, SSGH134.
Descriptor:beta-1,4-mannanase, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:Jin, Y., Petricevic, M., Goddard-Borger, E.D., Williams, S.J., Davies, G.J.
Deposit date:2016-05-09
Release date:2016-11-16
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
ACS Cent Sci, 2, 2016
5JU9
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STRUCTURE OF A BETA-1,4-MANNANASE, SSGH134, IN COMPLEX WITH MAN3.
Descriptor:beta-1,4-mannanase, BETA-D-MANNOSE, ALPHA-D-MANNOSE, ...
Authors:Jin, Y., Petricevic, M., Goddard-Borger, E.D., Williams, S.J., Davies, G.J.
Deposit date:2016-05-10
Release date:2016-11-16
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
ACS Cent Sci, 2, 2016
5JUG
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STRUCTURE OF AN INACTIVE (E45Q) VARIANT OF A BETA-1,4-MANNANASE, SSGH134, IN COMPLEX WITH MAN5
Descriptor:beta-1,4-mannanase, BETA-D-MANNOSE, ALPHA-D-MANNOSE, ...
Authors:Jin, Y., Petricevic, M., Goddard-Borger, E.D., Williams, S.J., Davies, G.J.
Deposit date:2016-05-10
Release date:2016-11-16
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
ACS Cent Sci, 2, 2016
5AED
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A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31
Descriptor:ALPHA-GLUCOSIDASE YIHQ, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION
Authors:Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.
Deposit date:2015-08-28
Release date:2016-02-10
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12, 2016
5AEE
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A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31
Descriptor:ALPHA-GLUCOSIDASE YIHQ, CALCIUM ION, 4-NITROPHENYL-ALPHA-D-SULFOQUINOVOSIDE, ...
Authors:Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.
Deposit date:2015-08-28
Release date:2016-02-10
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12, 2016
5AEG
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A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31.
Descriptor:ALPHA-GLUCOSIDASE YIHQ, CALCIUM ION, CHLORIDE ION, ...
Authors:Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.
Deposit date:2015-08-30
Release date:2016-02-10
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12, 2016
5FOO
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6-PHOSPHO-BETA-GLUCOSIDASE
Descriptor:6-PHOSPHO-BETA-D GLYCOSIDASE, 6-PHOSPHOCYCLOPHELLITOL, 1,2-ETHANEDIOL, ...
Authors:Jin, Y., Kwan, D.H., Withers, S.G., Davies, G.J.
Deposit date:2015-11-24
Release date:2016-02-17
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Chemoenzymatic Synthesis of 6-Phospho-Cyclophellitol as a Novel Probe of 6-Phospho-Beta-Glucosidases.
FEBS Lett., 590, 2016
5G0Q
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BETA-GLUCURONIDASE WITH AN ACTIVITY-BASED PROBE (N-ALKYL CYCLOPHELLITOL AZIRIDINE) BOUND
Descriptor:BETA-GLUCURONIDASE, (1R,2S,3R,4S,5S,6R)-7-(8-AZIDOOCTYL)-3,4,5-TRIHYDROXY-, GLYCEROL
Authors:Jin, Y., Wu, L., Jiang, J.B., Overkleeft, H.S., Davies, G.J.
Deposit date:2016-03-22
Release date:2017-04-12
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5L77
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A GLYCOSIDE HYDROLASE MUTANT WITH AN UNREACTED ACTIVITY BASED PROBE BOUND
Descriptor:beta-glucuronidase, PHOSPHATE ION, (1~{R},2~{S},3~{R},4~{S},5~{S},6~{R})-7-[8-[(azanylidene-{4}-azanylidene)amino]octyl]-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, ...
Authors:Jin, Y., Wu, L., Jiang, J.B., Overkleeft, H.S., Davies, G.J.
Deposit date:2016-06-02
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5M77
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A GH76 FAMILY ENZYME STRUCTURE
Descriptor:Alpha-1,6-mannanase, 1,2-ETHANEDIOL, (2~{R},3~{S},4~{S},5~{S},6~{R})-2-[[(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methylsulfanyl]-6-(hydroxymethyl)oxane-3,4,5-triol, ...
Authors:Jin, Y., Williams, S., Davies, G.
Deposit date:2016-10-26
Release date:2017-08-09
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-alpha-mannanase inhibitor.
Chem. Commun. (Camb.), 53, 2017
5N0F
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THE CATALYTIC DOMAIN, BCGH76, OF BACILLUS CIRCULANS AMAN6 IN COMPLEX WITH 1,6-MANSIFG
Descriptor:Alpha-1,6-mannanase, (2~{R},3~{S},4~{S},5~{S},6~{R})-2-[[(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methylsulfanyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Authors:Jin, Y., Williams, S., Davies, G.
Deposit date:2017-02-02
Release date:2017-08-09
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-alpha-mannanase inhibitor.
Chem. Commun. (Camb.), 53, 2017
5OHS
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A GH31 FAMILY SULFOQUINOVOSIDASE MUTANT D455N IN COMPLEX WITH PNPSQ
Descriptor:Alpha-glucosidase yihQ, THIOCYANATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Jin, Y., Williams, S.J., Goddard-Borger, E., Davies, G.J.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OHT
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A GH31 FAMILY SULFOQUINOVOSIDASE FROM E. COLI IN COMPLEX WITH AZA-SUGAR INHIBITOR IFGSQ
Descriptor:Sulfoquinovosidase, CALCIUM ION, [(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methanesulfonic acid
Authors:Jin, Y., Williams, S.J., Goddard-Borger, E., Davies, G.J.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OHY
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A GH31 FAMILY SULFOQUINOVOSIDASE IN COMPLEX WITH AZA-SUGAR INHIBITOR IFGSQ
Descriptor:Alpha-glucosidase yihQ, POTASSIUM ION, 1,2-ETHANEDIOL, ...
Authors:Jin, Y., Williams, S.J., Goddard-Borger, E., Davies, G.J.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
3H5V
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CRYSTAL STRUCTURE OF THE GLUR2-ATD
Descriptor:Glutamate receptor 2, N-ACETYL-D-GLUCOSAMINE
Authors:Jin, R., Singh, S.K., Gu, S., Furukawa, H., Sobolevsky, A., Zhou, J., Jin, Y., Gouaux, E.
Deposit date:2009-04-22
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
3H5W
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CRYSTAL STRUCTURE OF THE GLUR2-ATD IN SPACE GROUP P212121 WITHOUT SOLVENT
Descriptor:Glutamate receptor 2
Authors:Jin, R., Singh, S.K., Gu, S., Furukawa, H., Sobolevsky, A., Zhou, J., Jin, Y., Gouaux, E.
Deposit date:2009-04-22
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.686 Å)
Cite:Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
1O5T
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CRYSTAL STRUCTURE OF THE AMINOACYLATION CATALYTIC FRAGMENT OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
Descriptor:Tryptophanyl-tRNA synthetase
Authors:Yu, Y., Liu, Y., Shen, N., Xu, X., Jia, J., Jin, Y., Arnold, E., Ding, J.
Deposit date:2003-10-05
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment
J.BIOL.CHEM., 279, 2004
5IWX
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CRYSTAL STRUCTURE OF 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BACILLUS SUBTITIS
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MAGNESIUM ION
Authors:Liu, Z.C., Jin, Y., Wang, G.G.
Deposit date:2016-03-23
Release date:2017-03-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly among IspD/IspE/IspF enzymes in the MEP pathway.
Biosci. Rep., 2018
5IWY
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CRYSTAL STRUCTURE OF 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BACILLUS SUBTITIS COMPLEXED WITH CMP AND MG2+
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MAGNESIUM ION, CYTIDINE-5'-MONOPHOSPHATE
Authors:Liu, Z.C., Jin, Y., Wang, G.G.
Deposit date:2016-03-23
Release date:2017-03-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly among IspD/IspE/IspF enzymes in the MEP pathway.
Biosci. Rep., 2018
1AKH
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MAT A1/ALPHA2/DNA TERNARY COMPLEX
Descriptor:DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ...
Authors:Li, T., Jin, Y., Vershon, A.K., Wolberger, C.
Deposit date:1997-05-19
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998