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4EW7
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THE CRYSTAL STRUCTURE OF CONJUGATIVE TRANSFER PAS_LIKE DOMAIN FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM
Descriptor:Conjugative transfer: regulation, SUCCINIC ACID, ACETIC ACID, ...
Authors:Wu, R., Jedrzejczak, R.P., Brown, R.N., Cort, J.R., Heffron, F., Nakayasu, E.S., Adkins, J.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
Deposit date:2012-04-26
Release date:2012-09-12
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The crystal structure of conjugative transfer PAS_like domain from Salmonella enterica subsp. enterica serovar Typhimurium
To be Published
6XKF
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THE CRYSTAL STRUCTURE OF 3CL MAINPRO OF SARS-COV-2 WITH OXIDIZED CYS145 (SULFENIC ACID CYSTEINE).
Descriptor:3C-like proteinase, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Coates, L., Kovalevskyi, A.Y., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-06-26
Release date:2020-07-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of 3CL MainPro of SARS-CoV-2 with oxidized Cys145 (Sulfenic acid cysteine).
To Be Published
6XKH
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THE 1.28A CRYSTAL STRUCTURE OF 3CL MAINPRO OF SARS-COV-2 WITH OXIDIZED C145 (SULFINIC ACID CYSTEINE)
Descriptor:3C-like proteinase, 1,2-ETHANEDIOL, FORMIC ACID, ...
Authors:Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Coates, L., Kovalevsky, A., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-06-26
Release date:2020-07-08
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:THE 1.28A CRYSTAL STRUCTURE OF 3CL MAINPRO OF SARS-COV-2 WITH OXIDIZED C145 (sulfinic acid cysteine)
To Be Published
6XOA
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THE CRYSTAL STRUCTURE OF 3CL MAINPRO OF SARS-COV-2 WITH C145S MUTATION
Descriptor:3C-like proteinase, 1,2-ETHANEDIOL
Authors:Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-06
Release date:2020-07-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of 3CL MainPro of SARS-CoV-2 with C145S mutation
To Be Published
7JFQ
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THE CRYSTAL STRUCTURE OF 3CL MAINPRO OF SARS-COV-2 WITH DE-OXIDIZED C145
Descriptor:3C-like proteinase, 1,2-ETHANEDIOL, FORMIC ACID
Authors:Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-17
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The crystal structure of 3CL MainPro of SARS-CoV-2 with de-oxidized C145
To Be Published
5KIN
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE ALPHA BETA COMPLEX FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, GLYCEROL
Authors:Chang, C., Michalska, K., Bigelow, L., Jedrzejczak, R., ANDERSON, W.F., JOACHIMIAK, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-06-16
Release date:2016-07-06
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Conservation of the structure and function of bacterial tryptophan synthases.
Iucrj, 6, 2019
5KZM
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE ALPHA-BETA CHAIN COMPLEX FROM FRANCISELLA TULARENSIS
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, ACETATE ION, ...
Authors:Chang, C., Michalska, K., Joachimiak, G., Jedrzejczak, R., ANDERSON, W.F., JOACHIMIAK, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-07-25
Release date:2016-08-10
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Conservation of the structure and function of bacterial tryptophan synthases.
Iucrj, 6, 2019
5TCF
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE FROM M. TUBERCULOSIS - LIGAND-FREE FORM
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, MALONATE ION, ...
Authors:Michalska, K., Maltseva, N., Jedrzejczak, R., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-09-15
Release date:2017-05-31
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat. Chem. Biol., 13, 2017
5TCG
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE FROM M. TUBERCULOSIS - AMINOACRYLATE-BOUND FORM
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, MALONATE ION, ...
Authors:Michalska, K., Maltseva, N., Jedrzejczak, R., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-09-15
Release date:2017-05-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat. Chem. Biol., 13, 2017
5TCH
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE FROM M. TUBERCULOSIS - LIGAND-FREE FORM, TRPA-G66V MUTANT
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, MALONATE ION, ...
Authors:Michalska, K., Maltseva, N., Jedrzejczak, R., Wellington, S., Nag, P.P., Fisher, S.L., Schreiber, S.L., Hung, D.T., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-09-15
Release date:2017-05-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat. Chem. Biol., 13, 2017
5TCI
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE FROM M. TUBERCULOSIS - BRD4592-BOUND FORM
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, MALONATE ION, ...
Authors:Michalska, K., Maltseva, N., Jedrzejczak, R., Wellington, S., Nag, P.P., Fisher, S.L., Schreiber, S.L., Hung, D.T., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-09-15
Release date:2017-05-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat. Chem. Biol., 13, 2017
5TCJ
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE FROM M. TUBERCULOSIS - AMINOACRYLATE AND BRD4592-BOUND FORM
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, MALONATE ION, ...
Authors:Michalska, K., Maltseva, N., Jedrzejczak, R., Wellington, S., Nag, P.P., Fisher, S.L., Schreiber, S.L., Hung, D.T., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-09-15
Release date:2017-05-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat. Chem. Biol., 13, 2017
5VES
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THE 2.4A CRYSTAL STRUCTURE OF OMPA DOMAIN OF OMPA FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM STR. 14028S
Descriptor:Outer membrane protein A, SULFATE ION
Authors:Tan, K., Wu, R., Jedrzejczak, R., Adkins, J., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
Deposit date:2017-04-05
Release date:2017-04-19
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
Protein Sci., 26, 2017
6OYF
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THE STRUCTURE OF CONDENSATION AND ADENYLATION DOMAINS OF TEIXOBACTIN-PRODUCING NONRIBOSOMAL PEPTIDE SYNTHETASE TXO1 SERINE MODULE
Descriptor:Txo1, FORMIC ACID, SULFATE ION, ...
Authors:Tan, K., Zhou, M., Jedrzejczak, R., Babnigg, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-14
Release date:2019-05-29
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains.
Curr Res Struct Biol, 2, 2020
6OZV
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THE STRUCTURE OF CONDENSATION AND ADENYLATION DOMAINS OF TEIXOBACTIN-PRODUCING NONRIBOSOMAL PEPTIDE SYNTHETASE TXO1 SERINE MODULE IN COMPLEX WITH AMP
Descriptor:Txo1, ADENOSINE MONOPHOSPHATE, SULFATE ION, ...
Authors:Tan, K., Zhou, M., Jedrzejczak, R., Babnigg, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-16
Release date:2019-05-29
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains.
Curr Res Struct Biol, 2, 2020
6P1J
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THE STRUCTURE OF CONDENSATION AND ADENYLATION DOMAINS OF TEIXOBACTIN-PRODUCING NONRIBOSOMAL PEPTIDE SYNTHETASE TXO2 SERINE MODULE
Descriptor:Txo2, FORMIC ACID, CITRATE ANION, ...
Authors:Tan, K., Zhou, M., Jedrzejczak, R., Babnigg, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-20
Release date:2019-05-29
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains.
Curr Res Struct Biol, 2, 2020
6P3I
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THE STRUCTURE OF CONDENSATION AND ADENYLATION DOMAINS OF TEIXOBACTIN-PRODUCING NONRIBOSOMAL PEPTIDE SYNTHETASE TXO1 SERINE MODULE IN COMPLEX WITH MG
Descriptor:Txo1, MAGNESIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Tan, K., Zhou, M., Jedrzejczak, R., Babnigg, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-23
Release date:2019-06-05
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains.
Curr Res Struct Biol, 2, 2020
6P4U
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THE STRUCTURE OF CONDENSATION AND ADENYLATION DOMAINS OF TEIXOBACTIN-PRODUCING NONRIBOSOMAL PEPTIDE SYNTHETASE TXO1 SERINE MODULE IN COMPLEX WITH MG AND AMP
Descriptor:Txo1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Tan, K., Zhou, M., Jedrzejczak, R., Babnigg, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-28
Release date:2019-06-12
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains.
Curr Res Struct Biol, 2, 2020
3OON
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THE STRUCTURE OF AN OUTER MEMBRANCE PROTEIN FROM BORRELIA BURGDORFERI B31
Descriptor:Outer membrane protein (Tpn50), SULFATE ION
Authors:Fan, Y., Bigelow, L., Feldman, B., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-08-31
Release date:2010-09-22
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
Protein Sci., 26, 2017
4RHA
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STRUCTURE OF THE C-TERMINAL DOMAIN OF OUTER-MEMBRANE PROTEIN OMPA FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM STR. 14028S
Descriptor:Outer membrane protein A, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Cuff, M.E., Skarina, T., Savchenko, A., Edwards, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-10-01
Release date:2014-10-29
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
Protein Sci., 26, 2017
167518
PDB entries from 2020-08-12