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4CP3
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THE STRUCTURE OF BCL6 BTB (POZ) DOMAIN IN COMPLEX WITH THE ANSAMYCIN ANTIBIOTIC RIFABUTIN.
Descriptor:B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
Authors:Evans, S.E., Fairall, L., Goult, B.T., Jamieson, A.G., Ferrigno, P.K., Ford, R., Wagner, S.D., Schwabe, J.W.R.
Deposit date:2014-01-31
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
5ICN
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HDAC1:MTA1 IN COMPLEX WITH INOSITOL-6-PHOSPHATE AND A NOVEL PEPTIDE INHIBITOR BASED ON HISTONE H4
Descriptor:Metastasis-associated protein MTA1, Histone deacetylase 1, GLY-ALA-6A0-ARG-HIS, ...
Authors:Millard, C.J., Robertson, N.S., Watson, P.J., Jameson, A.G., Schwabe, J.W.R.
Deposit date:2016-02-23
Release date:2016-05-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
5LXM
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CRYSTAL STRUCTURE OF AURORA-A BOUND TO A HYDROCARBON-STAPLED PROTEOMIMETIC OF TPX2
Descriptor:Aurora kinase A, Targeting protein for Xklp2, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:McIntyre, P.J., Bayliss, R.
Deposit date:2016-09-22
Release date:2016-11-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix.
ACS Chem. Biol., 11, 2016