Author results

1AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
1M3V
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FLIN4: FUSION OF THE LIM BINDING DOMAIN OF LDB1 AND THE N-TERMINAL LIM DOMAIN OF LMO4
Descriptor:fusion of the LIM interacting domain of ldb1 and the N-terminal LIM domain of LMO4, ZINC ION
Authors:Deane, J.E., Mackay, J.P., Kwan, A.H.Y., Sum, E.Y., Visvader, J.E., Matthews, J.M.
Deposit date:2002-06-30
Release date:2003-05-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
EMBO J., 22, 2003
2AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
2CK3
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AZIDE INHIBITED BOVINE F1-ATPASE
Descriptor:ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT BETA, ...
Authors:Bowler, M.W., Montgomery, M.G., Leslie, A.G.W., Walker, J.E.
Deposit date:2006-04-10
Release date:2006-05-08
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:How Azide Inhibits ATP Hydrolysis by the F-Atpases.
Proc.Natl.Acad.Sci.USA, 103, 2006
3AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
4AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
5AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
6AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
7AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Stevens, R.C., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
8AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Stevens, R.C., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
1J2O
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STRUCTURE OF FLIN2, A COMPLEX CONTAINING THE N-TERMINAL LIM DOMAIN OF LMO2 AND LDB1-LID
Descriptor:Fusion of Rhombotin-2 and LIM domain-binding protein 1, ZINC ION
Authors:Deane, J.E., Mackay, J.P., Kwan, A.H., Sum, E.Y., Visvader, J.E., Matthews, J.M.
Deposit date:2003-01-08
Release date:2003-05-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
EMBO J., 22, 2003
1RUT
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COMPLEX OF LMO4 LIM DOMAINS 1 AND 2 WITH THE LDB1 LID DOMAIN
Descriptor:Fusion protein of Lmo4 protein and LIM domain-binding protein 1, ZINC ION
Authors:Deane, J.E., Ryan, D.P., Maher, M.J., Kwan, A.H.Y., Bacca, M., Mackay, J.P., Guss, J.M., Visvader, J.E., Matthews, J.M.
Deposit date:2003-12-11
Release date:2004-10-12
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex
Embo J., 23, 2004
1W0J
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BERYLLIUM FLUORIDE INHIBITED BOVINE F1-ATPASE
Descriptor:ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, MITOCHONDRIAL PRECURSOR, ATP SYNTHASE BETA CHAIN, ...
Authors:Kagawa, R., Montgomery, M.G., Braig, K., Walker, J.E., Leslie, A.G.W.
Deposit date:2004-06-08
Release date:2004-07-08
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of Bovine F1-ATPase Inhibited by Adp and Beryllium Fluoride
Embo J., 23, 2004
1W0K
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ADP INHIBITED BOVINE F1-ATPASE
Descriptor:ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, MITOCHONDRIAL PRECURSOR, ATP SYNTHASE BETA CHAIN, ...
Authors:Kagawa, R., Montgomery, M.G., Braig, K., Walker, J.E., Leslie, A.G.W.
Deposit date:2004-06-08
Release date:2004-07-08
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Structure of Bovine F1-ATPase Inhibited by Adp and Beryllium Fluoride
Embo J., 23, 2004
2HLD
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CRYSTAL STRUCTURE OF YEAST MITOCHONDRIAL F1-ATPASE
Descriptor:ATP synthase alpha chain, mitochondrial, ATP synthase beta chain, ...
Authors:Kabaleeswaran, V., Puri, N., Walker, J.E., Leslie, A.G., Mueller, D.M.
Deposit date:2006-07-06
Release date:2006-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Novel features of the rotary catalytic mechanism revealed in the structure of yeast F(1) ATPase.
Embo J., 25, 2006
1BIO
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HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR
Descriptor:COMPLEMENT FACTOR D, ISATOIC ANHYDRIDE, GLYCEROL
Authors:Jing, H., Babu, Y.S., Moore, D., Kilpatrick, J.M., Liu, X.-Y., Volanakis, J.E., Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
1C4T
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CATALYTIC DOMAIN FROM TRIMERIC DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
Descriptor:PROTEIN (DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE), SULFATE ION
Authors:Knapp, J.E., Carroll, D., Lawson, J.E., Ernst, S.R., Reed, L.J., Hackert, M.L.
Deposit date:1999-09-22
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase.
Protein Sci., 9, 2000
1H8E
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(ADP.ALF4)2(ADP.SO4) BOVINE F1-ATPASE (ALL THREE CATALYTIC SITES OCCUPIED)
Descriptor:BOVINE MITOCHONDRIAL F1-ATPASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Menz, R.I., Walker, J.E., Leslie, A.G.W.
Deposit date:2001-02-02
Release date:2001-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Bovine Mitochondrial F1-ATPase with Nucleotide Bound to All Three Catalytic Sites: Implications for the Mechanism of Rotary Catalysis
Cell(Cambridge,Mass.), 106, 2001
1DIA
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HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY249543
Descriptor:METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [[[2-AMINO-5,6,7,8-TETRAHYDRO-4-HYDROXY-PYRIDO[2,3-D]PYRIMIDIN-6-YL]-ETHYL]-PHENYL]-CARBONYL-GLUTAMIC ACID
Authors:Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.
Deposit date:1999-11-29
Release date:2000-07-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
1DIB
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HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY345899
Descriptor:METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-(7-AMINO-9-HYDROXY-1-OXO-3,3A,4,5-TETRAHYDRO-2,5,6,8,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALEN-2-YL)-PHENYLCARBONYL-GLUTAMIC ACID
Authors:Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.
Deposit date:1999-11-29
Release date:2000-07-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
1DIG
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HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY374571
Descriptor:METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [[N'-(2,5-DIAMINO-6-HYDROXY-PYRIMIDIN-4-YL)-UREAYL]-PHEN-4-YL]-CARBONYL-GLUTAMIC ACID, ...
Authors:Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.
Deposit date:1999-11-29
Release date:2000-07-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
1DST
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MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY
Descriptor:FACTOR D
Authors:Narayana, S.V.L., Volanakis, J.E.
Deposit date:1995-09-13
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.
J.Biol.Chem., 270, 1995
1E79
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BOVINE F1-ATPASE INHIBITED BY DCCD (DICYCLOHEXYLCARBODIIMIDE)
Descriptor:ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, ATP SYNTHASE BETA CHAIN, ATP SYNTHASE GAMMA CHAIN, ...
Authors:Gibbons, C., Montgomery, M.G., Leslie, A.G.W., Walker, J.E.
Deposit date:2000-08-25
Release date:2000-11-03
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the Central Stalk in Bovine F(1)-ATPase at 2.4 A Resolution.
Nat.Struct.Biol., 7, 2000
1EFR
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BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE PEPTIDE ANTIBIOTIC EFRAPEPTIN
Descriptor:BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT ALPHA, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT BETA, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT GAMMA, ...
Authors:Abrahams, J.P., Buchanan, S.K., Van Raaij, M.J., Fearnley, I.M., Leslie, A.G.W., Walker, J.E.
Deposit date:1996-05-24
Release date:1997-02-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Structure of Bovine F1-ATPase Complexed with the Peptide Antibiotic Efrapeptin.
Proc.Natl.Acad.Sci.USA, 93, 1996
1FDP
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PROENZYME OF HUMAN COMPLEMENT FACTOR D, RECOMBINANT PROFACTOR D
Descriptor:PROENZYME OF COMPLEMENT FACTOR D
Authors:Jing, H., Macon, K.J., Moore, D., Delucas, L.J., Volanakis, J.E., Narayana, S.V.L.
Deposit date:1998-12-03
Release date:1999-12-03
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D.
Embo J., 18, 1999