Author results

2F6I
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CRYSTAL STRUCTURE OF THE CLPP PROTEASE CATALYTIC DOMAIN FROM PLASMODIUM FALCIPARUM
分子名称:ATP-dependent CLP protease, putative
著者Mulichak, A., Loppnau, P., Bray, J., Amani, M., Vedadi, M., Wasney, G., Finerty, P., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
登録日2005-11-29
公開日2005-12-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
2Q58
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CRYPTOSPORIDIUM PARVUM PUTATIVE POLYPRENYL PYROPHOSPHATE SYNTHASE (CGD4_2550) IN COMPLEX WITH ZOLEDRONATE
分子名称:Farnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID
著者Chruszcz, M., Artz, J., Zheng, H., Dong, A., Dunford, J., Lew, J., Zhao, Y., Kozieradski, I., Kavanaugh, K.L., Opperman, U., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Bochkarev, A., Hui, R., Minor, W., Structural Genomics Consortium (SGC)
登録日2007-05-31
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis
Chem.Biol., 15, 2008
6NIM
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TRYPANOSOMA CRUZI - BDF2, TCCLB.506553.20, SOLVED WITH BROMOSPORINE
分子名称:Bromodomain factor 2 protein, SULFATE ION, UNKNOWN ATOM OR ION, ...
著者Lin, Y.H., Dong, A., Tempel, W., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Vedadi, M., Harding, R., Structural Genomics Consortium (SGC)
登録日2018-12-29
公開日2019-01-30
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Trypanosoma cruzi - BDF2, TcCLB.506553.20, solved with bromosporine
to be published
2FBN
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PLASMODIUM FALCIPARUM PUTATIVE FK506-BINDING PROTEIN PFL2275C, C-TERMINAL TPR-CONTAINING DOMAIN
分子名称:70 kDa peptidylprolyl isomerase, putative
著者Dong, A., Lew, J., Koeieradzki, I., Sundararajan, E., Melone, M., Wasney, G., Zhao, Y., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
登録日2005-12-09
公開日2006-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C-terminal pentapeptide.
Protein Sci., 18, 2009
3EOE
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CRYSTAL STRUCTURE OF PYRUVATE KINASE FROM TOXOPLASMA GONDII, 55.M00007
分子名称:Pyruvate kinase, GLYCEROL
著者Wernimont, A.K., Lew, J., Kozieradzki, I., Wasney, G., Hassani, A., Vedadi, M., Cossar, D., Schapiro, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Pizarro, J., Structural Genomics Consortium (SGC)
登録日2008-09-26
公開日2008-10-14
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The crystal structure of Toxoplasma gondii pyruvate kinase 1.
Plos One, 5, 2010
3GG8
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CRYSTAL STRUCTURE OF THE TOXOPLASMA GONDII PYRUVATE KINASE N TERMINAL TRUNCATED
分子名称:Pyruvate kinase, SULFATE ION, GLYCEROL
著者Wernimont, A.K., Lew, J., Allali-Hassani, A., Vedadi, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hills, T., Schapira, M., Hui, R., Pizarro, J.C., Structural Genomics Consortium (SGC)
登録日2009-02-27
公開日2009-05-26
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献The crystal structure of Toxoplasma gondii pyruvate kinase 1.
Plos One, 5, 2010
3H5Z
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA
分子名称:Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, 1,2-ETHANEDIOL, ...
著者Qiu, W., Hutchinson, A., Lin, Y.-H., Wernimont, A., Mackenzie, F., Ravichandran, M., Cossar, D., Zhao, Y., Schapira, M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Ferguson, M.A.J., Fairlamb, A.H., Hui, R., Structural Genomics Consortium (SGC)
登録日2009-04-22
公開日2009-05-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Nature, 464, 2010
3KHD
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CRYSTAL STRUCTURE OF PFF1300W.
分子名称:Pyruvate kinase
著者Wernimont, A.K., Hutchinson, A., Hassanali, A., Mackenzie, F., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Pizarro, J.C., Bakszt, R., Hills, T., Structural Genomics Consortium (SGC)
登録日2009-10-30
公開日2010-01-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of PFF1300w.
To be Published
6CJI
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CANDIDA ALBICANS HSP90 NUCLEOTIDE BINDING DOMAIN
分子名称:Heat shock protein 90 homolog, 1,2-ETHANEDIOL
著者Hutchinson, A., Loppnau, P., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Hui, R., STRUCTURAL GENOMICS CONSORTIUM, S.G.C., Pizarro, J.C., Structural Genomics Consortium (SGC)
登録日2018-02-26
公開日2019-01-30
最終更新日2019-02-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
6CJJ
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CANDIDA ALBICANS HSP90 NUCLEOTIDE BINDING DOMAIN IN COMPLEX WITH ADP
分子名称:Heat shock protein 90 homolog, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hutchinson, A., Loppnau, P., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Hui, R., STRUCTURAL GENOMICS CONSORTIUM, S.G.C., Pizarro, J.C., Structural Genomics Consortium (SGC)
登録日2018-02-26
公開日2019-01-30
最終更新日2019-02-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
1TXJ
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CRYSTAL STRUCTURE OF TRANSLATIONALLY CONTROLLED TUMOUR-ASSOCIATED PROTEIN (TCTP) FROM PLASMODIUM KNOWLESI
分子名称:translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi, PKN_PFE0545c
著者Walker, J.R., Vedadi, M., Sharma, S., Houston, S., Lew, J., Amani, M., Wasney, G., Skarina, T., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Structural Genomics Consortium (SGC)
登録日2004-07-05
公開日2004-07-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1XCC
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1-CYS PEROXIDOXIN FROM PLASMODIUM YOELLI
分子名称:1-Cys peroxiredoxin
著者Vedadi, M., Sharma, S., Houston, S., Lew, J., Wasney, G., Amani, M., Xu, X., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Bochkarev, A., Structural Genomics Consortium (SGC)
登録日2004-09-01
公開日2004-11-09
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Y6Z
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MIDDLE DOMAIN OF PLASMODIUM FALCIPARUM PUTATIVE HEAT SHOCK PROTEIN PF14_0417
分子名称:heat shock protein, putative
著者Lunin, V.V., Botchkareva, E., Loppnau, P., Amani, M., Bray, J., Vedadi, M., Edwards, A., Arrowsmith, C., Sundstrom, M., Bochkarev, A., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
登録日2004-12-07
公開日2005-02-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z6G
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CRYSTAL STRUCTURE OF GUANYLATE KINASE FROM PLASMODIUM FALCIPARUM
分子名称:guanylate kinase, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Mulichak, A.M., Lew, J., Artz, J., Choe, J., Walker, J.R., Zhao, Y., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Gao, M., Structural Genomics Consortium (SGC)
登録日2005-03-22
公開日2005-04-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z7D
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ORNITHINE AMINOTRANSFERASE PY00104 FROM PLASMODIUM YOELII
分子名称:ornithine aminotransferase
著者Walker, J.R., Alam, Z., Amani, M., Lew, J., Wasney, G., Boulanger, K., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
登録日2005-03-24
公開日2005-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z81
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CRYSTAL STRUCTURE OF CYCLOPHILIN FROM PLASMODIUM YOELII.
分子名称:cyclophilin
著者Mulichak, A., Alam, Z., Amani, M., Lew, J., Wasney, G., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
登録日2005-03-29
公開日2005-04-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1ZO2
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STRUCTURE OF NUCLEAR TRANSPORT FACTOR 2 (NTF2) FROM CRYPTOSPORIDIUM PARVUM
分子名称:nuclear transport factor 2
著者Choe, J., Artz, J.D., Gao, M., Lew, J., Zhao, Y., Arrowsmith, C., Edwards, A., Sundstrom, M., Bochkarev, A., Hui, R., Structural Genomics Consortium (SGC)
登録日2005-05-12
公開日2005-05-31
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2A22
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STRUCTURE OF VACUOLAR PROTEIN SORTING 29 FROM CRYPTOSPORIDIUM PARVUM
分子名称:vacuolar protein sorting 29
著者Brokx, S., Zhao, Y., Alam, Z., Lew, J., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Walker, J.R., Structural Genomics Consortium (SGC)
登録日2005-06-21
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2A4A
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DEOXYRIBOSE-PHOSPHATE ALDOLASE FROM P. YOELII
分子名称:deoxyribose-phosphate aldolase
著者Walker, J.R., Amani, M., Lew, J., Wiegelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
登録日2005-06-28
公開日2005-09-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AIF
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CRYSTAL STRUCTURE OF HIGH MOBILITY LIKE PROTEIN, NHP2, PUTATIVE FROM CRYPTOSPORIDIUM PARVUM
分子名称:ribosomal protein L7A
著者Dong, A., Zhao, Y., Lew, J., Alam, Z., Melone, M., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Hui, R., Bochkarev, A., Artz, J., Structural Genomics Consortium (SGC)
登録日2005-07-29
公開日2005-08-09
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AMX
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CRYSTAL STRUCTURE OF PLASMODIUM YOELII ADENOSINE DEAMINASE (PY02076)
分子名称:adenosine deaminase, COBALT (II) ION, UNKNOWN ATOM OR ION
著者Dong, A., Vedadi, M., Wasney, G., Zhao, Y., Lew, J., Alam, Z., Melone, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
登録日2005-08-10
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AQW
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STRUCTURE OF PUTATIVE OROTIDINE-MONOPHOSPHATE-DECARBOXYLASE FROM PLASMODIUM YOELII (PY01515)
分子名称:putative orotidine-monophosphate-decarboxylase, IODIDE ION, SULFATE ION
著者Dong, A., Vedadi, M., Wasney, G., Zhao, Y., Lew, J., Alam, Z., Melone, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
登録日2005-08-18
公開日2005-08-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AV4
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CRYSTAL STRUCTURE OF PLASMODIUM YOELII THIOREDOXIN-LIKE PROTEIN 4A (DIM1)
分子名称:Thioredoxin-like protein 4A (DIM1), CHLORIDE ION
著者Dong, A., Zhao, Y., Lew, J., Alam, Z., Melone, M., Wasney, G., Vedadi, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J., Structural Genomics Consortium (SGC)
登録日2005-08-29
公開日2005-09-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AWP
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CRYSTAL STRUCTURE OF PLASMODIUM KNOWLESI STRUCTURE OF IRON SUPER-OXIDE DISMUTASE
分子名称:Iron Super-Oxide Dismutase, CHLORIDE ION, UNKNOWN ATOM OR ION
著者Dong, A., Zhao, Y., Lew, J., Alam, Z., Melone, M., Wasney, G., Vedadi, M., Koeieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
登録日2005-09-01
公開日2005-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2AYV
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CRYSTAL STRUCTURE OF A PUTATIVE UBIQUITIN-CONJUGATING ENZYME E2 FROM TOXOPLASMA GONDII
分子名称:ubiquitin-conjugating enzyme E2, UNKNOWN ATOM OR ION
著者Tempel, W., Dong, A., Zhao, Y., Lew, J., Alam, Z., Melone, M., Wasney, G., Kozieradzki, I., Vedadi, M., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
登録日2005-09-08
公開日2005-09-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007