3KHE

Crystal structure of the calcium-loaded calmodulin-like domain of the CDPK, 541.m00134 from toxoplasma gondii

Summary for 3KHE

Entry DOI	10.2210/pdb3khe/pdb
Descriptor	Calmodulin-like domain protein kinase isoform 3, CALCIUM ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	calcium dependent kinase, structural genomics, structural genomics consortium, sgc, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, metal binding protein
Biological source	Toxoplasma gondii
Total number of polymer chains	2
Total formula weight	44354.71
Authors	Wernimont, A.K.,Hutchinson, A.,Artz, J.D.,Mackenzie, F.,Cossar, D.,Kozieradzki, I.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Hui, R.,Qiu, W.,Amani, M.,Structural Genomics Consortium (SGC) (deposition date: 2009-10-30, release date: 2010-01-19, Last modification date: 2024-02-21)
Primary citation	Wernimont, A.K.,Amani, M.,Qiu, W.,Pizarro, J.C.,Artz, J.D.,Lin, Y.H.,Lew, J.,Hutchinson, A.,Hui, R. Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins, 79:803-820, 2011 Cited by PubMed: 21287613 DOI: 10.1002/prot.22919 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation