Author results

1BVK
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HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME
Descriptor:HULYS11, LYSOZYME
Authors:Holmes, M.A., Buss, T.N., Foote, J.
Deposit date:1998-09-16
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational correction mechanisms aiding antigen recognition by a humanized antibody.
J.Exp.Med., 187, 1998
1HMD
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THE STRUCTURE OF DEOXY AND OXY HEMERYTHRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:HEMERYTHRIN, ACETYL GROUP, MU-OXO-DIIRON
Authors:Holmes, M.A., Letrong, I., Turley, S., Sieker, L.C., Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of deoxy and oxy hemerythrin at 2.0 A resolution.
J.Mol.Biol., 218, 1991
1HMO
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THE STRUCTURE OF DEOXY AND OXY HEMERYTHRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:HEMERYTHRIN, ACETYL GROUP, MU-OXO-DIIRON, ...
Authors:Holmes, M.A., Letrong, I., Turley, S., Sieker, L.C., Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of deoxy and oxy hemerythrin at 2.0 A resolution.
J.Mol.Biol., 218, 1991
2HMQ
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THE STRUCTURES OF MET AND AZIDOMET HEMERYTHRIN AT 1.66 ANGSTROMS RESOLUTION
Descriptor:HEMERYTHRIN, ACETATE ION, MU-OXO-DIIRON
Authors:Holmes, M.A., Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of met and azidomet hemerythrin at 1.66 A resolution.
J.Mol.Biol., 220, 1991
2HMZ
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THE STRUCTURES OF MET AND AZIDOMET HEMERYTHRIN AT 1.66 ANGSTROMS RESOLUTION
Descriptor:HEMERYTHRIN, ACETATE ION, MONOAZIDO-MU-OXO-DIIRON
Authors:Holmes, M.A., Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of met and azidomet hemerythrin at 1.66 A resolution.
J.Mol.Biol., 220, 1991
1BVL
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HUMANIZED ANTI-LYSOZYME FV
Descriptor:HULYS11
Authors:Holmes, M.A., Foote, J.
Deposit date:1998-09-16
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural consequences of humanizing an antibody.
J.Immunol., 158, 1997
1JE6
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STRUCTURE OF THE MHC CLASS I HOMOLOG MICB
Descriptor:MHC class I chain-related protein, SULFATE ION
Authors:Holmes, M.A., Li, P., Strong, R.K.
Deposit date:2001-06-15
Release date:2002-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of allelic diversity of the MHC class I homolog MIC-B, a stress-inducible ligand for the activating immunoreceptor NKG2D.
J.Immunol., 169, 2002
1X71
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH TRENCAM-3,2-HOPO, A CEPABACTIN ANALOGUE
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, 2,3-DIHYDROXYBENZAMIDE
Authors:Holmes, M.A., Paulsene, W., Jide, X., Ratledge, C., Strong, R.K.
Deposit date:2004-08-12
Release date:2005-01-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1X89
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH CARBOXYMYCOBACTIN S
Descriptor:Neutrophil gelatinase-associated lipocalin, CARBOXYMYCOBACTIN S
Authors:Holmes, M.A., Paulsene, W., Jide, X., Ratledge, C., Strong, R.K.
Deposit date:2004-08-17
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1X8U
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH CARBOXYMYCOBACTIN T
Descriptor:Neutrophil gelatinase-associated lipocalin, CARBOXYMYCOBACTIN T
Authors:Holmes, M.A., Paulsene, W., Jide, X., Ratledge, C., Strong, R.K.
Deposit date:2004-08-18
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1ZSO
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HYPOTHETICAL PROTEIN FROM PLASMODIUM FALCIPARUM
Descriptor:hypothetical protein
Authors:Holmes, M.A., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-05-24
Release date:2005-06-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
2A03
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SUPEROXIDE DISMUTASE PROTEIN FROM PLASMODIUM BERGHEI
Descriptor:Fe-superoxide dismutase homolog, MANGANESE (II) ION, ZINC ION
Authors:Holmes, M.A., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-15
Release date:2005-06-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Hypothetical protein from plasmodium berghei
To be published
2B4W
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HYPOTHETICAL PROTEIN FROM LEISHMANIA MAJOR
Descriptor:hypothetical protein, conserved
Authors:Holmes, M.A., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-26
Release date:2005-10-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Hypothetical protein from leishmania major
TO BE PUBLISHED
2F8M
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RIBOSE 5-PHOSPHATE ISOMERASE FROM PLASMODIUM FALCIPARUM
Descriptor:ribose 5-phosphate isomerase, PHOSPHATE ION
Authors:Holmes, M.A., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-12-02
Release date:2005-12-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
7TLN
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STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR
Descriptor:THERMOLYSIN, CALCIUM ION, ZINC ION, ...
Authors:Matthews, B.W., Holmes, M.A., Tronrud, D.E.
Deposit date:1983-01-27
Release date:1983-03-09
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor.
Biochemistry, 22, 1983
4TLN
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BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
Descriptor:THERMOLYSIN, CALCIUM ION, ZINC ION, ...
Authors:Matthews, B.W., Holmes, M.A.
Deposit date:1982-02-08
Release date:1982-05-26
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
5TLN
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BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
Descriptor:THERMOLYSIN, CALCIUM ION, ZINC ION, ...
Authors:Matthews, B.W., Holmes, M.A.
Deposit date:1982-02-08
Release date:1982-05-26
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
1KPR
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Holmes, M.A., Strong, R.K.
Deposit date:2002-01-02
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
1KTL
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Holmes, M.A., Strong, R.K.
Deposit date:2002-01-16
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
3H3P
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10 FV COMPLEX
Descriptor:Fv 4E10 heavy chain, Fv 4E10 light chain, 4E10_S0_1TJLC_004_N, ...
Authors:Holmes, M.A.
Deposit date:2009-04-16
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity
J.Virol., 84, 2010
3LEF
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10_S0_1Z6NA_001
Descriptor:Uncharacterized protein 4E10_S0_1Z6NA_001 (T18), 1,2-ETHANEDIOL
Authors:Holmes, M.A.
Deposit date:2010-01-14
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LF6
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10_1XIZA_S0_001_N
Descriptor:Putative phosphotransferase system, PHOSPHATE ION
Authors:Holmes, M.A.
Deposit date:2010-01-15
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LF9
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10_D0_1IS1A_001_C
Descriptor:4E10_D0_1IS1A_001_C (T161)
Authors:Holmes, M.A.
Deposit date:2010-01-16
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LG7
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10_S0_1EZ3A_002_C
Descriptor:4E10_S0_1EZ3A_002_C (T246), SULFATE ION
Authors:Holmes, M.A.
Deposit date:2010-01-19
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LH2
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10_1VI7A_S0_002_N 4E10 FV COMPLEX
Descriptor:4E10_1VI7A_S0_002_N (T88), Fv 4E10 heavy chain, Fv 4E10 light chain
Authors:Holmes, M.A.
Deposit date:2010-01-21
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
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