1KK8
| SCALLOP MYOSIN (S1-ADP-BeFx) IN THE ACTIN-DETACHED CONFORMATION | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... | Authors: | Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | Deposit date: | 2001-12-06 | Release date: | 2002-10-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1L2O
| SCALLOP MYOSIN S1-ADP-p-PDM IN THE ACTIN-DETACHED CONFORMATION | Descriptor: | 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | Deposit date: | 2002-02-22 | Release date: | 2002-10-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
6ZYB
| |
6ZXZ
| Sarcin-Ricin Loop RNA from Ecoli with a A2670-2'-OCF3 modification | Descriptor: | POTASSIUM ION, SODIUM ION, Sarcin-Ricin Loop RNA from Ecoli with a A2670-2'-OCF3 modification | Authors: | Ennifar, E. | Deposit date: | 2020-07-30 | Release date: | 2020-12-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | 2'- O -Trifluoromethylated RNA - a powerful modification for RNA chemistry and NMR spectroscopy. Chem Sci, 11, 2020
|
|
3DYJ
| |
7MU6
| Ask1 bound to compound 28 | Descriptor: | 2-methoxy-N-(6-{4-[(2S)-1,1,1-trifluoropropan-2-yl]-4H-1,2,4-triazol-3-yl}pyridin-2-yl)pyridine-3-carboxamide, Mitogen-activated protein kinase kinase kinase 5 | Authors: | Chodaparambil, J.V, Marcotte, D.J. | Deposit date: | 2021-05-14 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.165 Å) | Cite: | Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo. J.Med.Chem., 64, 2021
|
|
7L3R
| |
6XUR
| RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | Deposit date: | 2020-01-21 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL). Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6XUS
| RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base, SODIUM ION | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | Deposit date: | 2020-01-21 | Release date: | 2021-02-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL). Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
5ACY
| N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1-(2R,4S)-2-methyl-4-(phenylamino)-6-4-(piperidin-1-ylmethyl)phenyl-1,2,3,4- tetrahydroquinolin-1-yl-ethan-1-one | Descriptor: | 1,2-ETHANEDIOL, 1-[(2S,4R)-2-methyl-4-(phenylamino)-6-[4-(piperidin-1-ylmethyl)phenyl]-3,4-dihydroquinolin-1(2H)-yl]ethanone, BROMODOMAIN-CONTAINING PROTEIN 4 | Authors: | Chung, C. | Deposit date: | 2015-08-18 | Release date: | 2015-10-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Autism-Like Syndrome is Induced by Pharmacological Suppression of Bet Proteins in Young Mice. J.Exp.Med., 212, 2015
|
|