4HU3 | | CRYSTAL STRUCTURE OF EAL DOMAIN OF THE E. COLI DOSP - MONOMERIC FORM | | Descriptor: | Oxygen sensor protein DosP | | Authors: | Tarnawski, M., Barends, T.R.M., Hartmann, E., Schlichting, I. | | Deposit date: | 2012-11-02 | | Release date: | 2013-05-29 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (3.301 Å) | | Cite: | Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4HU4 | | CRYSTAL STRUCTURE OF EAL DOMAIN OF THE E. COLI DOSP - DIMERIC FORM | | Descriptor: | Oxygen sensor protein DosP | | Authors: | Tarnawski, M., Barends, T.R.M., Hartmann, E., Schlichting, I. | | Deposit date: | 2012-11-02 | | Release date: | 2013-05-29 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
1RD5 | | CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE ALPHA CHAIN HOMOLOG BX1: A MEMBER OF THE CHEMICAL PLANT DEFENSE SYSTEM | | Descriptor: | Tryptophan synthase alpha chain, chloroplast, MALONIC ACID | | Authors: | Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M.F., Schlichting, I. | | Deposit date: | 2003-11-05 | | Release date: | 2004-12-28 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
|
|
1N9L | | CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN THE DARK STATE. | | Descriptor: | putative blue light receptor, SULFATE ION, FLAVIN MONONUCLEOTIDE | | Authors: | Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P. | | Deposit date: | 2002-11-25 | | Release date: | 2003-06-17 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
|
|
1N9N | | CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN ILLUMINATED STATE. DATA SET OF A SINGLE CRYSTAL. | | Descriptor: | putative blue light receptor, FLAVIN MONONUCLEOTIDE | | Authors: | Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P. | | Deposit date: | 2002-11-25 | | Release date: | 2003-06-17 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
|
|
1N9O | | CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN ILLUMINATED STATE. COMPOSITE DATA SET. | | Descriptor: | putative blue light receptor, SULFATE ION, FLAVIN MONONUCLEOTIDE | | Authors: | Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P. | | Deposit date: | 2002-11-25 | | Release date: | 2003-06-17 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
|
|
1QW4 | | CRYSTAL STRUCTURE OF MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH N-OMEGA-PROPYL-L-ARGININE. | | Descriptor: | Nitric oxide synthase, inducible, ZINC ION, ... | | Authors: | Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I. | | Deposit date: | 2003-08-31 | | Release date: | 2003-12-09 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
|
|
1QW5 | | MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH W1400 INHIBITOR. | | Descriptor: | Nitric oxide synthase, inducible, ZINC ION, ... | | Authors: | Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I. | | Deposit date: | 2003-08-31 | | Release date: | 2003-12-09 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
|
|
1QW6 | | RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH N-OMEGA-PROPYL-L-ARG. | | Descriptor: | Nitric-oxide synthase, brain, ZINC ION, ... | | Authors: | Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I. | | Deposit date: | 2003-09-01 | | Release date: | 2003-12-09 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
|
|
1QWC | | RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH W1400 INHIBITOR. | | Descriptor: | Nitric-oxide synthase, brain, ZINC ION, ... | | Authors: | Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I. | | Deposit date: | 2003-09-02 | | Release date: | 2003-12-09 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
|
|
1RH5 | | THE STRUCTURE OF A PROTEIN CONDUCTING CHANNEL | | Descriptor: | Preprotein translocase secY subunit, Preprotein translocase secE subunit, SecBeta | | Authors: | van den Berg, B., Clemons Jr., W.M., Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C., Rapoport, T.A. | | Deposit date: | 2003-11-13 | | Release date: | 2004-01-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray structure of a protein-conducting channel
Nature, 427, 2004
|
|
1RHZ | | THE STRUCTURE OF A PROTEIN CONDUCTING CHANNEL | | Descriptor: | Preprotein translocase secY subunit, Preprotein translocase secE subunit, SecBeta | | Authors: | van den Berg, B., Clemons Jr., W.M., Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C., Rapoport, T.A. | | Deposit date: | 2003-11-15 | | Release date: | 2004-01-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | X-ray structure of a protein-conducting channel.
Nature, 427, 2004
|
|
1TJP | | CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 1-[(2-HYDROXYLPHENYL)AMINO]3-GLYCEROLPHOSPHATE | | Descriptor: | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1-[(2-HYDROXYLPHENYL)AMINO]3-GLYCEROLPHOSPHATE, ... | | Authors: | Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M.F., Schlichting, I. | | Deposit date: | 2004-06-07 | | Release date: | 2005-12-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
|
|
1TJR | | CRYSTAL STRUCTURE OF WILD-TYPE BX1 COMPLEXED WITH A SULFATE ION | | Descriptor: | BX1, SULFATE ION | | Authors: | Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M.F., Schlichting, I. | | Deposit date: | 2004-06-07 | | Release date: | 2005-08-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
|
|
1ZVI | | RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN | | Descriptor: | Nitric-oxide synthase, brain, ZINC ION, ... | | Authors: | Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H. | | Deposit date: | 2005-06-02 | | Release date: | 2005-08-02 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
|
|
1ZVL | | RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN COMPLEXED WITH NATURAL SUBSTRATE L-ARG. | | Descriptor: | Nitric-oxide synthase, brain, ZINC ION, ... | | Authors: | Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H. | | Deposit date: | 2005-06-02 | | Release date: | 2005-08-02 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
|
|
3GFX | | KLEBSIELLA PNEUMONIAE BLRP1 PH 4.5 CALCIUM/CY-DIGMP COMPLEX | | Descriptor: | Klebsiella pneumoniae BlrP1, FLAVIN MONONUCLEOTIDE, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... | | Authors: | Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I. | | Deposit date: | 2009-02-27 | | Release date: | 2009-06-23 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
|
|
3GFY | | KLEBSIELLA PNEUMONIAE BLRP1 WITH FMN AND CYCLIC DIGMP, NO METAL IONS | | Descriptor: | Klebsiella pneumoniae BlrP1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FLAVIN MONONUCLEOTIDE | | Authors: | Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I. | | Deposit date: | 2009-02-27 | | Release date: | 2009-06-23 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
|
|
3GFZ | | KLEBSIELLA PNEUMONIAE BLRP1 PH 6 MANGANESE/CY-DIGMP COMPLEX | | Descriptor: | Klebsiella pneumoniae BlrP1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MANGANESE (II) ION, ... | | Authors: | Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I. | | Deposit date: | 2009-02-27 | | Release date: | 2009-06-23 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
|
|
3GG0 | | KLEBSIELLA PNEUMONIAE BLRP1 PH 9.0 MANGANESE/CY-DIGMP COMPLEX | | Descriptor: | Klebsiella pneumoniae BlrP1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MANGANESE (II) ION, ... | | Authors: | Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I. | | Deposit date: | 2009-02-27 | | Release date: | 2009-06-23 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
|
|
3GG1 | | KLEBSIELLA PNEUMONIAE BLRP1 PH 8.0 CALCIUM/CY-DIGMP COMPLEX | | Descriptor: | Klebsiella pneumoniae Blrp1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, ... | | Authors: | Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I. | | Deposit date: | 2009-02-27 | | Release date: | 2009-06-23 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
|
|
4J7Z | | THERMUS THERMOPHILUS DNAJ J- AND G/F-DOMAINS | | Descriptor: | Chaperone protein DnaJ 2, GLYCEROL | | Authors: | Barends, T.R.M., Brosi, R.W., Steinmetz, A., Scherer, A., Hartmann, E., Eschenbach, J., Lorenz, T., Seidel, R., Shoeman, R., Zimmermann, S., Bittl, R., Schlichting, I., Reinstein, J. | | Deposit date: | 2013-02-14 | | Release date: | 2013-07-31 | | Last modified: | 2013-10-09 | | Method: | X-RAY DIFFRACTION (1.64 Å), EPR | | Cite: | Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4J80 | | THERMUS THERMOPHILUS DNAJ | | Descriptor: | Chaperone protein DnaJ 2 | | Authors: | Barends, T.R.M., Brosi, R.W., Steinmetz, A., Scherer, A., Hartmann, E., Eschenbach, J., Lorenz, T., Seidel, R., Shoeman, R., Zimmermann, S., Bittl, R., Schlichting, I., Reinstein, J. | | Deposit date: | 2013-02-14 | | Release date: | 2013-07-31 | | Last modified: | 2013-10-09 | | Method: | X-RAY DIFFRACTION (2.9 Å), EPR | | Cite: | Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
5CMV | | ULTRAFAST DYNAMICS IN MYOGLOBIN: DARK-STATE, CO-LIGATED STRUCTURE | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | | Authors: | Barends, T.R.M., Foucar, L., Ardevol, A., Nass, K.J., Aquila, A., Botha, S., Doak, R.B., Falahati, K., Hartmann, E., Hilpert, M., Heinz, M., Hoffmann, M.C., Koefinger, J., Koglin, J., Kovacsova, G., Liang, M., Milathianaki, D., Lemke, H.T., Reinstein, J., Roome, C.M., Shoeman, R.L., Williams, G.J., Burghardt, I., Hummer, G., Boutet, S., Schlichting, I. | | Deposit date: | 2015-07-17 | | Release date: | 2015-09-16 | | Last modified: | 2018-11-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation.
Science, 350, 2015
|
|
5CN4 | | ULTRAFAST DYNAMICS IN MYOGLOBIN: -0.1 PS TIME DELAY | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | | Authors: | Barends, T.R.M., Foucar, L., Ardevol, A., Nass, K.J., Aquila, A., Botha, S., Doak, R.B., Falahati, K., Hartmann, E., Hilpert, M., Heinz, M., Hoffmann, M.C., Koefinger, J., Koglin, J., Kovacsova, G., Liang, M., Milathianaki, D., Lemke, H.T., Reinstein, J., Roome, C.M., Shoeman, R.L., Williams, G.J., Burghardt, I., Hummer, G., Boutet, S., Schlichting, I. | | Deposit date: | 2015-07-17 | | Release date: | 2015-09-16 | | Last modified: | 2018-11-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation.
Science, 350, 2015
|
|
