Author results

4HU3
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CRYSTAL STRUCTURE OF EAL DOMAIN OF THE E. COLI DOSP - MONOMERIC FORM
Descriptor:Oxygen sensor protein DosP
Authors:Tarnawski, M., Barends, T.R.M., Hartmann, E., Schlichting, I.
Deposit date:2012-11-02
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor.
Acta Crystallogr.,Sect.D, 69, 2013
4HU4
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CRYSTAL STRUCTURE OF EAL DOMAIN OF THE E. COLI DOSP - DIMERIC FORM
Descriptor:Oxygen sensor protein DosP
Authors:Tarnawski, M., Barends, T.R.M., Hartmann, E., Schlichting, I.
Deposit date:2012-11-02
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor.
Acta Crystallogr.,Sect.D, 69, 2013
1RD5
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE ALPHA CHAIN HOMOLOG BX1: A MEMBER OF THE CHEMICAL PLANT DEFENSE SYSTEM
Descriptor:Tryptophan synthase alpha chain, chloroplast, MALONIC ACID
Authors:Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M.F., Schlichting, I.
Deposit date:2003-11-05
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
1N9L
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CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN THE DARK STATE.
Descriptor:putative blue light receptor, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
1N9N
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CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN ILLUMINATED STATE. DATA SET OF A SINGLE CRYSTAL.
Descriptor:putative blue light receptor, FLAVIN MONONUCLEOTIDE
Authors:Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
1N9O
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CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN ILLUMINATED STATE. COMPOSITE DATA SET.
Descriptor:putative blue light receptor, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
1QW4
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CRYSTAL STRUCTURE OF MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH N-OMEGA-PROPYL-L-ARGININE.
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-08-31
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1QW5
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MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH W1400 INHIBITOR.
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-08-31
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1QW6
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH N-OMEGA-PROPYL-L-ARG.
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-09-01
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1QWC
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH W1400 INHIBITOR.
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-09-02
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1RH5
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THE STRUCTURE OF A PROTEIN CONDUCTING CHANNEL
Descriptor:Preprotein translocase secY subunit, Preprotein translocase secE subunit, SecBeta
Authors:van den Berg, B., Clemons Jr., W.M., Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C., Rapoport, T.A.
Deposit date:2003-11-13
Release date:2004-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-ray structure of a protein-conducting channel
Nature, 427, 2004
1RHZ
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THE STRUCTURE OF A PROTEIN CONDUCTING CHANNEL
Descriptor:Preprotein translocase secY subunit, Preprotein translocase secE subunit, SecBeta
Authors:van den Berg, B., Clemons Jr., W.M., Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C., Rapoport, T.A.
Deposit date:2003-11-15
Release date:2004-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of a protein-conducting channel.
Nature, 427, 2004
1TJP
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CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 1-[(2-HYDROXYLPHENYL)AMINO]3-GLYCEROLPHOSPHATE
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1-[(2-HYDROXYLPHENYL)AMINO]3-GLYCEROLPHOSPHATE, ...
Authors:Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M.F., Schlichting, I.
Deposit date:2004-06-07
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
1TJR
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CRYSTAL STRUCTURE OF WILD-TYPE BX1 COMPLEXED WITH A SULFATE ION
Descriptor:BX1, SULFATE ION
Authors:Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M.F., Schlichting, I.
Deposit date:2004-06-07
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
1ZVI
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H.
Deposit date:2005-06-02
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
1ZVL
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN COMPLEXED WITH NATURAL SUBSTRATE L-ARG.
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H.
Deposit date:2005-06-02
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
3GFX
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KLEBSIELLA PNEUMONIAE BLRP1 PH 4.5 CALCIUM/CY-DIGMP COMPLEX
Descriptor:Klebsiella pneumoniae BlrP1, FLAVIN MONONUCLEOTIDE, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ...
Authors:Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I.
Deposit date:2009-02-27
Release date:2009-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
3GFY
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KLEBSIELLA PNEUMONIAE BLRP1 WITH FMN AND CYCLIC DIGMP, NO METAL IONS
Descriptor:Klebsiella pneumoniae BlrP1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FLAVIN MONONUCLEOTIDE
Authors:Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I.
Deposit date:2009-02-27
Release date:2009-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
3GFZ
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KLEBSIELLA PNEUMONIAE BLRP1 PH 6 MANGANESE/CY-DIGMP COMPLEX
Descriptor:Klebsiella pneumoniae BlrP1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MANGANESE (II) ION, ...
Authors:Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I.
Deposit date:2009-02-27
Release date:2009-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
3GG0
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KLEBSIELLA PNEUMONIAE BLRP1 PH 9.0 MANGANESE/CY-DIGMP COMPLEX
Descriptor:Klebsiella pneumoniae BlrP1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MANGANESE (II) ION, ...
Authors:Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I.
Deposit date:2009-02-27
Release date:2009-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
3GG1
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KLEBSIELLA PNEUMONIAE BLRP1 PH 8.0 CALCIUM/CY-DIGMP COMPLEX
Descriptor:Klebsiella pneumoniae Blrp1, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, ...
Authors:Barends, T., Hartmann, E., Griese, J., Beitlich, T., Kirienko, N., Ryjenkov, D., Reinstein, J., Shoeman, R., Gomelsky, M., Schlichting, I.
Deposit date:2009-02-27
Release date:2009-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
Nature, 459, 2009
4J7Z
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THERMUS THERMOPHILUS DNAJ J- AND G/F-DOMAINS
Descriptor:Chaperone protein DnaJ 2, GLYCEROL
Authors:Barends, T.R.M., Brosi, R.W., Steinmetz, A., Scherer, A., Hartmann, E., Eschenbach, J., Lorenz, T., Seidel, R., Shoeman, R., Zimmermann, S., Bittl, R., Schlichting, I., Reinstein, J.
Deposit date:2013-02-14
Release date:2013-07-31
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.64 Å), EPR
Cite:Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
4J80
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THERMUS THERMOPHILUS DNAJ
Descriptor:Chaperone protein DnaJ 2
Authors:Barends, T.R.M., Brosi, R.W., Steinmetz, A., Scherer, A., Hartmann, E., Eschenbach, J., Lorenz, T., Seidel, R., Shoeman, R., Zimmermann, S., Bittl, R., Schlichting, I., Reinstein, J.
Deposit date:2013-02-14
Release date:2013-07-31
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.9 Å), EPR
Cite:Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
5CMV
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ULTRAFAST DYNAMICS IN MYOGLOBIN: DARK-STATE, CO-LIGATED STRUCTURE
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Barends, T.R.M., Foucar, L., Ardevol, A., Nass, K.J., Aquila, A., Botha, S., Doak, R.B., Falahati, K., Hartmann, E., Hilpert, M., Heinz, M., Hoffmann, M.C., Koefinger, J., Koglin, J., Kovacsova, G., Liang, M., Milathianaki, D., Lemke, H.T., Reinstein, J., Roome, C.M., Shoeman, R.L., Williams, G.J., Burghardt, I., Hummer, G., Boutet, S., Schlichting, I.
Deposit date:2015-07-17
Release date:2015-09-16
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation.
Science, 350, 2015
5CN4
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ULTRAFAST DYNAMICS IN MYOGLOBIN: -0.1 PS TIME DELAY
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Barends, T.R.M., Foucar, L., Ardevol, A., Nass, K.J., Aquila, A., Botha, S., Doak, R.B., Falahati, K., Hartmann, E., Hilpert, M., Heinz, M., Hoffmann, M.C., Koefinger, J., Koglin, J., Kovacsova, G., Liang, M., Milathianaki, D., Lemke, H.T., Reinstein, J., Roome, C.M., Shoeman, R.L., Williams, G.J., Burghardt, I., Hummer, G., Boutet, S., Schlichting, I.
Deposit date:2015-07-17
Release date:2015-09-16
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation.
Science, 350, 2015
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