Author results

3L50
  • Download 3l50
  • View 3l50
Molmil generated image of 3l50
THE CRYSTAL STRUCTURE OF HUMAN GLIA MATURATION FACTOR, GAMMA (GMFG)
Descriptor:Glia maturation factor gamma, CHLORIDE ION
Authors:Ugochukwu, E., Pilka, E., Krysztofinska, E., Hapka, E., Krojer, T., Muniz, J., Vollmar, M., Pike, A.C.W., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-12-21
Release date:2010-02-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human Glia Maturation Factor, Gamma (GMFG)
To be Published
3IAR
  • Download 3iar
  • View 3iar
Molmil generated image of 3iar
THE CRYSTAL STRUCTURE OF HUMAN ADENOSINE DEAMINASE
Descriptor:Adenosine deaminase, (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, NICKEL (II) ION, ...
Authors:Ugochukwu, E., Zhang, Y., Hapka, E., Yue, W.W., Bray, J.E., Muniz, J., Burgess-Brown, N., Chaikuad, A., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-07-14
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The crystal structure of human adenosine deaminase
To be Published
3KVW
  • Download 3kvw
  • View 3kvw
Molmil generated image of 3kvw
CRYSTAL STRUCTURE OF DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 2 (DYRK2) IN COMPLEX WITH AN INDIRUBIN LIGAND
Descriptor:Dual specificity tyrosine-phosphorylation-regulated kinase 2, (2Z,3E)-7'-bromo-3-(hydroxyimino)-2'-oxo-1,1',2',3-tetrahydro-2,3'-biindole-5-carboxylic acid, CHLORIDE ION
Authors:Filippakopoulos, P., Myrianthopoulos, V., Kritsanida, M., Magiatis, P., Skaltsounis, A.L., Soundararajan, M., Krojer, T., Gileadi, O., Hapka, E., Fedorov, O., Berridge, G., Wang, J., Shrestha, L., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Mikros, E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2009-11-30
Release date:2010-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand
To be Published
3K2L
  • Download 3k2l
  • View 3k2l
Molmil generated image of 3k2l
CRYSTAL STRUCTURE OF DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 2 (DYRK2)
Descriptor:Dual specificity tyrosine-phosphorylation-regulated kinase 2, SULFATE ION, SODIUM ION, ...
Authors:Filippakopoulos, P., Myrianthopoulos, V., Soundararajan, M., Krojer, T., Hapka, E., Fedorov, O., Berridge, G., Wang, J., Shrestha, L., Pike, A.C.W., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Mikros, E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2009-09-30
Release date:2009-10-13
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition.
Structure, 21, 2013
3LM0
  • Download 3lm0
  • View 3lm0
Molmil generated image of 3lm0
CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE 17B (STK17B)
Descriptor:Serine/threonine-protein kinase 17B, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-5-methylpyrimidin-2-yl}amino)phenyl]acetonitrile, 1,2-ETHANEDIOL, ...
Authors:Ugochukwu, E., Soundararajan, M., Rellos, P., Fedorov, O., Phillips, C., Wang, J., Hapka, E., Filippakopoulos, P., Chaikuad, A., Pike, A.C.W., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-03-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:

3LM5
  • Download 3lm5
  • View 3lm5
Molmil generated image of 3lm5
CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE 17B (STK17B) IN COMPLEX WITH QUERCETIN
Descriptor:Serine/threonine-protein kinase 17B, 3,5,7,3',4'-PENTAHYDROXYFLAVONE
Authors:Ugochukwu, E., Soundararajan, M., Rellos, P., Fedorov, O., Phillips, C., Wang, J., Hapka, E., Filippakopoulos, P., Chaikuad, A., Pike, A.C.W., Carpenter, L., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-03-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:

2WM8
  • Download 2wm8
  • View 2wm8
Molmil generated image of 2wm8
CRYSTAL STRUCTURE OF HUMAN MAGNESIUM-DEPENDENT PHOSPHATASE 1 OF THE HALOACID DEHALOGENASE SUPERFAMILY (MGC5987)
Descriptor:MAGNESIUM-DEPENDENT PHOSPHATASE 1, 1,2-ETHANEDIOL
Authors:Yue, W.W., Shafqat, N., Pike, A.C.W., Chaikuad, A., Bray, J.E., Pilka, E.W., Burgess-Brown, N., Hapka, E., Filippakopoulos, P., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
Deposit date:2009-06-30
Release date:2009-07-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Human Magnesium-Dependent Phosphatase 1 of the Haloacid Dehalogenase Superfamily (Mgc5987)
To be Published