3IAR

The crystal structure of human adenosine deaminase

Summary for 3IAR

• Entry DOI: 10.2210/pdb3iar/pdb
• Related: 1KRM
• Descriptor: Adenosine deaminase, (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, NICKEL (II) ION, ... (6 entities in total)
• Functional Keywords: deaminase, adenosine deaminase, adenosine, purine metabolism, structural genomics, structural genomics consortium, sgc, disease mutation, hereditary hemolytic anemia, hydrolase, nucleotide metabolism, scid
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Peripheral membrane protein; Extracellular side: P00813
• Total number of polymer chains: 1
• Total formula weight: 41908.03

Authors

Ugochukwu, E.,Zhang, Y.,Hapka, E.,Yue, W.W.,Bray, J.E.,Muniz, J.,Burgess-Brown, N.,Chaikuad, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Kavanagh, K.L.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2009-07-14, release date: 2009-08-11, Last modification date: 2023-09-06)

• Primary citation: Ugochukwu, E.,Zhang, Y.,Hapka, E.,Yue, W.W.,Bray, J.E.,Muniz, J.,Burgess-Brown, N.,Chaikuad, A.,Kavanagh, K.L.,Oppermann, U.; The crystal structure of human adenosine deaminase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.52 Å)