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6F0G
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BU of 6f0g by Molmil
Crystal structure ASF1-ip3
Descriptor: Histone chaperone ASF1A, SULFATE ION, ip3
Authors:Gaubert, A, Guichard, B, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0F
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BU of 6f0f by Molmil
Crystal structure ASF1-ip2_s
Descriptor: Histone chaperone ASF1A, ip2_s
Authors:Gaubert, A, Guichard, B, Murciano, B, Le Du, M.H, Ochsenbein, F, Guerois, R, Andreani, J.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0H
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BU of 6f0h by Molmil
Crystal structure ASF1-ip4
Descriptor: CITRIC ACID, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6ZUF
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BU of 6zuf by Molmil
Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone
Descriptor: C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Mbianda, J, Perrin, E.M, Guerois, R, Legrand, P, Traore, S, Douat, C, Guichard, G, Ochsenbein, F.
Deposit date:2020-07-22
Release date:2021-06-09
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
Sci Adv, 7, 2021
4UUZ
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BU of 4uuz by Molmil
MCM2-histone complex
Descriptor: DNA REPLICATION LICENSING FACTOR MCM2, HISTONE H3, HISTONE H4
Authors:Richet, N, Liu, D, Legrand, P, Bakail, M, Compper, C, Besle, A, Guerois, R, Ochsenbein, F.
Deposit date:2014-08-01
Release date:2015-02-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Insight Into How the Human Helicase Subunit Mcm2 May Act as a Histone Chaperone Together with Asf1 at the Replication Fork.
Nucleic Acids Res., 43, 2015
2YGV
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BU of 2ygv by Molmil
Conserved N-terminal domain of the yeast Histone Chaperone Asf1 in complex with the C-terminal fragment of Rad53
Descriptor: GLYCEROL, HISTONE CHAPERONE ASF1, SERINE/THREONINE-PROTEIN KINASE RAD53, ...
Authors:Jiao, Y, Seeger, K, Murciano, B, Ledu, M.H, Charbonnier, J.B, Legrand, P, Lautrette, A, Gaubert, A, Mousson, F, Guerois, R, Mann, C, Ochsenbein, F.
Deposit date:2011-04-21
Release date:2012-02-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Surprising Complexity of the Asf1 Histone Chaperone-Rad53 Kinase Interaction
Proc.Natl.Acad.Sci.USA, 109, 2012
2J8A
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BU of 2j8a by Molmil
X-ray structure of the N-terminus RRM domain of Set1
Descriptor: HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC
Authors:Tresaugues, L, Dehe, P.M, Guerois, R, Rodriguez-Gil, A, Varlet, I, Salah, P, Pamblanco, M, Luciano, P, Quevillon-Cheruel, S, Sollier, J, Leulliot, N, Couprie, J, Tordera, V, Zinn-Justin, S, Chavez, S, Van Tilbeurgh, H, Geli, V.
Deposit date:2006-10-24
Release date:2007-03-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-Ray Structure of the N-Terminus Rrm Domain of Set1
To be Published
1TEY
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BU of 1tey by Molmil
NMR structure of human histone chaperone, ASF1A
Descriptor: ASF1 anti-silencing function 1 homolog A
Authors:Mousson, F, Lautrette, A, Thuret, J.Y, Agez, M, Amigues, B, Courbeyrette, R, Neumann, J.M, Guerois, R, Mann, C, Ochsenbein, F.
Deposit date:2004-05-26
Release date:2005-04-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis for the interaction of Asf1 with histone H3 and its functional implications.
Proc.Natl.Acad.Sci.Usa, 102, 2005
6GW7
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BU of 6gw7 by Molmil
The CTD of HpDprA, a DNA binding Winged Helix domain which do not bind dsDNA
Descriptor: DNA protecting protein DprA
Authors:Lisboa, J, Celma, L, Sanchez, D, Marquis, M, Andreani, J, Guerois, R, Ochsenbein, F, Durand, D, Marsin, S, Cuniasse, P, Radicella, J.P, Quevillon-Cheruel, S.
Deposit date:2018-06-22
Release date:2019-04-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The C-terminal domain of HpDprA is a DNA-binding winged helix domain that does not bind double-stranded DNA.
Febs J., 286, 2019
4NFU
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BU of 4nfu by Molmil
Structure of the central plant immunity signaling node EDS1 in complex with its interaction partner SAG101
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, EDS1, ISOPROPYL ALCOHOL, ...
Authors:Wagner, S, Stuttmann, J, Rietz, S, Guerois, R, Niefind, K, Parker, J.E.
Deposit date:2013-11-01
Release date:2013-12-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity.
Cell Host Microbe, 14, 2013
1SSF
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BU of 1ssf by Molmil
Solution structure of the mouse 53BP1 fragment (residues 1463-1617)
Descriptor: Transformation related protein 53 binding protein 1
Authors:Charier, G, Couprie, J, Alpha-Bazin, B, Meyer, V, Quemeneur, E, Guerois, R, Callebaut, I, Gilquin, B, Zinn-Justin, S.
Deposit date:2004-03-24
Release date:2004-09-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Tudor Tandem of 53BP1; A New Structural Motif Involved in DNA and RG-Rich Peptide Binding
Structure, 12, 2004
4A3V
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BU of 4a3v by Molmil
yeast regulatory particle proteasome assembly chaperone Hsm3 in complex with Rpt1 C-terminal fragment
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 7 HOMOLOG, DNA MISMATCH REPAIR PROTEIN HSM3, LINKER
Authors:Richet, N, Barrault, M.B, Godart, C, Murciano, B, Le Tallec, B, Rousseau, E, Ledu, M.H, Charbonnier, J.B, Legrand, P, Guerois, R, Peyroche, A, Ochsenbein, F.
Deposit date:2011-10-04
Release date:2012-04-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Dual Functions of the Hsm3 Protein in Chaperoning and Scaffolding Regulatory Particle Subunits During the Proteasome Assembly.
Proc.Natl.Acad.Sci.USA, 109, 2012
4A3T
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BU of 4a3t by Molmil
yeast regulatory particle proteasome assembly chaperone Hsm3
Descriptor: DNA MISMATCH REPAIR PROTEIN HSM3
Authors:Richet, N, Barrault, M.B, Godart, C, Murciano, B, Le Tallec, B, Rousseau, E, Ledu, M.H, Charbonnier, J.B, Legrand, P, Guerois, R, Peyroche, A, Ochsenbein, F.
Deposit date:2011-10-04
Release date:2012-04-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dual Functions of the Hsm3 Protein in Chaperoning and Scaffolding Regulatory Particle Subunits During the Proteasome Assembly.
Proc.Natl.Acad.Sci.USA, 109, 2012
2IIJ
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BU of 2iij by Molmil
Structure of human Asf1a in complex with histone H3
Descriptor: ASF1A protein, Histone H3
Authors:Agez, M, Guerois, R, van Heijenoort, C, Mann, C, Ochsenbein, F.
Deposit date:2006-09-28
Release date:2007-02-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the histone chaperone asf1 bound to the histone h3 C-terminal helix and functional insights.
Structure, 15, 2007
7P0H
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BU of 7p0h by Molmil
Crystal structure of Helicobacter pylori ComF fused to an artificial alphaREP crystallization helper(named B2)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GLYCEROL, Helicobacter pylori ComF fused to an artificial alphaREP crystallization helper (named B2), ...
Authors:Celma, L, Walbott, H, Legrand, P, Quevillon-Cheruel, S.
Deposit date:2021-06-29
Release date:2022-04-06
Last modified:2022-04-27
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:ComFC mediates transport and handling of single-stranded DNA during natural transformation.
Nat Commun, 13, 2022
4Y05
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BU of 4y05 by Molmil
KIF2C short Loop2 construct
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION, ...
Authors:Wang, W, Knossow, M, Gigant, B.
Deposit date:2015-02-05
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.
J.Biol.Chem., 290, 2015
5MLL
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BU of 5mll by Molmil
Structure of HpDprA at 1.9 Angstroms resolution
Descriptor: 1,2-ETHANEDIOL, DNA processing chain A (DprA)
Authors:Lisboa, J, Quevillon-Cheruel, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The C-terminal domain of HpDprA is a DNA-binding Winged Helix domain that does not bind double-stranded DNA.
FEBS J., 2019
6ERF
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BU of 6erf by Molmil
Complex of APLF factor and Ku heterodimer bound to DNA
Descriptor: Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ...
Authors:Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat.Struct.Mol.Biol., 25, 2018
3Q4F
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BU of 3q4f by Molmil
Crystal structure of xrcc4/xlf-cernunnos complex
Descriptor: DNA repair protein XRCC4, Non-homologous end-joining factor 1
Authors:Ropars, V, Legrand, P, Charbonnier, J.B.
Deposit date:2010-12-23
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Proc.Natl.Acad.Sci.USA, 108, 2011
6RMN
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BU of 6rmn by Molmil
DNA mismatch repair proteins MLH1 and MLH3
Descriptor: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION
Authors:Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2019-05-07
Release date:2021-05-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
6HKS
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BU of 6hks by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
Descriptor: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Haouz, A, Caillet-Saguy, C.
Deposit date:2018-09-07
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1944108 Å)
Cite:Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Sci Rep, 9, 2019
6EHI
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BU of 6ehi by Molmil
NucT from Helicobacter pylori
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Celma, L, Li de la Sierra-Gallay, I, Quevillon-Cheruel, S.
Deposit date:2017-09-13
Release date:2018-01-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity.
PLoS ONE, 12, 2017
6ERG
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BU of 6erg by Molmil
Complex of XLF and heterodimer Ku bound to DNA
Descriptor: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
Authors:Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERH
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BU of 6erh by Molmil
Complex of XLF and heterodimer Ku bound to DNA
Descriptor: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
Authors:Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
4PXJ
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BU of 4pxj by Molmil
Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3
Descriptor: 1,2-ETHANEDIOL, C-Jun-amino-terminal kinase-interacting protein 3, GUANIDINE, ...
Authors:Llinas, P, Menetrey, J.
Deposit date:2014-03-24
Release date:2015-06-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of a truncated form of leucine zipper II of JIP3 reveals an unexpected antiparallel coiled-coil arrangement.
Acta Crystallogr F Struct Biol Commun, 72, 2016

 

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