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6FJH
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CRYSTAL STRUCTURE OF THE SELENIATED LKCE FROM STREPTOMYCES ROCHEI
Descriptor:LkcE, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, ...
Authors:Dorival, J., Risser, F., Jacob, C., Collin, S., Drager, G., Kirschning, A., Paris, C., Chagot, B., Gruez, A., Weissman, K.J.
Deposit date:2018-01-22
Release date:2018-09-19
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.
Nat Commun, 9, 2018
6F7V
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CRYSTAL STRUCTURE OF LKCE E64Q MUTANT IN COMPLEX WITH LC-KA05
Descriptor:LkcE, FLAVIN-ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Dorival, J., Risser, F., Jacob, C., Collin, S., Drager, G., Kirschning, A., Paris, C., Chagot, B., Gruez, A., Weissman, K.J.
Deposit date:2017-12-12
Release date:2018-09-19
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.
Nat Commun, 9, 2018
6F7L
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CRYSTAL STRUCTURE OF LKCE R326Q MUTANT IN COMPLEX WITH ITS SUBSTRATE
Descriptor:Amine oxidase LkcE, FLAVIN-ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Dorival, J., Risser, F., Jacob, C., Collin, S., Drager, G., Kirschning, A., Paris, C., Chagot, B., Gruez, A., Weissman, K.J.
Deposit date:2017-12-11
Release date:2018-09-19
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.
Nat Commun, 9, 2018
6F32
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CRYSTAL STRUCTURE OF A DUAL FUNCTION AMINE OXIDASE/CYCLASE IN COMPLEX WITH SUBSTRATE ANALOGUES
Descriptor:Amine oxidase LkcE, FLAVIN-ADENINE DINUCLEOTIDE, ACETATE ION, ...
Authors:Dorival, J., Risser, F., Jacob, C., Collin, S., Drager, G., Kirschning, A., Paris, C., Chagot, B., Gruez, A., Weissman, K.J.
Deposit date:2017-11-27
Release date:2018-09-19
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.
Nat Commun, 9, 2018
2N5D
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NMR STRUCTURE OF PKS DOMAINS
Descriptor:fusion protein of two PKS domains
Authors:Dorival, J., Annaval, T., Risser, F., Collin, S., Roblin, P., Jacob, C., Gruez, A., Chagot, B., Weissman, K.J.
Deposit date:2015-07-14
Release date:2016-03-23
Last modified:2016-12-07
Method:SOLUTION NMR
Cite:Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase.
J.Am.Chem.Soc., 138, 2016
2MF4
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1H, 13C, 15N CHEMICAL SHIFT ASSIGNMENTS OF STREPTOMYCES VIRGINIAE VIRA ACP5A
Descriptor:Hybrid polyketide synthase-non ribosomal peptide synthetase
Authors:Davison, J., Dorival, J., Rabeharindranto, M.H., Mazon, H., Chagot, B., Gruez, A., Weissman, K.J.
Deposit date:2013-10-05
Release date:2014-06-04
Method:SOLUTION NMR
Cite:NMR assignements of ACP5a
To be Published
4CA3
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SOLUTION STRUCTURE OF STREPTOMYCES VIRGINIAE VIRA ACP5B
Descriptor:HYBRID POLYKETIDE SYNTHASE-NON RIBOSOMAL PEPTIDE SYNTHETASE
Authors:Davison, J., Dorival, J., Rabeharindranto, M.H., Chagot, B., Gruez, A., Weissman, K.J.
Deposit date:2013-10-05
Release date:2014-06-04
Method:SOLUTION NMR
Cite:Insights Into the Function of Trans-Acyl Transferase Polyketide Synthases from the Saxs Structure of a Complete Module.
Chem.Sci., 2014
4LRS
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CRYSTAL AND SOLUTION STRUCTURES OF THE BIFUNCTIONAL ENZYME (ALDOLASE/ALDEHYDE DEHYDROGENASE) FROM THERMOMONOSPORA CURVATA, REVEAL A COFACTOR-BINDING DOMAIN MOTION DURING NAD+ AND COA ACCOMMODATION WHITHIN THE SHARED COFACTOR-BINDING SITE
Descriptor:4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, Symmetric aldolase, ...
Authors:Fischer, B., Branlant, G., Talfournier, F., Gruez, A.
Deposit date:2013-07-20
Release date:2013-09-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
To be Published
4LRT
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CRYSTAL AND SOLUTION STRUCTURES OF THE BIFUNCTIONAL ENZYME (ALDOLASE/ALDEHYDE DEHYDROGENASE) FROM THERMOMONOSPORA CURVATA, REVEAL A COFACTOR-BINDING DOMAIN MOTION DURING NAD+ AND COA ACCOMMODATION WHITHIN THE SHARED COFACTOR-BINDING SITE
Descriptor:4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, PYRUVIC ACID, ...
Authors:Fischer, B., Branlant, G., Talfournier, F., Gruez, A.
Deposit date:2013-07-20
Release date:2013-09-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
To be Published
3MMH
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X-RAY STRUCTURE OF FREE METHIONINE-R-SULFOXIDE REDUCTASE FROM NEISSERIA MENINGITIDIS IN COMPLEX WITH ITS SUBSTRATE
Descriptor:Methionine-R-sulfoxide reductase, METHIONINE SULFOXIDE, MAGNESIUM ION, ...
Authors:Gruez, A., Libiad, M., Boschi-Muller, S., Branlant, G.
Deposit date:2010-04-19
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural and Biochemical Characterization of Free Methionine-R-sulfoxide Reductase from Neisseria meningitidis.
J.Biol.Chem., 285, 2010
3CDU
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 RNA-DEPENDENT RNA POLYMERASE (3DPOL) IN COMPLEX WITH A PYROPHOSPHATE
Descriptor:RNA-directed RNA polymerase 3D-POL, CHLORIDE ION, SULFATE ION, ...
Authors:Gruez, A., Selisko, B., Roberts, M., Bricogne, G., Bussetta, C., Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3CDW
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 RNA-DEPENDENT RNA POLYMERASE (3DPOL) IN COMPLEX WITH PROTEIN PRIMER VPG AND A PYROPHOSPHATE
Descriptor:RNA-directed RNA polymerase 3D-POL, Protein 3B, CHLORIDE ION, ...
Authors:Gruez, A., Selisko, B., Roberts, M., Bricogne, G., Bussetta, C., Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
2VJP
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FORMYL-COA TRANSFERASE MUTANT VARIANT W48F
Descriptor:FORMYL-COENZYME A TRANSFERASE, SODIUM ION
Authors:Toyota, C.G., Berthold, C.L., Gruez, A., Jonsson, S., Lindqvist, Y., Cambillau, C., Richards, N.G.J.
Deposit date:2007-12-11
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Differential Substrate Specificity and Kinetic Behavior of Escherichia Coli Yfdw and Oxalobacter Formigenes Formyl Coenzyme a Transferase.
J.Bacteriol., 190, 2008
2VJQ
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FORMYL-COA TRANSFERASE MUTANT VARIANT W48Q
Descriptor:FORMYL-COENZYME A TRANSFERASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Toyota, C.G., Berthold, C.L., Gruez, A., Jonsson, S., Lindqvist, Y., Cambillau, C., Richards, N.G.J.
Deposit date:2007-12-11
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differential Substrate Specificity and Kinetic Behavior of Escherichia Coli Yfdw and Oxalobacter Formigenes Formyl Coenzyme a Transferase.
J.Bacteriol., 190, 2008
3BJH
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SOFT-SAD CRYSTAL STRUCTURE OF A PHEROMONE BINDING PROTEIN FROM THE HONEYBEE APIS MELLIFERA L.
Descriptor:Pheromone-binding protein ASP1, N-BUTYL-BENZENESULFONAMIDE, GLYCEROL
Authors:Lartigue, A., Gruez, A., Briand, L., Blon, F., Bezirard, V., Walsh, M., Pernollet, J.C., Tegoni, M., Cambillau, C.
Deposit date:2007-12-04
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Sulfur single-wavelength anomalous diffraction crystal structure of a pheromone-binding protein from the honeybee Apis mellifera L.
J.Biol.Chem., 279, 2004
2HFZ
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CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase(NS5), MAGNESIUM ION, ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-26
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HCS
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CRYSTAL STRUCTURE OF RNA DEPENDANT RNA POLYMERASE DOMAIN OF WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5), ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-18
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HCN
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CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5), CALCIUM ION, ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-17
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2FAV
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CRYSTAL STRUCTURE OF SARS MACRO DOMAIN IN COMPLEX WITH ADP-RIBOSE AT 1.8 A RESOLUTION
Descriptor:Replicase polyprotein 1ab (pp1ab) (ORF1AB), ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2005-12-08
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains.
J.Virol., 80, 2006
1W8G
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CRYSTAL STRUCTURE OF E. COLI K-12 YGGS
Descriptor:HYPOTHETICAL UPF0001 PROTEIN YGGS, PYRIDOXAL-5'-PHOSPHATE, ISOCITRIC ACID
Authors:Sulzenbacher, G., Gruez, A., Spinelli, S., Roig-Zamboni, V., Pagot, F., Bignon, C., Vincentelli, R., Cambillau, C.
Deposit date:2004-09-21
Release date:2006-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of E. Coli K-12 Yggs
To be Published
1WNB
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ESCHERICHIA COLI YDCW GENE PRODUCT IS A MEDIUM-CHAIN ALDEHYDE DEHYDROGENASE (COMPLEXED WITH NADH AND BETAINE ALDEHYDE)
Descriptor:Putative betaine aldehyde dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BETAINE ALDEHYDE
Authors:Gruez, A., Roig-Zamboni, V., Tegoni, M., Cambillau, C.
Deposit date:2004-07-29
Release date:2004-10-05
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure and Kinetics Identify Escherichia coli YdcW Gene Product as a Medium-chain Aldehyde Dehydrogenase
J.Mol.Biol., 343, 2004
1WND
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ESCHERICHIA COLI YDCW GENE PRODUCT IS A MEDIUM-CHAIN ALDEHYDE DEHYDROGENASE AS DETERMINED BY KINETICS AND CRYSTAL STRUCTURE
Descriptor:Putative betaine aldehyde dehydrogenase, CALCIUM ION
Authors:Gruez, A., Roig-Zamboni, V., Tegoni, M., Cambillau, C.
Deposit date:2004-07-29
Release date:2004-10-05
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure and Kinetics Identify Escherichia coli YdcW Gene Product as a Medium-chain Aldehyde Dehydrogenase
J.Mol.Biol., 343, 2004
1PT5
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CRYSTAL STRUCTURE OF GENE YFDW OF E. COLI
Descriptor:Hypothetical protein yfdW, ACETYL COENZYME *A
Authors:Gruez, A., Roig-Zamboni, V., Valencia, C., Campanacci, V., Cambillau, C.
Deposit date:2003-06-23
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Escherichia coli YfdW Gene Product Reveals a New Fold of Two Interlaced Rings Identifying a Wide Family of CoA Transferases
J.Biol.Chem., 278, 2003
1PT7
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CRYSTAL STRUCTURE OF THE APO-FORM OF THE YFDW GENE PRODUCT OF E. COLI
Descriptor:Hypothetical protein yfdW, PHOSPHATE ION, GLYCEROL
Authors:Gruez, A., Roig-Zamboni, V., Valencia, C., Campanacci, V., Cambillau, C.
Deposit date:2003-06-23
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the Escherichia coli yfdW gene product reveals a New fold of two interlaced rings identifying a wide family of CoA transferases.
J.Biol.Chem., 278, 2003
1PT8
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CRYSTAL STRUCTURE OF THE YFDW GENE PRODUCT OF E. COLI, IN COMPLEX WITH OXALATE AND ACETYL-COA
Descriptor:Hypothetical protein yfdW, OXALATE ION, ACETYL COENZYME *A, ...
Authors:Gruez, A., Roig-Zamboni, V., Valencia, C., Campanacci, V., Cambillau, C.
Deposit date:2003-06-23
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the Escherichia coli yfdW gene product reveals a new fold of two interlaced rings identifying a wide family of CoA transferases.
J.Biol.Chem., 278, 2003
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