Author results

5JNX
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THE 6.6 A CRYO-EM STRUCTURE OF THE FULL-LENGTH HUMAN NPC1 IN COMPLEX WITH THE CLEAVED GLYCOPROTEIN OF EBOLA VIRUS
Descriptor:Niemann-Pick C1 protein, Envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gong, X., Qian, H.W., Zhou, X.H., Wu, J.P., Wan, T., Shi, Y., Gao, F., Zhou, Q., Yan, N.
Deposit date:2016-05-01
Release date:2016-06-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (6.56 Å)
Cite:Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection
Cell, 165, 2016
6A0N
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THE CRYSTAL STRUCTURE OF APO-LPG2622
Descriptor:Lpg2622
Authors:Gong, X., Ge, H.
Deposit date:2018-06-05
Release date:2018-09-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila
FEBS Lett., 592, 2018
6A0Q
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THE CRYSTAL STRUCTURE OF LPG2622_E64 COMPLEX
Descriptor:Lpg2622, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
Authors:Gong, X., Ge, H.
Deposit date:2018-06-06
Release date:2018-09-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila
FEBS Lett., 592, 2018
4TTP
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CRYSTAL STRUCTURE OF LEGIONELLA PNEUMOPHILA DEPHOSPHO-COA KINASE IN APO-FORM
Descriptor:Dephospho-CoA kinase
Authors:Gong, X., Ge, H.
Deposit date:2014-06-22
Release date:2014-12-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Legionella pneumophila dephospho-CoA kinase reveals a non-canonical conformation of P-loop.
J.Struct.Biol., 188, 2014
3JD8
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CRYO-EM STRUCTURE OF THE FULL-LENGTH HUMAN NPC1 AT 4.4 ANGSTROM
Descriptor:Niemann-Pick C1 protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Gong, X., Qian, H.W., Zhou, X.H., Wu, J.P., Zhou, Q., Yan, N.
Deposit date:2016-05-01
Release date:2016-06-01
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:The structure of Niemann-Pick C1 protein
To Be Published
4YHC
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CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF SCAP FROM FISSION YEAST
Descriptor:Sterol regulatory element-binding protein cleavage-activating protein, CITRIC ACID
Authors:Gong, X., Li, J.X., Wu, J.P., Yan, C.Y., Yan, N.
Deposit date:2015-02-27
Release date:2015-04-01
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.
Cell Res., 25, 2015
5GPD
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CRYSTAL STRUCTURE OF THE BINDING DOMAIN OF SREBP FROM FISSION YEAST
Descriptor:Sterol regulatory element-binding protein 1
Authors:Gong, X., Qian, H.W., Wu, J.P., Yan, N.
Deposit date:2016-08-01
Release date:2016-11-23
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Cell Res., 26, 2016
5GRS
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COMPLEX STRUCTURE OF THE FISSION YEAST SREBP-SCAP BINDING DOMAINS
Descriptor:Sterol regulatory element-binding protein cleavage-activating protein, Sterol regulatory element-binding protein 1
Authors:Gong, X., Qian, H.W., Wu, J.P., Yan, N.
Deposit date:2016-08-12
Release date:2016-12-14
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Cell Res., 26, 2016
6DMB
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CRYO-EM STRUCTURE OF HUMAN PTCH1
Descriptor:Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL HEMISUCCINATE
Authors:Yan, N., Gong, X., Qian, H.W.
Deposit date:2018-06-04
Release date:2018-07-11
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMO
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CRYO-EM STRUCTURE OF HUMAN PTCH1 WITH THREE MUTATIONS L282Q/T500F/P504L
Descriptor:Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE
Authors:Yan, N., Gong, X., Qian, H.W.
Deposit date:2018-06-05
Release date:2018-07-11
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMY
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CRYO-EM STRUCTURE OF HUMAN PTCH1 AND SHHN COMPLEX
Descriptor:Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Yan, N., Gong, X., Qian, H.W.
Deposit date:2018-06-05
Release date:2018-07-11
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
5ESW
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CRYSTAL STRUCTURE OF APO HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE FROM LEGIONELLA PNEUMOPHILA
Descriptor:Purine/pyrimidine phosphoribosyltransferase, PHOSPHATE ION
Authors:Zhang, N., Gong, X., Lu, M., Chen, X., Qin, X., Ge, H.
Deposit date:2015-11-17
Release date:2016-03-30
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
5ESX
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CRYSTAL STRUCTURE OF HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH GMP FROM LEGIONELLA PNEUMOPHILA
Descriptor:Purine/pyrimidine phosphoribosyltransferase, GUANOSINE-5'-MONOPHOSPHATE
Authors:Zhang, N., Gong, X., Lu, M., Chen, X., Qin, X., Ge, H.
Deposit date:2015-11-17
Release date:2016-03-30
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
5DIK
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CRYSTAL STRUCTURE OF APO-LPG0406, A CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN FROM LEGIONELLA PNEUMOPHILA
Descriptor:Alkyl hydroperoxide reductase AhpD
Authors:Chen, X., Gong, X., Zhang, N., Ge, H.
Deposit date:2015-09-01
Release date:2015-10-14
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila
Protein Sci., 24, 2015
5DIP
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CRYSTAL STRUCTURE OF LPG0406 IN REDUCED FORM FROM LEGIONELLA PNEUMOPHILA
Descriptor:Alkyl hydroperoxide reductase AhpD, SODIUM ION, GLYCEROL
Authors:Chen, X., Gong, X., Zhang, N., Ge, H.
Deposit date:2015-09-01
Release date:2015-10-14
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila
Protein Sci., 24, 2015
5H6X
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THE CRYSTAL STRUCTURE OF RPOS FRAGMENT INCLUDING A PARTIAL REGION 1.2 AND REGION 2 FROM INTRACELLULAR PATHOGEN LEGIONELLA PNEUMOPHILA
Descriptor:RNA polymerase sigma factor RpoS, SODIUM ION, GLYCEROL
Authors:Zhang, N., Chen, X., Gong, X., Ge, H.
Deposit date:2016-11-15
Release date:2017-11-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila
Crystals, 8, 2018
5XJY
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CRYO-EM STRUCTURE OF HUMAN ABCA1
Descriptor:ATP-binding cassette sub-family A member 1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Qian, H.W., Yan, N., Gong, X.
Deposit date:2017-05-04
Release date:2017-06-07
Last modified:2017-07-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the Human Lipid Exporter ABCA1.
Cell, 169, 2017
2KJF
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THE SOLUTION STRUCTURE OF THE CIRCULAR BACTERIOCIN CARNOCYCLIN A (CCLA)
Descriptor:Carnocyclin-A
Authors:Martin-Visscher, L.A., Gong, X., Duszyk, M., Vederas, J.
Deposit date:2009-05-28
Release date:2009-08-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The three-dimensional structure of carnocyclin A reveals that many circular bacteriocins share a common structural motif.
J.Biol.Chem., 284, 2009
2LQV
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YEBF
Descriptor:Protein yebF
Authors:Prehna, G., Zhang, G., Gong, X., Duszyk, M., Okon, M., Mcintosh, L.P., Weiner, J.H., Strynadka, N.C.J.
Deposit date:2012-03-16
Release date:2012-06-13
Last modified:2012-07-25
Method:SOLUTION NMR
Cite:A Protein Export Pathway Involving Escherichia coli Porins.
Structure, 20, 2012
4IU8
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CRYSTAL STRUCTURE OF A MEMBRANE TRANSPORTER (SELENOMETHIONINE DERIVATIVE)
Descriptor:Nitrite extrusion protein 2, NITRATE ION
Authors:Yan, H., Huang, W., Yan, C., Gong, X., Jiang, S., Zhao, Y., Wang, J., Shi, Y.
Deposit date:2013-01-20
Release date:2013-04-17
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
4IU9
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CRYSTAL STRUCTURE OF A MEMBRANE TRANSPORTER
Descriptor:Nitrite extrusion protein 2
Authors:Yan, H., Huang, W., Yan, C., Gong, X., Jiang, S., Zhao, Y., Wang, J., Shi, Y.
Deposit date:2013-01-20
Release date:2013-04-17
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
4O6Y
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CRYSTAL STRUCTURE OF CYTOCHROME B561
Descriptor:Probable transmembrane ascorbate ferrireductase 2, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Lu, P., Ma, D., Yan, C., Gong, X., Du, M., Shi, Y.
Deposit date:2013-12-24
Release date:2014-02-05
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
4O79
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CRYSTAL STRUCTURE OF ASCORBATE-BOUND CYTOCHROME B561, CRYSTAL SOAKED IN 1 M L-ASCORBATE FOR 10 MINUTES
Descriptor:Probable transmembrane ascorbate ferrireductase 2, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Lu, P., Ma, D., Yan, C., Gong, X., Du, M., Shi, Y.
Deposit date:2013-12-24
Release date:2014-02-05
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
4O7G
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CRYSTAL STRUCTURE OF ASCORBATE-BOUND CYTOCHROME B561, CRYSTAL SOAKED IN 1 M L-ASCORBATE FOR 40 MINUTES
Descriptor:Probable transmembrane ascorbate ferrireductase 2, PROTOPORPHYRIN IX CONTAINING FE, ASCORBIC ACID, ...
Authors:Lu, P., Ma, D., Yan, C., Gong, X., Du, M., Shi, Y.
Deposit date:2013-12-24
Release date:2014-02-05
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
5GYY
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PLANT RECEPTOR COMPLEX
Descriptor:S-receptor kinase SRK9, S-locus protein 11, N-ACETYL-D-GLUCOSAMINE
Authors:Ma, R., Han, Z., Hu, Z., Lin, G., Gong, X., Zhang, H., June, N., Chai, J.
Deposit date:2016-09-24
Release date:2017-09-27
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Plant receptor complex at 2.35 Angstroms resolution
To Be Published
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