1SOR | | AQUAPORIN-0 MEMBRANE JUNCTIONS REVEAL THE STRUCTURE OF A CLOSED WATER PORE | | Descriptor: | Aquaporin-0 | | Authors: | Gonen, T., Sliz, P., Kistler, J., Cheng, Y., Walz, T. | | Deposit date: | 2004-03-15 | | Release date: | 2004-05-11 | | Last modified: | 2018-01-31 | | Method: | ELECTRON CRYSTALLOGRAPHY (3 Å) | | Cite: | Aquaporin-0 membrane junctions reveal the structure of a closed water pore
Nature, 429, 2004
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2B6O | | ELECTRON CRYSTALLOGRAPHIC STRUCTURE OF LENS AQUAPORIN-0 (AQP0) (LENS MIP) AT 1.9A RESOLUTION, IN A CLOSED PORE STATE | | Descriptor: | Lens fiber major intrinsic protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE | | Authors: | Gonen, T., Cheng, Y., Sliz, P., Hiroaki, Y., Fujiyoshi, Y., Harrison, S.C., Walz, T. | | Deposit date: | 2005-10-03 | | Release date: | 2005-12-06 | | Last modified: | 2018-07-18 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.9 Å) | | Cite: | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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2B6P | | X-RAY STRUCTURE OF LENS AQUAPORIN-0 (AQP0) (LENS MIP) IN AN OPEN PORE STATE | | Descriptor: | Lens fiber major intrinsic protein | | Authors: | Gonen, T., Cheng, Y., Sliz, P., Hiroaki, Y., Fujiyoshi, Y., Harrison, S.C., Walz, T. | | Deposit date: | 2005-10-03 | | Release date: | 2005-12-06 | | Last modified: | 2011-10-26 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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6C9I | | SINGLE-PARTICLE RECONSTRUCTION OF DARP14 - A DESIGNED PROTEIN SCAFFOLD DISPLAYING ~17KDA DARPIN PROTEINS - SCAFFOLD | | Descriptor: | DARP14 - Subunit A with DARPin, DARP14 - Subunit B | | Authors: | Gonen, S., Liu, Y., Yeates, T.O., Gonen, T. | | Deposit date: | 2018-01-26 | | Release date: | 2018-03-21 | | Last modified: | 2018-04-11 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C9K | | SINGLE-PARTICLE RECONSTRUCTION OF DARP14 - A DESIGNED PROTEIN SCAFFOLD DISPLAYING ~17KDA DARPIN PROTEINS | | Descriptor: | DARP14 - Subunit A with DARPin, DARP14 - Subunit B | | Authors: | Gonen, S., Liu, Y., Yeates, T.O., Gonen, T. | | Deposit date: | 2018-01-26 | | Release date: | 2018-03-21 | | Last modified: | 2018-04-11 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6MXF | | MICROED STRUCTURE OF THIOSTREPTON AT 1.9 A RESOLUTION | | Descriptor: | Thiostrepton | | Authors: | Jones, C.G., Martynowycz, M.W., Hattne, J., Fulton, T., Stoltz, B.M., Rodriguez, J.A., Nelson, H.M., Gonen, T. | | Deposit date: | 2018-10-30 | | Release date: | 2018-11-21 | | Last modified: | 2019-01-02 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.91 Å) | | Cite: | The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination.
ACS Cent Sci, 4, 2018
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3J07 | | MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | | Descriptor: | Alpha-crystallin B chain | | Authors: | Jehle, S., Vollmar, B., Bardiaux, B., Dove, K.K., Rajagopal, P., Gonen, T., Oschkinat, H., Klevit, R.E. | | Deposit date: | 2011-04-27 | | Release date: | 2016-01-20 | | Last modified: | 2016-11-23 | | Method: | SOLID-STATE NMR (20 Å), SOLUTION SCATTERING, ELECTRON MICROSCOPY | | Cite: | N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3J41 | | PSEUDO-ATOMIC MODEL OF THE AQUAPORIN-0/CALMODULIN COMPLEX DERIVED FROM ELECTRON MICROSCOPY | | Descriptor: | Lens fiber major intrinsic protein, Calmodulin, CALCIUM ION | | Authors: | Reichow, S.L., Clemens, D.M., Freites, J.A., Nemeth-Cahalan, K.L., Heyden, M., Tobias, D.J., Hall, J.E., Gonen, T. | | Deposit date: | 2013-05-31 | | Release date: | 2013-07-31 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (25 Å) | | Cite: | Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.
Nat.Struct.Mol.Biol., 20, 2013
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3J4G | |
3J4Q | |
3J4R | |
3J6K | |
3J7B | | CATALASE SOLVED AT 3.2 ANGSTROM RESOLUTION BY MICROED | | Descriptor: | Catalase, PROTOPORPHYRIN IX CONTAINING FE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Nannenga, B.L., Shi, D., Hattne, J., Reyes, F.E., Gonen, T. | | Deposit date: | 2014-06-09 | | Release date: | 2014-10-08 | | Last modified: | 2015-04-08 | | Method: | ELECTRON CRYSTALLOGRAPHY (3.2 Å) | | Cite: | Catalase solved at 3.2 Angstrom resolution by MicroED
eLife, 2014
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4JR9 | | CRYSTAL STRUCTURE OF NITRATE/NITRITE EXCHANGER NARK | | Descriptor: | Nitrite extrusion protein 1, Immunoglobulin Gamma-2a, Heavy chain, ... | | Authors: | Zheng, H., Wisedchaisri, G., Gonen, T. | | Deposit date: | 2013-03-21 | | Release date: | 2013-05-15 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of a nitrate/nitrite exchanger.
Nature, 497, 2013
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4JRE | | CRYSTAL STRUCTURE OF NITRATE/NITRITE EXCHANGER NARK WITH NITRITE BOUND | | Descriptor: | Nitrite extrusion protein 1, Immunoglobulin Gamma-2a, Heavy chain, ... | | Authors: | Zheng, H., Wisedchaisri, G., Gonen, T. | | Deposit date: | 2013-03-21 | | Release date: | 2013-05-15 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of a nitrate/nitrite exchanger.
Nature, 497, 2013
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4QIQ | | CRYSTAL STRUCTURE OF D-XYLOSE-PROTON SYMPORTER | | Descriptor: | D-xylose-proton symporter, ZINC ION | | Authors: | Wisedchaisri, G., Park, M., Iadanza, M.G., Zheng, H., Gonen, T. | | Deposit date: | 2014-06-01 | | Release date: | 2014-08-06 | | Last modified: | 2014-08-27 | | Method: | X-RAY DIFFRACTION (3.51 Å) | | Cite: | Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.
Nat Commun, 5, 2014
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4RIL | | STRUCTURE OF THE AMYLOID FORMING SEGMENT, GAVVTGVTAVA, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 68-78, DETERMINED BY ELECTRON DIFFRACTION | | Descriptor: | Alpha-synuclein | | Authors: | Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S. | | Deposit date: | 2014-10-06 | | Release date: | 2015-08-26 | | Last modified: | 2018-04-25 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.43 Å) | | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
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4TQL | | COMPUTATIONALLY DESIGNED THREE HELIX BUNDLE | | Descriptor: | Three helix bundle | | Authors: | Nannenga, B.L., Oberdorfer, G., DiMaio, F., Baker, D., Gonen, T. | | Deposit date: | 2014-06-11 | | Release date: | 2014-10-15 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | High thermodynamic stability of parametrically designed helical bundles.
Science, 346, 2014
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4UOS | | THERMODYNAMIC HYPERSTABILITY IN PARAMETRICALLY DESIGNED HELICAL BUNDLES | | Descriptor: | DESIGNED HELICAL BUNDLE | | Authors: | Oberdorfer, G., Huang, P., Pei, X.Y., Xu, C., Gonen, T., Nannenga, B., DiMaio, D., Rogers, J., Luisi, B.F., Baker, D. | | Deposit date: | 2014-06-09 | | Release date: | 2014-11-05 | | Last modified: | 2016-12-14 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
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4UOT | | THERMODYNAMIC HYPERSTABILITY IN PARAMETRICALLY DESIGNED HELICAL BUNDLES | | Descriptor: | DESIGNED HELICAL BUNDLE 5H2L | | Authors: | Oberdorfer, G., Huang, P., Pei, X.Y., Xu, C., Gonen, T., Nannenga, B., DiMaio, D., Rogers, J., Luisi, B.F., Baker, D. | | Deposit date: | 2014-06-09 | | Release date: | 2014-11-05 | | Last modified: | 2014-11-19 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
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4ZNN | | MICROED STRUCTURE OF THE SEGMENT, GVVHGVTTVA, FROM THE A53T FAMILIAL MUTANT OF PARKINSON'S DISEASE PROTEIN, ALPHA-SYNUCLEIN RESIDUES 47-56 | | Descriptor: | Alpha-synuclein | | Authors: | Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S. | | Deposit date: | 2015-05-05 | | Release date: | 2015-09-09 | | Last modified: | 2017-09-06 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.41 Å) | | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
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5A3E | |
5I9S | | MICROED STRUCTURE OF PROTEINASE K AT 1.75 A RESOLUTION | | Descriptor: | Proteinase K, SULFATE ION | | Authors: | Hattne, J., Shi, D., de la Cruz, M.J., Reyes, F.E., Gonen, T. | | Deposit date: | 2016-02-20 | | Release date: | 2016-06-08 | | Last modified: | 2018-08-22 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.75 Å) | | Cite: | Modeling truncated pixel values of faint reflections in MicroED images.
J.Appl.Crystallogr., 49, 2016
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5K7N | | MICROED STRUCTURE OF TAU VQIVYK PEPTIDE AT 1.1 A RESOLUTION | | Descriptor: | VQIVYK | | Authors: | de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T. | | Deposit date: | 2016-05-26 | | Release date: | 2017-04-05 | | Last modified: | 2018-08-22 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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5K7O | | MICROED STRUCTURE OF LYSOZYME AT 1.8 A RESOLUTION | | Descriptor: | Lysozyme C, CHLORIDE ION, SODIUM ION | | Authors: | de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T. | | Deposit date: | 2016-05-26 | | Release date: | 2017-04-05 | | Last modified: | 2018-08-22 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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